Pilot corpus: NIH-funded biomedical datasets. Any DOI can be scored on demand — network effects sharpen as coverage grows.

Loop extrusion promotes an alternate pathway for isotype switching

Cell Reports(2021)10.1016/j.celrep.2021.110059Source: DataRank Database

Loop extrusion promotes an alternate pathway for isotype switching is a research paper published in Cell Reports (2021). On theSindex it has a DataRank of 0. It has been cited 17 times.

N/A

0DataRank · unranked

Scored on demand from live citation data

Open Access17 citations

Download PDF

Cite:

Linked data & code

geo

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (7 grants)Impact (FWCI 0.82)OA: goldTopics (61)IDs (PubMed, PMC, OpenAlex)Annotations (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

FAIR checklist signals are shown for context only and do not affect DataRank scoring.

Run a calibrated FAIR evaluation for this paper →

We only score data papers we can read in full — never from an abstract alone.

Authors (8)

Robert Wuerffel,José Fernando Cantillo ORCID,Saurabh Priyadarshi,Xue Lei ORCID,Jie Liang ORCID

Live enrichment

PubMed:34818547 PMC:PMC8979556 OpenAlex:https://openalex.org/W3215067921

National Institutes of Health

Grant: RO1AI121286

National Institutes of Health

Grant: R21AI133050

NIAID NIH HHS

Grant: R21 AI126308

NIAID NIH HHS

Grant: R01 AI121286

NIGMS NIH HHS

Grant: R35 GM127084

NIAID NIH HHS

Grant: R21 AI151892

National Institutes of Health

Grant: 5R01AI121286-05

Chromatin infrastructure of the Igh locus and its influence on VH gene usage

FWCI

0.82

Citation Percentile

0.7%

Citation Trend

2022

2023

2024

2025

2026

goldLicense: CC BY NC ND

journalhttps://doi.org/10.1016/j.celrep.2021.110059

publisherhttps://doi.org/10.1016/j.celrep.2021.110059

publisherhttps://api.elsevier.com/content/article/PII:S221112472101545X?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S221112472101545X?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/34818547

Fields of Study

Genomics and Chromatin DynamicsRNA Research and SplicingDNA Repair Mechanisms0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

AnimalsB-LymphocytesChromatinCytidine DeaminaseImmunoglobulin EImmunoglobulin Heavy ChainsLymphocyte ActivationMaleMice, Inbred BALB CMice, Inbred C57BLPromoter Regions, GeneticRecombination, GeneticTranscription, GeneticImmunoglobulin Class SwitchingChromosome PairingMiceDNA Breaks

Keywords

IsotypeExtrusionImmunoglobulin class switchingLoop (graph theory)Cell biologyComputational biologyGeneticsBiologyChemistryAntibodyMathematicsMaterials scienceCombinatoricsIgEB cellsAid TargetingChromatin LoopingDna BreaksImmunoglobulin Class Switch RecombinationLoop ExtrusionSequential SwitchingBcr-negative B CellsMaleRecombination, GeneticB-LymphocytesMice, Inbred BALB CTranscription, GeneticImmunoglobulin ELymphocyte ActivationArticleChromatinMice, Inbred C57BLChromosome PairingMiceCytidine DeaminaseAnimalsImmunoglobulin Heavy ChainsPromoter Regions, Genetic

Loop extrusion promotes an alternate pathway for isotype switching

FAIR Checklist

Authors (8)

Funding (7 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)