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Deciphering the cell type-specific and zonal distribution of drug-metabolizing enzymes, transporters, and transcription factors in livers of mice using single-cell transcriptomics

Drug Metabolism and Disposition(2024)10.1016/j.dmd.2024.100029Source: DataRank Database

Deciphering the cell type-specific and zonal distribution of drug-metabolizing enzymes, transporters, and transcription factors in livers of mice using single-cell transcriptomics is a research paper published in Drug Metabolism and Disposition (2024). On theSindex it has a DataRank of 0. It has been cited 3 times.

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Open Access3 citations

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Enrichment:Funding (5 grants)Impact (FWCI 0.53)OA: greenTopics (46)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (3)

Curtis D. Klaassen,Julia Yue Cui ORCID,Joe Jongpyo Lim ORCID

Live enrichment

PubMed:39919554 PMC:PMC13095463 OpenAlex:https://openalex.org/W4405338437

National Institutes of Health

Grant: F31DK139707

National Institute of Environmental Health Sciences

Grant: R01ES031098

National Institute of Environmental Health Sciences

Grant: R01ES030197

University of Washington

Grant: T32ES007032

University of Washington

Grant: P30ES007033

FWCI

0.53

Citation Percentile

0.7%

Citation Trend

2025

2026

greenLicense: http://www.elsevier.com/open-access/userlicense/1.0/

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC13095463/

publisherhttps://api.elsevier.com/content/article/PII:S0090955624158795?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0090955624158795?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.dmd.2024.100029

Fields of Study

Drug Transport and Resistance MechanismsPharmacogenetics and Drug MetabolismPancreatic function and diabetesAnimalsMiceLiverSingle-Cell AnalysisTranscriptomeHepatocytesTranscription FactorsGene Expression ProfilingMaleMembrane Transport ProteinsInactivation, MetabolicMice, Inbred C57BL

MeSH Terms

AnimalsLiverMaleInactivation, MetabolicMice, Inbred C57BLTranscription FactorsGene Expression ProfilingHepatocytesMembrane Transport ProteinsMiceSingle-Cell AnalysisTranscriptome

Keywords

TranscriptomeTransporterCellTranscription factorBiologyEnzymeDrugCell typeGene expressionCell biologyGeneComputational biologyPharmacologyBiochemistrysystems biologyDrug Metabolizing EnzymesSingle Cell Rna-sequencingSpatial DeconvolutionLiver Cell Types

Sustainable Development Goals

SDG 0: Good health and well-being

Deciphering the cell type-specific and zonal distribution of drug-metabolizing enzymes, transporters, and transcription factors in livers of mice using single-cell transcriptomics

FAIR Checklist

Authors (3)

Funding (5 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)