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A Fc-enhanced NTD-binding non-neutralizing antibody delays virus spread and synergizes with a nAb to protect mice from lethal SARS-CoV-2 infection

Cell Reports(2022)10.1016/j.celrep.2022.110368Source: DataRank Database

A Fc-enhanced NTD-binding non-neutralizing antibody delays virus spread and synergizes with a nAb to protect mice from lethal SARS-CoV-2 infection is a research paper published in Cell Reports (2022). On theSindex it has a DataRank of 0. It has been cited 132 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access132 citations

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Linked data & code

cellosaurus emdb nct pdb

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (9 grants)OA: goldTopics (45)IDs (PubMed, PMC)Annotations (4)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (26)

Yaozong Chen ORCID,Irfan Ullah ORCID,Jérémie Prévost ORCID,William D. Tolbert ORCID,Kelly Symmes ORCID

Live enrichment

PubMed:35123652 PMC:PMC8786652

NIAID NIH HHS

Grant: R01 AI163395

Canadian Institutes of Health Research

Grant: unidentified

unidentified

National Institutes of Health

Grant: 5R01AI163395-03

Structure and Dynamics of the SARS-CoV-2 Spike Protein

Canada Excellence Research Chairs

Canadian Institutes of Health Research

Canada Foundation for Innovation

FRQS

Mitacs

NIH

goldLicense: CC BY NC ND

publisherhttp://www.cell.com/article/S2211124722000894/pdf

publisherhttps://api.elsevier.com/content/article/PII:S2211124722000894?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2211124722000894?httpAccept=text/plain

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8786652

https://doi.org/10.1016/j.celrep.2022.110368

Fields of Study

0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

AnimalsHumansMiceDisease Models, AnimalAntibodies, ViralEpitopesImmunization, PassiveAntibody-Dependent Cell CytotoxicityProtein ConformationProtein BindingImmunoglobulin Fab FragmentsImmunoglobulin Fc FragmentsAntibodies, NeutralizingSpike Glycoprotein, CoronavirusCOVID-19SARS-CoV-2COVID-19 Serotherapy

Keywords

CoronavirussynergyADCCspikeNon-neutralizing AntibodiesFc-effector FunctionsCovid-19Sars-cov-2K18-hace2 MiceProtein ConformationAntibody-Dependent Cell CytotoxicityImmunization, PassiveAntibodies, ViralAntibodies, NeutralizingArticleImmunoglobulin Fc FragmentsDisease Models, AnimalEpitopesImmunoglobulin Fab FragmentsMiceSpike Glycoprotein, CoronavirusAnimalsHumansCOVID-19 SerotherapyProtein Binding

Sustainable Development Goals

SDG 3: 3. Good health