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To Kill a Microglia: A Case for CSF1R Inhibitors

Trends in Immunology(2020)10.1016/j.it.2020.07.001Source: DataRank Database

To Kill a Microglia: A Case for CSF1R Inhibitors is a research paper published in Trends in Immunology (2020). On theSindex it has a DataRank of 6.2. It has been cited 289 times, with 200 citing works in its 1-hop citation network.

N/A

6.2DataRank · unranked

Scored on demand from live citation data

Open Access289 citations · 200 citing works in its network

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (10 grants)Impact (FWCI 12.59)OA: greenTopics (26)Linked Datasets (25)DataCite Reuse (25)IDs (PubMed, PMC, OpenAlex)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (2/2)

Has DOI
Indexed in repositories

Accessible (1/2)

Open Access

Interoperable (2/2)

DataCite relations
Linked datasets

Reusable (0/3)

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DataRank Breakdown

Base Score 14%Citation Network 86%

Base Score Contribution

0.850

From this paper's citation signal

Citation Network Contribution

5.4

From 190 citing papers with measurable signal

Learn more about DataRank methodology →

Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 200 citers.

Reply to Green and Hume: Nonmicroglia peripheral immune effects of short-term CSF1R inhibition with PLX5622
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Protective Effect of Glucocorticoids against Symptomatic Disease in CSF1R Variant Carriers
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Authors (3)

Joshua Crapser ORCID,Lindsay A. Hohsfield ORCID,Kim N. Green ORCID

Live enrichment

PubMed:32792173 PMC:PMC7484341 OpenAlex:https://openalex.org/W3048341541

NINDS NIH HHS

Grant: F31 NS108611

NIA NIH HHS

Grant: RF1 AG056768

NIA NIH HHS

Grant: P50 AG016573

NINDS NIH HHS

Grant: R01 NS083801

National Institutes of Health

Grant: 5P50AG016573-09

CORE--NEUROPATHOLOGY CORE

National Institutes of Health

Grant: 5F31NS108611-02

Investigating the Role of Microglia in Huntington’s Disease

National Institutes of Health

Grant: 1RF1AG056768-01A1

Microglia are necessary for cortical plaque formation in Alzheimer's disease

National Institutes of Health

Grant: 5R01NS083801-07

Origins, properties, and therapeutic potential of cells that repopulate the microglia-depleted adult brain

Alzheimer's Association

National Institutes of Health

FWCI

12.59

Citation Percentile

1.0%

Citation Trend

2020

2021

2022

2023

2024

2025

2026

greenLicense: Elsevier TDM

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7484341

publisherhttps://api.elsevier.com/content/article/PII:S1471490620301502?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1471490620301502?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.it.2020.07.001

Fields of Study

Neuroinflammation and Neurodegeneration MechanismsImmune cells in cancerChemokine receptors and signaling0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

Central Nervous SystemHumansReceptors, Granulocyte-Macrophage Colony-Stimulating FactorMicroglia

Keywords

MicrogliaImmunologyMedicineBiologyInflammationCentral Nervous SystemBiomedical and Clinical SciencesNeurosciences610Granulocyte-Macrophage Colony-Stimulating FactorPharmacology and Pharmaceutical SciencesReceptors, Granulocyte-Macrophage Colony-Stimulating FactorBiochemistry and cell biologyNeurologicalReceptorsHumans

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being

Additional file 1 of Atg7 deficiency in microglia drives an altered transcriptomic profile associated with an impaired neuroinflammatory response

10.6084/m9.figshare.14728529.v1figshare

Additional file 1 of Atg7 deficiency in microglia drives an altered transcriptomic profile associated with an impaired neuroinflammatory response

10.6084/m9.figshare.14728529figshare

Additional file 1 of The cytokines interleukin-6 and interferon-α induce distinct microglia phenotypes

10.6084/m9.figshare.19608141.v1figshare

Additional file 1 of The cytokines interleukin-6 and interferon-α induce distinct microglia phenotypes

10.6084/m9.figshare.19608141figshare

Additional file 1 of Intermittent theta-burst stimulation improves motor function by inhibiting neuronal pyroptosis and regulating microglial polarization via TLR4/NFκB/NLRP3 signaling pathway in cerebral ischemic mice

10.6084/m9.figshare.20056730.v1figshare

10.6084/m9.figshare.20056730figshare

Additional file 1 of Ablation of microglia does not alter circadian rhythm of locomotor activity

10.6084/m9.figshare.22621774.v1figshare

Additional file 1 of Ablation of microglia does not alter circadian rhythm of locomotor activity

10.6084/m9.figshare.22621774figshare

Additional file 1 of CSF1R regulates schizophrenia-related stress response and vascular association of microglia/macrophages

10.6084/m9.figshare.23884343.v1figshare

Additional file 1 of CSF1R regulates schizophrenia-related stress response and vascular association of microglia/macrophages

10.6084/m9.figshare.23884343figshare

Additional file 2 of CSF1R regulates schizophrenia-related stress response and vascular association of microglia/macrophages

10.6084/m9.figshare.23884346figshare

Additional file 2 of CSF1R regulates schizophrenia-related stress response and vascular association of microglia/macrophages

10.6084/m9.figshare.23884346.v1figshare

Additional file 1 of Microglia preserve visual function loss in the aging retina by supporting retinal pigment epithelial health

10.6084/m9.figshare.24311671.v1figshare

Additional file 1 of Microglia preserve visual function loss in the aging retina by supporting retinal pigment epithelial health

10.6084/m9.figshare.24311671figshare

Additional file 1 of Low-dose PLX5622 treatment prevents neuroinflammatory and neurocognitive sequelae after sepsis

10.6084/m9.figshare.24715481.v1figshare

Additional file 1 of Low-dose PLX5622 treatment prevents neuroinflammatory and neurocognitive sequelae after sepsis

10.6084/m9.figshare.24715481figshare

Additional file 1 of Mas receptor activation facilitates innate hematoma resolution and neurological recovery after hemorrhagic stroke in mice

10.6084/m9.figshare.25687525.v1figshare

Additional file 1 of Mas receptor activation facilitates innate hematoma resolution and neurological recovery after hemorrhagic stroke in mice

10.6084/m9.figshare.25687525figshare

Additional file 7 of CSF1R antagonism results in increased supraspinal infiltration in EAE

10.6084/m9.figshare.26709320.v1figshare

Additional file 8 of CSF1R antagonism results in increased supraspinal infiltration in EAE

10.6084/m9.figshare.26709323.v1figshare

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