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Hyperactivating EZH2 to augment H3K27me3 levels in regulatory T cells enhances immune suppression by driving early effector differentiation

Cell Reports(2024)10.1016/j.celrep.2024.114724Source: DataRank Database

Hyperactivating EZH2 to augment H3K27me3 levels in regulatory T cells enhances immune suppression by driving early effector differentiation is a research paper published in Cell Reports (2024). On theSindex it has a DataRank of 0. It has been cited 25 times.

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0DataRank · unranked

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Open Access25 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (10 grants)OA: goldTopics (27)IDs (PubMed, PMC)Annotations (3)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (5)

Stephanie Silveria ORCID,Merve Özdemir ORCID,Srinivas Ramachandran ORCID,Michel DuPage ORCID,Janneke G. C. Peeters ORCID

Live enrichment

PubMed:39264807 PMC:PMC12052300

ZonMw

Grant: 45219210

American Cancer Society

Grant: RSG-22-026-01

NIH

Grant: 1DP2CA247830-01

Engineering precision cancer immunotherapy

NIH

Grant: R35GM133434

NCI NIH HHS

Grant: DP2 CA247830

PEW Charitable Trusts

University of Colorado School of Medicine, Anschutz Medical Campus

Dutch Research Council (NWO)

Saint Baldricks Foundation

Alexander and Margaret Stewart Trust

goldLicense: cc-by-nc-nd

GOLDhttps://doi.org/10.1016/j.celrep.2024.114724

publisherhttps://doi.org/10.1016/j.celrep.2024.114724

publisherhttps://api.elsevier.com/content/article/PII:S2211124724010751?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2211124724010751?httpAccept=text/plain

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12052300/pdf/nihms-2025380.pdf

Fields of Study

MedicineBiology

MeSH Terms

AnimalsMice, Inbred C57BLMiceHistonesCell DifferentiationAutoimmunityMethylationT-Lymphocytes, RegulatoryEnhancer of Zeste Homolog 2 ProteinCD28 Antigens

Keywords

AutoimmunityEpigeneticsEzh2Regulatory T cellsCp: ImmunologyHistonesMice, Inbred C57BLMiceCD28 AntigensAnimalsEnhancer of Zeste Homolog 2 ProteinCell DifferentiationT-Lymphocytes, RegulatoryMethylationArticle

Hyperactivating EZH2 to augment H3K27me3 levels in regulatory T cells enhances immune suppression by driving early effector differentiation

FAIR Checklist

Authors (5)

Funding (10 grants)

Open Access

Topics

Annotations (Europe PMC)