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Whole-genome characterization of lung adenocarcinomas lacking alterations in the RTK/RAS/RAF pathway

Cell Reports(2021)10.1016/j.celrep.2021.108707Source: DataRank Database

Whole-genome characterization of lung adenocarcinomas lacking alterations in the RTK/RAS/RAF pathway is a research paper published in Cell Reports (2021). On theSindex it has a DataRank of 1.1. It has been cited 32 times, with 23 citing works in its 1-hop citation network.

N/A

1.1DataRank · unranked

Scored on demand from live citation data

Open Access32 citations · 23 citing works in its network

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Linked data & code

dbgap

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (24 grants)Impact (FWCI 1.73)OA: goldTopics (46)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 46%Citation Network 54%

Base Score Contribution

0.524

From this paper's citation signal

Citation Network Contribution

0.618

From 19 citing papers with measurable signal

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Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 23 citers.

A cancer graph: a lung cancer property graph database in Neo4j
BMC Research Notes202213 citations17 referencesContributes 0.155
Genomic Profiling of Lung Adenocarcinoma in Never-Smokers
Journal of Clinical Oncology2021112 citations40 referencesContributes 0.118
Genomic and evolutionary classification of lung cancer in never smokers
Nature Genetics2021248 citations113 referencesContributes 0.049
PROTAC therapy as a new targeted therapy for lung cancer
Molecular Therapy202283 citations92 referencesContributes 0.048
Combinatorial Inactivation of Tumor Suppressors Efficiently Initiates Lung Adenocarcinoma with Therapeutic Vulnerabilities
Cancer Research202218 citations78 referencesContributes 0.038

Authors (82)

Xiaotong Yao ORCID,Siddhartha Devarakonda ORCID,Aditya Deshpande ORCID,Jeffrey S. Damrauer ORCID,Tiago C. Silva ORCID

Live enrichment

PubMed:33535033 PMC:PMC8009291 OpenAlex:https://openalex.org/W3127767100

NCI NIH HHS

Grant: U24 CA210949

NCI NIH HHS

Grant: U24 CA126546

NCI NIH HHS

Grant: U24 CA143867

NCI NIH HHS

Grant: U24 CA210988

NCI NIH HHS

Grant: U24 CA210999

NCI NIH HHS

Grant: R01 CA218668

NCI NIH HHS

Grant: U24 CA210950

NCI NIH HHS

Grant: U24 CA210989

NCI NIH HHS

Grant: U24 CA211006

NCI NIH HHS

Grant: U24 CA210952

NCI NIH HHS

Grant: U24 CA210969

NCI NIH HHS

Grant: U24 CA211000

NCI NIH HHS

Grant: P30 CA008748

NCI NIH HHS

Grant: R35 CA197568

NIEHS NIH HHS

Grant: P30 ES010126

NCI NIH HHS

Grant: U24 CA210990

NCI NIH HHS

Grant: U24 CA210957

NCI NIH HHS

Grant: U24 CA210974

NCI NIH HHS

Grant: U24 CA210978

National Institutes of Health

Grant: 5U24CA211006-05

Deep Discovery and Clinical Interpretation of Germline and Somatic Cancer Drivers

National Institutes of Health

Grant: 5U24CA210999-03

Global Infrastructure for Collaborative High-throughput Cancer Genomics Analysis

National Institutes of Health

Grant: 5U24CA210974-05

Visualization hub for genomics data exploration and translational discovery

Canadian Institutes of Health Research

Grant: unidentified

unidentified

National Institutes of Health

FWCI

1.73

Citation Percentile

0.8%

Citation Trend

2021

2022

2023

2024

2025

2026

goldLicense: CC BY NC ND

journalhttp://www.cell.com/article/S2211124721000206/pdf

publisherhttp://www.cell.com/article/S2211124721000206/pdf

publisherhttps://api.elsevier.com/content/article/PII:S2211124721000206?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2211124721000206?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.celrep.2021.108707

Fields of Study

Cancer Genomics and DiagnosticsLung Cancer Treatments and MutationsCholangiocarcinoma and Gallbladder Cancer Studies03 medical and health sciences0302 clinical medicineAdenocarcinoma of LungHumansKelch-Like ECH-Associated Protein 1Lung NeoplasmsTachykininsWhole Genome Sequencing

MeSH Terms

Kelch-Like ECH-Associated Protein 1Whole Genome SequencingAdenocarcinoma of LungHumansLung NeoplasmsTachykinins

Keywords

STK11BiologyGenomeCancer researchGenome instabilitySuppressorAdenocarcinomaGeneticsTranscription (linguistics)Whole genome sequencingMutantGeneKRASMutationCancerDNADNA damageGenome analysisOncogeneTumor suppressorLung adenocarcinomaStructural VariationDriverTcgaNoncodingPrecision OncologyQH301-705.5Biology (General)Article

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being