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A resistant mutant of Plasmodium falciparum purine nucleoside phosphorylase uses wild-type neighbors to maintain parasite survival

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.100342Source: DataRank Database

A resistant mutant of Plasmodium falciparum purine nucleoside phosphorylase uses wild-type neighbors to maintain parasite survival is a research paper published in Journal of Biological Chemistry (2021). On theSindex it has a DataRank of 0. It has been cited 8 times.

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Open Access8 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (9 grants)OA: goldTopics (38)IDs (PubMed)SDGs (1)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (3)

Rajesh K. Harijan ORCID,Vern L. Schramm ORCID,Yacoba V. T. Minnow ORCID

Live enrichment

PubMed:33524395

National Institutes of Health

Grant: AI127807

National Institutes of Health

Grant: GM041916

National Institutes of Health

Grant: T32 AI070117

National Institutes of Health

Grant: 5R01AI127807-02

PROTOZOAN PURINE PHOSPHORIBOSYLTRANSFERASES AS TARGETS TO TREAT MALARIA, AFRICAN TRYPANOSOMIASIS AND CHAGAS'S DISEASE

National Institutes of Health

Grant: 5R01GM041916-30

Transition State Analysis of Enzymatic Reactions

National Institutes of Health

Grant: 5T32AI070117-11

Geographic Medicine and Emerging Infections

NIAID NIH HHS

Grant: R01 AI127807

NIGMS NIH HHS

Grant: R01 GM041916

NIGMS NIH HHS

Grant: R37 GM041916

goldLicense: cc-by

publisherhttp://www.jbc.org/article/S0021925821001149/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0021925821001149?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0021925821001149?httpAccept=text/plain

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7949152

https://doi.org/10.1016/j.jbc.2021.100342

Fields of Study

0301 basic medicine0303 health sciences03 medical and health sciencesAdenosineAntimalarialsDrug ResistanceHumansMalaria, FalciparumPlasmodium falciparumPoint MutationPurine-Nucleoside PhosphorylasePyrrolidines

MeSH Terms

AdenosineAntimalarialsDrug ResistanceHumansMalaria, FalciparumPlasmodium falciparumPoint MutationPurine-Nucleoside PhosphorylasePyrrolidines

Keywords

AdenosinePyrrolidinesPlasmodium falciparumDrug ResistanceAntimalarialsPurine-Nucleoside PhosphorylaseHumansPoint MutationMalaria, FalciparumResearch ArticleDADMe-ImmGdrug resistance mechanismsenzyme inhibitorenzyme kineticshybrid proteinsprotein engineeringtransition state analog

Sustainable Development Goals

SDG 3: 3. Good health