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Imbalance of Regulatory and Cytotoxic SARS-CoV-2-Reactive CD4+ T Cells in COVID-19

Cell(2020)10.1016/j.cell.2020.10.001Source: DataRank Database

Imbalance of Regulatory and Cytotoxic SARS-CoV-2-Reactive CD4+ T Cells in COVID-19 is a research paper published in Cell (2020). On theSindex it has a DataRank of 0.960. It has been cited 599 times.

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0.960DataRank · unranked

Scored on demand from live citation data

Open Access599 citations

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Linked data & code

geo gen

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (18 grants)Impact (FWCI 11.25)OA: bronzeTopics (94)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 100%Citation Network 0%

Base Score Contribution

0.960

From this paper's citation signal

Citation Network Contribution

Citation network not refreshed for this result

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Authors (15)

Ciro Ramírez-Suástegui ORCID,Vicente Fajardo ORCID,Serena Chee ORCID,Anthony Kusnadi ORCID,Hayley Simon ORCID

Live enrichment

PubMed:33096020 PMC:PMC7534589 OpenAlex:https://openalex.org/W3090209951

National Institutes of Health

Grant: U19AI118626

National Institutes of Health

Grant: R01HL114093

National Institutes of Health

Grant: U19AI142742-0S1

National Institutes of Health

Grant: S10OD025052

National Institutes of Health

Grant: S10RR027366

National Institutes of Health

Grant: U19AI14274

National Institutes of Health

Grant: R35-GM128938

National Institutes of Health

Grant: BD FACSAria-II

NIGMS NIH HHS

Grant: R35 GM128938

Cancer Research UK

Grant: 21998

NIAID NIH HHS

Grant: U19 AI142742

National Institutes of Health

Grant: 1S10RR027366-01A1

FACSAria II Cell Sorter

National Institutes of Health

Grant: 4U19AI118626-06

Human immune signatures of Dengue virus and Mycobacterium Tuberculosis exposure in infection, disease and vaccination

National Institutes of Health

Grant: 1R01HL114093-01

Epigenomics of T cells and innate immune cells in human asthma

National Institutes of Health

Grant: 5U19AI142742-03

Functional and dysfunctional human CD4 T cell and B cell responses to bacteria and viruses

National Institutes of Health

Grant: 3R35GM128938-07S1

Studying the function of human genetic variation in the light of 3D genome organization

National Institutes of Health

Grant: 1S10OD025052-01

NovaSeq5000 High Throughput Sequencer

National Institute for Health Research (NIHR)

FWCI

11.25

Citation Percentile

1.0%

Citation Trend

2020

2021

2022

2023

2024

2025

2026

bronzeLicense: Elsevier Non-Commercial

journalhttp://www.cell.com/article/S0092867420313076/pdf

publisherhttp://www.cell.com/article/S0092867420313076/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0092867420313076?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0092867420313076?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.cell.2020.10.001

Fields of Study

SARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research StudiesImmune responses and vaccinations0301 basic medicine03 medical and health sciences0302 clinical medicineAdultAgedAged, 80 and overAntibodies, ViralCD4 Lymphocyte CountCOVID-19Cohort StudiesEnglandFemaleHumansMaleMiddle AgedReverse Transcriptase Polymerase Chain ReactionSARS-CoV-2Severity of Illness IndexSingle-Cell AnalysisSpike Glycoprotein, CoronavirusT Follicular Helper CellsT-Lymphocytes, CytotoxicT-Lymphocytes, RegulatoryTranscriptome

MeSH Terms

T Follicular Helper CellsCOVID-19SARS-CoV-2AdultAgedAged, 80 and overAntibodies, ViralEnglandFemaleHumansMaleMiddle AgedSeverity of Illness IndexT-Lymphocytes, CytotoxicCohort StudiesCD4 Lymphocyte CountReverse Transcriptase Polymerase Chain ReactionT-Lymphocytes, RegulatorySingle-Cell AnalysisTranscriptomeSpike Glycoprotein, Coronavirus

Keywords

BiologyCoronavirus disease 2019 (COVID-19)Cytotoxic T cellSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)2019-20 coronavirus outbreakVirologyGeneticsInfectious disease (medical specialty)OutbreakIn vitroInternal medicineDiseaseHumanCytotoxicArteT(reg)Cd4(+) T CellsT(fh)Scrna-seqSingle-cell Rna SequencingCovid-19Sars-cov-2Antigen-Reactive T Cell EnrichmentCd4-CtlsAdultMale570T Follicular Helper Cells610Antibodies, ViralSeverity of Illness IndexT-Lymphocytes, RegulatoryGeneral Biochemistry, Genetics and Molecular BiologyArticleCohort StudiesHumansAgedAged, 80 and overReverse Transcriptase Polymerase Chain ReactionMiddle AgedCD4 Lymphocyte CountEnglandSpike Glycoprotein, CoronavirusFemaleSingle-Cell AnalysisT-Lymphocytes, Cytotoxic

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being