Vern L. Schramm

ORCID: 0000-0002-8056-1929

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 23 papers. Top paper: “MAT Gain of Activity Mutation in Helicobacter pylori Is Associated with Resistance to MTAN Transition State Analogues”.

MAT Gain of Activity Mutation in Helicobacter pylori Is Associated with Resistance to MTAN Transition State Analogues

ACS Infectious Diseases(2023)10.1021/acsinfecdis.2c00644

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0.269DataRank · unranked

5 citations

Hilda A. Namanja-Magliano, Rajagopalan Saranathan, Tanmay Mishra, Rodrigo G. Ducati, Brett M. Hirsch +8 more

Transition-State Analogues of Phenylethanolamine N-Methyltransferase

Journal of the American Chemical Society(2020)10.1021/jacs.0c05446

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28 citations

Rajesh K. Harijan, Vern L. Schramm, Niusha Mahmoodi

Determinants of sensitivity of human T-cell leukemia CCRF-CEM cells to immucillin-H

UNC Libraries(2020)10.17615/b61m-g863

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0DataRank · unranked

0 citations

Min Huang, Karen Noel, Jing Yang, Beverly S. Mitchell, Jingjin Gu +3 more

Inhibition of Clostridium difficile TcdA and TcdB toxins with transition state analogues

Nature Communications(2021)10.1038/s41467-021-26580-6

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35 citations

Briana L. Aboulache, Rajesh K. Harijan, Kathryn Potts, Peter C. Tyler, Vern L. Schramm +1 more

Mechanism and Inhibition of Human Methionine Adenosyltransferase 2A

Biochemistry(2021)10.1021/acs.biochem.0c00998

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16 citations

Agnidipta Ghosh, Sean M. Cahill, Vern L. Schramm, Courtney N. Niland

Transition state analogue of MTAP extends lifespan of APCMin/+ mice

Scientific Reports(2021)10.1038/s41598-021-87734-6

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16 citations

Mu Feng, Indranil Basu, Karina Peregrina, Leonard H. Augenlicht, Vern L. Schramm +1 more

Aminofutalosine Deaminase in the Menaquinone Pathway of Helicobacter pylori

Biochemistry(2021)10.1021/acs.biochem.1c00215

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6 citations

Rajesh K. Harijan, Lawrence D. Harris, Peter C. Tyler, Richard Fröhlich, Morais Brown +2 more

A resistant mutant of Plasmodium falciparum purine nucleoside phosphorylase uses wild-type neighbors to maintain parasite survival

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.100342

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0DataRank · unranked

8 citations

Rajesh K. Harijan, Vern L. Schramm, Yacoba V. T. Minnow

Mechanism of Triphosphate Hydrolysis by Human MAT2A at 1.07 Å Resolution

Journal of the American Chemical Society(2021)10.1021/jacs.1c09328

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4 citations

Courtney N. Niland, Sean M. Cahill, Nishant M. Karadkhelkar, Vern L. Schramm, Agnidipta Ghosh

Inhibition and Mechanism of Plasmodium falciparum Hypoxanthine–Guanine–Xanthine Phosphoribosyltransferase

ACS Chemical Biology(2022)10.1021/acschembio.2c00546

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0DataRank · unranked

8 citations

Kajitha Suthagar, Keith Clinch, Rodrigo G. Ducati, Agnidipta Ghosh, Joshua N. Buckler +5 more

The design of protozoan phosphoribosyltransferase inhibitors containing non-charged phosphate mimic residues

Bioorganic & Medicinal Chemistry(2022)10.1016/j.bmc.2022.117038

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0DataRank · unranked

2 citations

Kajitha Suthagar, Karl J. Shaffer, Wanting Jiao, Yacoba V. T. Minnow, Kayla Glockzin +6 more

Combined inhibition of MTAP and MAT2a mimics synthetic lethality in tumor models via PRMT5 inhibition

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.105492

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31 citations

Nord Gilaj, Karina Peregrina, Isabella Brew, Elena Tosti, Karl J. Shaffer +5 more

Residence Times for Femtomolar and Picomolar Inhibitors of MTANs

Biochemistry(2023)10.1021/acs.biochem.3c00145

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2 citations

Peter C. Tyler, Vern L. Schramm, Morais Brown

An enzyme-coupled microplate assay for activity and inhibition of hmdUMP hydrolysis by DNPH1

Analytical Biochemistry(2023)10.1016/j.ab.2023.115171

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5 citations

Roozbeh Eskandari, Vern L. Schramm, Andrew G. Wagner

Phosphate Binding in PNP Alters Transition-State Analogue Affinity and Subunit Cooperativity

Biochemistry(2023)10.1021/acs.biochem.3c00264

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2 citations

Vern L. Schramm, Steven C. Almo, Agnidipta Ghosh, Yacoba V. T. Minnow

Cell-Effective Transition-State Analogue of Phenylethanolamine N-Methyltransferase

Biochemistry(2023)10.1021/acs.biochem.3c00103

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2 citations

Yacoba V. T. Minnow, Rajesh K. Harijan, Gabriel T. Bedard, Vern L. Schramm, Niusha Mahmoodi

Isofagomine inhibits multiple TcdB variants and protects mice from Clostridioides difficile induced mortality

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.19.558375

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0DataRank · unranked

0 citations

Isabella Brew, Huynh A. Hong, William Ferriera, Simon M. Cutting, Farah Oulaïdi +4 more

Decreased Transition-State Analogue Affinity in Isotopically Heavy MTAN with Increased Catalysis

Biochemistry(2023)10.1021/acs.biochem.3c00434

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0 citations

Vern L. Schramm, Morais Brown

Transition State Analogs of Human DNPH1 Reveal Two Electrophile Migration Mechanisms

Journal of Medicinal Chemistry(2025)10.1021/acs.jmedchem.4c02778

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0DataRank · unranked

8 citations

Thomas B. D. Lang, Edward T. Ledingham, Agnidipta Ghosh, Donovan Brooks, Roozbeh Eskandari +6 more

Transition State Analysis of SAMHD1 from Primary 18O, 33P, and Solvent Kinetic Isotope Effects

Journal of the American Chemical Society(2025)10.1021/jacs.5c00521

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3 citations

D. Groom, Vern L. Schramm, Ananda K. Ghosh

Kinetic Mechanism of the Emergent Anticancer Target, Human ADP-ribosyltransferase 1

Biochemistry(2025)10.1021/acs.biochem.5c00105

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1 citations

Amanda Lopacinski, S. Garforth, Vern L. Schramm, D. Groom

Small Molecule Inhibitors Targeting the Interaction of Ricin Toxin A Subunit with Ribosomes

ACS Infectious Diseases(2020)10.1021/acsinfecdis.0c00127

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0DataRank · unranked

20 citations

Rajesh K. Harijan, Jennifer Nielsen Kahn, Vern L. Schramm, Nilgun E. Tumer, Xiaoping Li

Continuous assay for the dNTP triphosphohydrolase of activated SAMHD1

Analytical Biochemistry(2025)10.1016/j.ab.2025.115966

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0DataRank · unranked

0 citations

D. Groom, Ryo Tamura, Vern L. Schramm, Roozbeh Eskandari