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Direct microglia replacement reveals pathologic and therapeutic contributions of brain macrophages to a monogenic neurological disease

Immunity(2025)10.1016/j.immuni.2025.03.019Source: DataRank Database

Direct microglia replacement reveals pathologic and therapeutic contributions of brain macrophages to a monogenic neurological disease is a research paper published in Immunity (2025). On theSindex it has a DataRank of 0. It has been cited 23 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access23 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (18 grants)Impact (FWCI 9.13)OA: greenTopics (42)IDs (PubMed, PMC, OpenAlex)Annotations (4)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (30)

Carleigh A. O’Brien ORCID,Madison Sangster ORCID,Fazeela Yaqoob ORCID,Yuanchao Zhang ORCID,Brian Temsamrit

Live enrichment

PubMed:40311614 PMC:PMC12078009 OpenAlex:https://openalex.org/W4410015032

Alzheimer's Research Trust

Grant: ARUK-SRF2022A-006

National Institutes of Health

Grant: 5T32MH014654

National Institutes of Health

Grant: DP5OD036159

National Institutes of Health

Grant: 5T32MH019112

National Institutes of Health

Grant: P30DK050306

National Institutes of Health National Cancer Institute

Grant: P30 CA016520

Children's Hospital of Philadelphia

Grant: R01-NS-120960

NIMH NIH HHS

Grant: T32 MH019112

NINDS NIH HHS

Grant: R01 NS120960

NIMH NIH HHS

Grant: T32 MH014654

Esther A & Joseph Klingenstein Fund

Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust

University of Pittsburgh

NIHR Newcastle Biomedical Research Centre

National Institute for Health and Care Research

Newcastle University

NIHR Imperial Biomedical Research Centre

The Paul G Allen Frontiers Group

FWCI

9.13

Citation Percentile

1.0%

Citation Trend

2025

2026

greenLicense: http://www.elsevier.com/open-access/userlicense/1.0/

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12078009/

publisherhttps://api.elsevier.com/content/article/PII:S1074761325001384?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1074761325001384?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.immuni.2025.03.019

Fields of Study

Neuroinflammation and Neurodegeneration MechanismsImmune cells in cancerNuclear Receptors and SignalingMicrogliaAnimalsMiceHumansMacrophagesBrainLeukodystrophy, Globoid CellDisease Models, AnimalHematopoietic Stem Cell TransplantationGalactosylceramidaseMice, Inbred C57BLMutation

MeSH Terms

AnimalsBrainDisease Models, AnimalGalactosylceramidaseHumansLeukodystrophy, Globoid CellMacrophagesMice, Inbred C57BLMutationMicrogliaHematopoietic Stem Cell TransplantationMice

Keywords

MicrogliaBiologyDiseaseBrain diseaseImmunologyNeurosciencePathologyInflammationMedicineHematopoietic Stem Cell TransplantKrabbe DiseaseGloboid Cell LeukodystrophyGloboid CellMicroglia ReplacementDisease-associated Macrophage

Sustainable Development Goals

SDG 0: Zero hunger