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Modular design of synthetic receptors for programmed gene regulation in cell therapies

Cell(2022)10.1016/j.cell.2022.03.023Source: DataRank Database

Modular design of synthetic receptors for programmed gene regulation in cell therapies is a research paper published in Cell (2022). On theSindex it has a DataRank of 0. It has been cited 196 times.

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Open Access196 citations

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Enrichment:Funding (24 grants)OA: greenTopics (30)IDs (PubMed, PMC)Annotations (2)

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Authors (10)

Raymond Liu ORCID,Julie Garcia ORCID,Axel Hyrenius‐Wittsten ORCID,Dan I. Piraner ORCID,Josef Alavi ORCID

Live enrichment

PubMed:35427499 PMC:PMC9108009

National Cancer Institute

Grant: DP2 CA239143

National Cancer Institute

Grant: 5F30CA250247-02

Next-generation Ligand-dependent Transcriptional Switch Receptors for the Control and Customization of Cell Therapeutics

National Cancer Institute

Grant: 5T32AI07334-29

Defense Advanced Research Projects Agency

Grant: D16AP00142

Defense Advanced Research Projects Agency

Grant: 1DP2AI131083

NIBIB

Grant: R01EB029483

NIAID NIH HHS

Grant: DP2 AI131083

NIH HHS

Grant: S10 OD021822

NCI NIH HHS

Grant: R01 CA118919

NCI NIH HHS

Grant: R01 CA129491

NIDDK NIH HHS

Grant: P30 DK063720

NIAID NIH HHS

Grant: T32 AI007334

NIGMS NIH HHS

Grant: T32 GM136547

NCI NIH HHS

Grant: F30 CA250247

National Institutes of Health

Grant: 5P30DK063720-03

ISLET PRODUCTION FACILITY CORE

National Institutes of Health

Grant: 5R01EB029483-03

Synthetic toolkit for precision gene expression control and signal processing in mammalian cells

National Institutes of Health

Grant: 1DP2AI131083-01

Combatting antibiotic resistance with synthetic biology technologies

National Institutes of Health

Grant: 1S10OD021822-01

BD FACSAria Fusion Cell Sorter

National Institutes of Health

Grant: 5T32AI007334-02

MOLECULAR AND CELLULAR IMMUNOLOGY

National Institutes of Health

Grant: 1DP2CA239143-01

Engineering the Next-generation of Custom Immune Cell Therapies

National Institutes of Health

Gilead Sciences

Parker Institute for Cancer Immunotherapy

Merck Sharp and Dohme

greenLicense: Elsevier Non-Commercial

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/9108009

publisherhttps://api.elsevier.com/content/article/PII:S0092867422003336?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0092867422003336?httpAccept=text/plain

https://doi.org/10.1016/j.cell.2022.03.023

https://pubmed.ncbi.nlm.nih.gov/35427499

MeSH Terms

T-LymphocytesHumansReceptors, Antigen, T-CellSynthetic BiologyReceptors, ArtificialCell- and Tissue-Based Therapy

Keywords

Cell therapyCancer ImmunotherapySynthetic BiologyCar-t CellsSynnotch5.2 Cellular and gene therapies1.1 Normal biological development and functioningT-LymphocytesCell- and Tissue-Based TherapyReceptors, Antigen, T-CellBioengineeringReceptors, ArtificialBiological SciencesStem Cell ResearchT-CellMedical and Health SciencesUnderpinning researchAntigenReceptorsArtificialHumansGeneric health relevanceDevelopment of treatments and therapeutic interventionsDevelopmental Biology