Fungal regulatory evolution: <i>cis</i> and <i>trans</i> in the balance is a research paper published in FEBS Letters (2009). On theSindex it has a DataRank of 1.1. It has been cited 25 times, with 17 citing works in its 1-hop citation network.
Regulatory divergence is likely a major driving force in evolution. Comparative genomics is being increasingly used to infer the evolution of gene regulation. Ascomycota fungi are uniquely suited among eukaryotes for regulatory evolution studies, due to broad phylogenetic scope, many sequenced genomes, and tractability of genomic analysis. Here we review recent advances in the identification of the contribution of cis- and trans-factors to expression divergence. Whereas current strategies have led to the discovery of surprising signatures and mechanisms, we still understand very little about the adaptive role of regulatory evolution. Empirical studies including experimental evolution, comparative functional genomics and hybrid and engineered strains are showing early promise toward deciphering the contribution of regulatory divergence to adaptation.
FAIR checklist signals are shown for context only and do not affect DataRank scoring.
Base Score Contribution
0.489
From this paper's citation signal
Citation Network Contribution
0.570
From 16 citing papers with measurable signal
Ranked by citation count — the same ordering the engine uses when summing log1p(Cq) over citers.
DataRank blends this paper's own citation count with the influence of the papers that cite it. Here, roughly 46% comes from its base citations and 54% from the citation network (16 citing papers contributed measurable signal).
Citers are pulled from OpenAlex sorted by cited_by_count:descand capped per paper, so when the cap binds we keep the highest-signal references and the score is reproducible across reruns.
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