William D. Tolbert

Also affiliated with Uniformed Services University of the Health Sciences

Immunology and MicrobiologyMedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

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Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 43 papers. Top paper: “Antigen-Induced Allosteric Changes in a Human IgG1 Fc Increase Low-Affinity Fcγ Receptor Binding”.

Antigen-Induced Allosteric Changes in a Human IgG1 Fc Increase Low-Affinity Fcγ Receptor Binding

Structure(2020)10.1016/j.str.2020.03.001

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44 citations

Daniel Deredge, Krishanu Ray, Neelakshi Gohain, William D. Tolbert, Anthony L. DeVico +4 more

The HIV-1 Env gp120 Inner Domain Shapes the Phe43 Cavity and the CD4 Binding Site

mBio(2020)10.1128/mbio.00280-20

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53 citations

William D. Tolbert, Halima Medjahed, Rebekah Sherburn, Navid Madani, Daria Zoubchenok +19 more

Stabilizing the HIV-1 Envelope Glycoprotein State 2A Conformation

Journal of Virology(2020)10.1128/jvi.01620-20

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12 citations

Shang Yu Gong, William D. Tolbert, Shilei Ding, Dung N. Nguyen, Jonathan Richard +6 more

Defining rules governing recognition and Fc-mediated effector functions to the HIV-1 co-receptor binding site

BMC Biology(2020)10.1186/s12915-020-00819-y

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28 citations

Rebekah Sherburn, Neelakshi Gohain, Shilei Ding, Robin Flinko, Chiara Orlandi +5 more

Recognition Patterns of the C1/C2 Epitopes Involved in Fc-Mediated Response in HIV-1 Natural Infection and the RV114 Vaccine Trial

mBio(2020)10.1128/mbio.00208-20

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6 citations

Verna Van, Rebekah Sherburn, Marina Tuyishime, Fang Yan, Dung N. Nguyen +10 more

Effects of gp120 Inner Domain (ID2) Immunogen Doses on Elicitation of Anti-HIV-1 Functional Fc-Effector Response to C1/C2 (Cluster A) Epitopes in Mice

Microorganisms(2020)10.3390/microorganisms8101490

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1 citations

William D. Tolbert, Suneetha Gottumukkala, Guillaume Beaudoin-Bussières, Andrés Finzi, Marzena Pazgier +1 more

Design of ultrahigh-affinity and dual-specificity peptide antagonists of MDM2 and MDMX for P53 activation and tumor suppression

Acta Pharmaceutica Sinica B(2021)10.1016/j.apsb.2021.06.010

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34 citations

Neelakshi Gohain, Si Chen, Yinghua Li, Xiaoyuan Zhao, Bo Li +6 more

Across Functional Boundaries: Making Nonneutralizing Antibodies To Neutralize HIV-1 and Mediate Fc-Mediated Effector Killing of Infected Cells

mBio(2021)10.1128/mbio.01405-21

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15 citations

Dung N. Nguyen, William D. Tolbert, Romain Gasser, Shilei Ding, Dani Vézina +8 more

Enhanced Ability of Plant-Derived PGT121 Glycovariants To Eliminate HIV-1-Infected Cells

Journal of Virology(2021)10.1128/jvi.00796-21

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16 citations

Shilei Ding, William D. Tolbert, Jérémie Prévost, Jonathan Richard, Hwi Min Gil +19 more

Near-Pan-neutralizing, Plasma Deconvoluted Antibody N49P6 Mimics Host Receptor CD4 in Its Quaternary Interactions with the HIV-1 Envelope Trimer

mBio(2021)10.1128/mbio.01274-21

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9 citations

Dung N. Nguyen, Zahra Rikhtegaran Tehrani, Mohammad M. Sajadi, Marzena Pazgier, William D. Tolbert

Structural Basis and Mode of Action for Two Broadly Neutralizing Antibodies Against SARS-CoV-2 Emerging Variants of Concern

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.08.02.454546

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22 citations

Yaozong Chen, Jérémie Prévost, Irfan Ullah, Maolin Lu, Shang Yu Gong +25 more

Engineered ACE2-Fc counters murine lethal SARS-CoV-2 infection through direct neutralization and Fc-effector activities

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.11.24.469776

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11 citations

Lulu Sun, Irfan Ullah, Guillaume Beaudoin-Bussières, Sai Priya Anand, Andrew P. Hederman +18 more

Nebulized delivery of a broadly neutralizing SARS-CoV-2 RBD-specific nanobody prevents clinical, virological and pathological disease in a Syrian hamster model of COVID-19

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.11.10.468147

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4 citations

Yaozong Chen, Negin P. Martin, Helle Bielefeldt‐Ohmann, Richard A. Bowen, William D. Tolbert +3 more

Across functional boundaries: making non-neutralizing antibodies to neutralize HIV-1 and mediate Fc-mediated effector killing of infected cells

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.08.13.456231

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2 citations

Dung N. Nguyen, William D. Tolbert, Romain Gasser, Shilei Ding, Dani Vézina +8 more

