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Major advances in targeted protein degradation: PROTACs, LYTACs, and MADTACs

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.100647Source: DataRank Database

Major advances in targeted protein degradation: PROTACs, LYTACs, and MADTACs is a research paper published in Journal of Biological Chemistry (2021). On theSindex it has a DataRank of 0. It has been cited 259 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access259 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (4 grants)Impact (FWCI 12.90)OA: goldTopics (31)IDs (PubMed, PMC, OpenAlex)Annotations (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (2)

Craig M. Crews ORCID,Shanique Alabi ORCID

Live enrichment

PubMed:33839157 PMC:PMC8131913 OpenAlex:https://openalex.org/W3153520238

NCI NIH HHS

Grant: R35 CA197589

National Institutes of Health

Grant: 5R35CA197589-11

Inducing Proximity: An Emerging Paradigm for New Therapeutic Modalities

Howard Hughes Medical Institute

National Institutes of Health

FWCI

12.90

Citation Percentile

1.0%

Citation Trend

2021

2022

2023

2024

2025

2026

goldLicense: cc-by

journalhttp://www.jbc.org/article/S0021925821004336/pdf

publisherhttp://www.jbc.org/article/S0021925821004336/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0021925821004336?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0021925821004336?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.jbc.2021.100647

Fields of Study

Protein Degradation and InhibitorsUbiquitin and proteasome pathwaysPeptidase Inhibition and Analysis0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

LysosomesProteinsProteasome Endopeptidase ComplexUbiquitinationProteolysis

Keywords

Degradation (telecommunications)Protein degradationComputational biologyBiologyEngineeringCell biologyTelecommunicationsUbiquitinationLysosomeDrug actionChemical BiologyProtacsMolecular GluesAutacsLytacsProteasome Endopeptidase ComplexJBC ReviewsProteolysisProteinsLysosomes

Major advances in targeted protein degradation: PROTACs, LYTACs, and MADTACs

FAIR Checklist

Authors (2)

Funding (4 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)