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MDA5 Governs the Innate Immune Response to SARS-CoV-2 in Lung Epithelial Cells

Pilot corpus: NIH-funded biomedical datasets. Any DOI can be scored on demand — network effects sharpen as coverage grows.

MDA5 Governs the Innate Immune Response to SARS-CoV-2 in Lung Epithelial Cells

Cell Reports(2021)10.1016/j.celrep.2020.108628Source: DataRank Database

MDA5 Governs the Innate Immune Response to SARS-CoV-2 in Lung Epithelial Cells is a research paper published in Cell Reports (2021). On theSindex it has a DataRank of 0. It has been cited 414 times.

N/A

0DataRank · unranked

Scored on demand from live citation data

Open Access414 citations

Cite:

Linked data & code

hpa

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (18 grants)Impact (FWCI 26.46)OA: goldTopics (45)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

FFindable (1/2)

Has DOI

AAccessible (1/2)

Open Access

IInteroperable (0/2)

RReusable (0/3)

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Authors (16)

Laura Riva ORCID,Yuan Pu ORCID,Laura Martin‐Sancho ORCID,Jun Kanamune,Yuki Yamamoto ORCID

Live enrichment

PubMed:33440148 PMC:PMC7832566 OpenAlex:https://openalex.org/W3092016255

National Institutes of Health

Grant: NR-52281

National Institute of Allergy and Infectious Diseases

Grant: HHSN272201400008C

National Institute of Allergy and Infectious Diseases

Grant: U19AI142733

National Institute of Allergy and Infectious Diseases

Grant: U19AI135972

National Institute of Allergy and Infectious Diseases

Grant: R01 AI127302-01A1

National Institute of Allergy and Infectious Diseases

Grant: U19 AI118610

National Cancer Institute

Grant: U54CA260560

JPB Foundation

Grant: 2020-218415

JPB Foundation

Grant: 2020-215611

National Center for Advancing Translational Sciences

Grant: UL1 TR002389

Defense Advanced Research Projects Agency

Grant: HR0011-19-2-0020

NIAID NIH HHS

Grant: R01 AI127302

NCATS NIH HHS

Grant: UL1 TR001422

NCI NIH HHS

Grant: P30 CA060553

NCI NIH HHS

Grant: P30 CA030199

Centers for Disease Control and Prevention

U.S. Department of Defense

Pfizer

FWCI

26.46

Citation Percentile

1.0%

Citation Trend

2020

2021

2022

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://doi.org/10.1016/j.celrep.2020.108628

publisherhttps://doi.org/10.1016/j.celrep.2020.108628

publisherhttps://api.elsevier.com/content/article/PII:S221112472031617X?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S221112472031617X?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/33440148

Fields of Study

interferon and immune responsesSARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research Studies

MeSH Terms

Interferon-Induced Helicase, IFIH1COVID-19SARS-CoV-2Cell LineEpithelial CellsHumansImmunity, InnateInterferonsRNA, Double-StrandedVirus ReplicationSignal TransductionRNA HelicasesRNA InterferenceRNA, Small InterferingInterferon Regulatory FactorsInterferon Regulatory Factor-3Transcription Factor RelAInduced Pluripotent Stem Cells

Keywords

MDA5Innate immune systemIRF3InterferonBiologyImmune systemImmunologyVirologyCoronavirusViral replicationRIG-IVirusRNADiseaseMedicineGeneCoronavirus disease 2019 (COVID-19)Infectious disease (medical specialty)RNA interferenceGeneticsLung Epithelial CellsIrf5Nf-κb/p65Sars-cov-2

Sustainable Development Goals

SDG 0: Good health and well-being

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