A Fc-enhanced NTD-binding non-neutralizing antibody delays virus spread and synergizes with a nAb to protect mice from lethal SARS-CoV-2 infection

Cell Reports(2022)10.1016/j.celrep.2022.110368

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132 citations

Yaozong Chen, Irfan Ullah, Jérémie Prévost, William D. Tolbert, Kelly Symmes +21 more

Decoding human-macaque interspecies differences in Fc-effector functions: The structural basis for CD16-dependent effector function in Rhesus macaques

Frontiers in Immunology(2022)10.3389/fimmu.2022.960411

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20 citations

Neelakshi Gohain, Paul G Kremer, Andrew P. Hederman, Dung N. Nguyen, Verna Van +8 more

Molecular basis for antiviral activity of two pediatric neutralizing antibodies targeting SARS-CoV-2 Spike RBD

iScience(2022)10.1016/j.isci.2022.105783

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10 citations

Jérémie Prévost, Irfan Ullah, Hugo Grisales Romero, Véronique Lisi, William D. Tolbert +36 more

Characterization of a Novel CD4 Mimetic Compound YIR-821 against HIV-1 Clinical Isolates

Journal of Virology(2022)10.1128/jvi.01638-22

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7 citations

Takeo Kuwata, William D. Tolbert, Jonathan Richard, Shilei Ding, Jérémie Prévost +12 more

Structure and Fc-Effector Function of Rhesusized Variants of Human Anti-HIV-1 IgG1s

Frontiers in Immunology(2022)10.3389/fimmu.2021.787603

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1 citations

Dung N. Nguyen, Marina Tuyishime, Andrew R. Crowley, Yaozong Chen, Shalini Jha +17 more

Plasma Human Immunodeficiency Virus 1 Soluble Glycoprotein 120 Association With Correlates of Immune Dysfunction and Inflammation in Antiretroviral Therapy–Treated Individuals With Undetectable Viremia

The Journal of Infectious Diseases(2023)10.1093/infdis/jiad503

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32 citations

Jonathan Richard, Catherine Bourassa, William D. Tolbert, Carl Chartrand‐Lefebvre, Gabrielle Gendron‐Lepage +23 more

Temsavir blocks the immunomodulatory activities of HIV-1 soluble gp120

Cell chemical biology(2023)10.1016/j.chembiol.2023.03.003

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30 citations

Jérémie Prévost, Catherine Bourassa, Nathalie Brassard, Marianne Boutin, Mehdi Benlarbi +14 more

Structure-function analyses reveal key molecular determinants of HIV-1 CRF01_AE resistance to the entry inhibitor temsavir

Nature Communications(2023)10.1038/s41467-023-42500-2

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13 citations

Yaozong Chen, Fei Zhou, William D. Tolbert, Romain Gasser, Halima Medjahed +11 more

Piperidine CD4-Mimetic Compounds Expose Vulnerable Env Epitopes Sensitizing HIV-1-Infected Cells to ADCC

Viruses(2023)10.3390/v15051185

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12 citations

William D. Tolbert, Huile Zhu, Daniel Lee, Lorie Marchitto, Tyler F. Higgins +12 more

The molecular basis of the neutralization breadth of the RBD-specific antibody CoV11

Frontiers in Immunology(2023)10.3389/fimmu.2023.1178355

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5 citations

Yaozong Chen, Lulu Sun, Mehdi Benlarbi, Shilei Ding, Rohini Manickam +10 more

Piperidine CD4-mimetic compounds expose vulnerable Env epitopes sensitizing HIV-1-infected cells to ADCC

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.23.533923

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5 citations

William D. Tolbert, Huile Zhu, Daniel Lee, Tyler F. Higgins, Xuchen Zhao +11 more

Structure-function Analyses Reveal Key Molecular Determinants of HIV-1 CRF01_AE Resistance to the Entry Inhibitor Temsavir

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.04.17.537181

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3 citations

Yaozong Chen, Fei Zhou, William D. Tolbert, Romain Gasser, Halima Medjahed +9 more

Plasmatic HIV-1 soluble gp120 is associated with immune dysfunction and inflammation in ART-treated individuals with undetectable viremia

medRxiv(2023)10.1101/2023.08.15.23294128

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1 citations

Jonathan Richard, Catherine Bourassa, William D. Tolbert, Carl Chartrand‐Lefebvre, Gabrielle Gendron‐Lepage +25 more

Three families of CD4-induced antibodies are associated with the capacity of plasma from people living with HIV to mediate ADCC in the presence of CD4-mimetics

Journal of Virology(2024)10.1128/jvi.00960-24

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11 citations

Lorie Marchitto, Étienne Bélanger, Mehdi Benlarbi, Guillaume Beaudoin-Bussières, Jérémie Prévost +13 more

The combination of three CD4-induced antibodies targeting highly conserved Env regions with a small CD4-mimetic achieves potent ADCC activity

