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Prolonged deprivation of arginine or leucine induces PI3K/Akt-dependent reactivation of mTORC1

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.102030Source: DataRank Database

Prolonged deprivation of arginine or leucine induces PI3K/Akt-dependent reactivation of mTORC1 is a research paper published in Journal of Biological Chemistry (2022). On theSindex it has a DataRank of 0.505. It has been cited 28 times.

N/A

0.505DataRank · unranked

Scored on demand from live citation data

Open Access28 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (6 grants)Impact (FWCI 1.72)OA: goldTopics (47)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 100%Citation Network 0%

Base Score Contribution

0.505

From this paper's citation signal

Citation Network Contribution

Citation network not refreshed for this result

This paper's DataRank is currently driven only by its base citation score. Citation network data was not refreshed for this result.

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Authors (5)

Huy Q. Dang,John M. Asara ORCID,John Blenis ORCID,Anders P. Mutvei ORCID,Gwen R. Buel ORCID

Live enrichment

PubMed:35577075 OpenAlex:https://openalex.org/W4280515880

National Institutes of Health

Grant: F31 CA173942

National Institutes of Health

Grant: R01 GM051405

Vetenskapsrådet

Grant: 2020-01126

National Institutes of Health

Grant: 1F31CA173942-01

mTORC1 Regulation by Amino Acids

Swedish Cancer Society

Grant: unidentified

unidentified

National Institutes of Health

Grant: 2R01GM051405-13

Signal Transduction to p70 S6 Kinase 1

FWCI

1.72

Citation Percentile

0.8%

Citation Trend

2022

2023

2024

2025

2026

goldLicense: cc-by

journalhttp://www.jbc.org/article/S0021925822004707/pdf

publisherhttp://www.jbc.org/article/S0021925822004707/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0021925822004707?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0021925822004707?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.jbc.2022.102030

Fields of Study

PI3K/AKT/mTOR signaling in cancerPolyamine Metabolism and ApplicationsAutophagy in Disease and Therapy0301 basic medicine0303 health sciences03 medical and health sciencesAmino AcidsAnimalsArginineLeucineMechanistic Target of Rapamycin Complex 1MicePhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-akt

MeSH Terms

Mechanistic Target of Rapamycin Complex 1Amino AcidsAnimalsArginineLeucinePhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktMice

Keywords

mTORC1PI3K/AKT/mTOR pathwayLeucineAmino acidProtein kinase BArginineCell biologyRHEBBiochemistryBiologySignal transductionCrosstalkPhosphorylationChemistryCellbiologiMechanistic Target of Rapamycin Complex 1MicePhosphatidylinositol 3-KinasesAnimalsAmino AcidsProto-Oncogene Proteins c-aktResearch ArticleAktsignalingstarvation

Sustainable Development Goals

SDG 2: 2. Zero hunger