Journal of Virology(2024)10.1128/jvi.01016-24

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9 citations

Jonathan Richard, Jérémie Prévost, Alexandra Tauzin, Derek Yang, Ta-Jung Chiu +18 more

Immune response profiles from humans experimentally exposed to Phlebotomus duboscqi bites

Frontiers in Immunology(2024)10.3389/fimmu.2024.1335307

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6 citations

Maha Abdeladhim, Clarissa Teixeira, Kelly A. Hummer, Matthew D. Wilkerson, Roseanne Ressner +13 more

Optimization of a Piperidine CD4-Mimetic Scaffold Sensitizing HIV-1 Infected Cells to Antibody-Dependent Cellular Cytotoxicity

ACS Medicinal Chemistry Letters(2024)10.1021/acsmedchemlett.4c00403

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2 citations

Ling Niu, Shilei Ding, Huile Zhu, William D. Tolbert, Halima Medjahed +6 more

Defining genetic diversity of rhesus macaque Fcγ receptors with long-read RNA sequencing

Frontiers in Immunology(2024)10.3389/fimmu.2023.1306292

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1 citations

Max M. He, David Easterhoff, Hèléne Fradin, Sarah L. Cocklin, Jacob Meyer +11 more

The combination of three CD4-induced antibodies targeting highly conserved Env regions with a small CD4-mimetic achieves potent ADCC activity

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.06.07.597978

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5 citations

Jonathan Richard, Jérémie Prévost, Alexandra Tauzin, Derek Yang, Ta-Jung Chiu +18 more

Three families of CD4-induced antibodies are associated with the capacity of plasma from people living with HIV to mediate ADCC in presence of CD4-mimetics

medRxiv(2024)10.1101/2024.06.02.24308281

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4 citations

Lorie Marchitto, Étienne Bélanger, Mehdi Benlarbi, Guillaume Beaudoin-Bussières, Jérémie Prévost +13 more

CD4 T cell counts are inversely correlated with anti-gp120 cluster A antibodies in antiretroviral therapy-treated PLWH

EBioMedicine(2025)10.1016/j.ebiom.2025.105856

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6 citations

Jonathan Richard, Tommaso Clemente, Catherine Bourassa, William D. Tolbert, Suneetha Gottumukkala +8 more

A comprehensive engineering strategy improves potency and manufacturability of a near pan-neutralizing antibody against HIV

Structure(2025)10.1016/j.str.2025.04.016

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5 citations

Abdolrahim Abbasi, Zahra Rikhtegaran Tehrani, Christine C. Siska, Rutilio H. Clark, Woo Chi +41 more

A gp41 HR2 residue modulates the susceptibility of HIV-1 envelope glycoproteins to small molecule inhibitors targeting gp120

Journal of Virology(2025)10.1128/jvi.02267-24

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4 citations

Ling Niu, Halima Medjahed, Shilei Ding, Mehdi Benlarbi, Étienne Bélanger +7 more

The asymmetric opening of HIV-1 Env by a potent CD4 mimetic enables anti-coreceptor binding site antibodies to mediate ADCC

Nature Communications(2025)10.1038/s41467-025-65866-x

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4 citations

Michael W. Grunst, Ling Niu, Marco A Díaz-Salinas, Li Zhu, William D. Tolbert +29 more

CD4-mimetics sensitize HIV-infected cells to ADCC mediated by plasma from persons with early-stage HIV-1 infection

Journal of Virology(2025)10.1128/jvi.00858-25

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3 citations

Alexandra Tauzin, Delia Pinto-Santini, Sayan Dasgupta, Derek Yang, William D. Tolbert +10 more

The impact of N-glycan conformational entropy on the binding affinity of Fc γ receptor IIIa/CD16a

Structure(2025)10.1016/j.str.2025.11.015

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1 citations

William D. Tolbert, Eliza Gazaway, Braulio G. Hernandez, Marek K. Korzeniowski, Zofia A. Dyba +7 more

CD4 T cell counts are inversely correlated with anti-cluster A antibodies in antiretroviral therapy-treated PLWH

medRxiv(2025)10.1101/2025.02.25.25322882

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0 citations

Jonathan Richard, Tommaso Clemente, Catherine Bourassa, William D. Tolbert, Suneetha Gottumukkala +8 more

Fostemsavir Decreases the Levels of Anti-gp120 CD4-Induced Antibodies in Heavily Treatment-Experienced People With HIV

The Journal of Infectious Diseases(2025)10.1093/infdis/jiaf461

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0 citations

Jonathan Richard, Tommaso Clemente, Catherine Bourassa, William D. Tolbert, Manyu Prakash +7 more

Optimization of VE607 to generate analogs with improved neutralization activities against SARS-CoV-2 variants

Journal of Virology(2025)10.1128/jvi.01034-25

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0 citations

Derek Yang, Irfan Ullah, Ling Niu, Matthew Unger, Marco A Díaz-Salinas +22 more