John M. Asara

Also affiliated with Harvard University, Cancer Research Institute, Hadassah Medical Center, Harvard University Press

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 108 papers. Top paper: “GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis”.

GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis

Nature Communications(2021)10.1038/s41467-021-24859-2

N/A

6.7DataRank · unranked

258 citations

Barbara Scott Nelson, Lin Lin, Emily L. Yarosz, Christopher J. Halbrook, Samuel A. Kerk +29 more

The mTORC1-mediated activation of ATF4 promotes protein and glutathione synthesis downstream of growth signals

eLife(2021)10.7554/elife.63326

N/A

4.1DataRank · unranked

250 citations

Michael R. MacArthur, Aaron M. Hosios, Alexander J. Valvezan, John M. Asara, James R. Mitchell +2 more

Homozygous MTAP deletion in primary human glioblastoma is not associated with elevation of methylthioadenosine

Nature Communications(2021)10.1038/s41467-021-24240-3

N/A

2.2DataRank · unranked

55 citations

Jeffrey J. Ackroyd, Victoria C. Yan, Sunada Khadka, Lin Wang, Ko‐Chien Chen +16 more

PARP-inhibition reprograms macrophages toward an anti-tumor phenotype

Cell Reports(2022)10.1016/j.celrep.2022.111462

N/A

1.1DataRank · unranked

57 citations

Dan Wang, Olmo Sonzogni, Shizhong Ke, Qi Wang, Abhishek Thavamani +17 more

A label‐free quantification method by MS/MS TIC compared to SILAC and spectral counting in a proteomics screen

PROTEOMICS(2008)10.1002/pmic.200700426

N/A

0.812DataRank · unranked

223 citations

Heather R. Christofk, Lisa M. Freimark, Lewis C. Cantley, John M. Asara

AMPK/ULK1-mediated phosphorylation of Parkin ACT domain mediates an early step in mitophagy

Science Advances(2021)10.1126/sciadv.abg4544

N/A

0.763DataRank · unranked

161 citations

Portia S. Lombardo, Nazma Malik, Sonja N. Brun, Kristina Hellberg, Jeanine L. Van Nostrand +6 more

SHP-2 and PD-1-SHP-2 signaling regulate myeloid cell differentiation and antitumor responses

Nature Immunology(2022)10.1038/s41590-022-01385-x

N/A

0.675DataRank · unranked

89 citations

Xanthi-Lida Katopodi, Carol Cao, Dimitra Karagkouni, Konstantinos Aliazis, Sasitorn Yenyuwadee +11 more

De Novo Pyrimidine Synthesis is a Targetable Vulnerability in IDH Mutant Glioma

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.11.30.470443

N/A

0.611DataRank · unranked

11 citations

Milan R. Savani, Michael M. Levitt, Adam C. Wang, Jennifer E. Endress, Cylaina Bird +38 more

Downregulation of the tyrosine degradation pathway extends Drosophila lifespan

eLife(2020)10.7554/elife.58053

N/A

0.593DataRank · unranked

51 citations

Divya Ramesh, Lin Wang, Dmitry Leshchiner, Elizabeth Filine, Richard Binari +7 more

A phosphate-sensing organelle regulates phosphate and tissue homeostasis

Nature(2023)10.1038/s41586-023-06039-y

N/A

0.578DataRank · unranked

46 citations

Jun Xu, Hong-Wen Tang, Maria Ericsson, Jui–Hsia Weng, Jonathan DiRusso +5 more

DHODH modulates immune evasion of cancer cells via CDP-Choline dependent regulation of phospholipid metabolism and ferroptosis

Nature Communications(2025)10.1038/s41467-025-59307-y

N/A

0.566DataRank · unranked

16 citations

Kenneth D. Swanson, Ruiheng Wang, Aojia Zhuang, Haofeng Wu, Zhixin Niu +7 more

Impaired anaplerosis is a major contributor to glycolysis inhibitor toxicity in glioma

Cancer & Metabolism(2021)10.1186/s40170-021-00259-4

N/A

0.483DataRank · unranked

24 citations

Kenisha Arthur, Yasaman Barekatain, Eliot Behr, M. K. Washington, Jeffrey J. Ackroyd +11 more

Inactivation of adenosine receptor 2A suppresses endothelial-to-mesenchymal transition and inhibits subretinal fibrosis in mice

Science Translational Medicine(2024)10.1126/scitranslmed.adk3868

N/A

0.457DataRank · unranked

20 citations

Yongfeng Cai, Qian Ma, Albert Xiong, P.T. Xu, Zhidan Zhang +11 more

Metabolic and Functional Genomic Studies Identify Deoxythymidylate Kinase as a Target in LKB1-Mutant Lung Cancer

UNC Libraries(2020)10.17615/ge7q-0q17

N/A

0.442DataRank · unranked

18 citations

Sean T. Bailey, David J. Kwiatkowski, Pasi A. Jänne, Jeffrey A. Engelman, Julián Carretero +35 more

The mTORC1-mediated activation of ATF4 promotes protein and glutathione synthesis downstream of growth signals

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.10.03.324186

N/A

0.425DataRank · unranked

16 citations

Michael R. MacArthur, Aaron M. Hosios, Alexander J. Valvezan, John M. Asara, James R. Mitchell +2 more

HHIP protein interactions in lung cells provide insight into COPD pathogenesis

Human Molecular Genetics(2025)10.1093/hmg/ddaf016

N/A

0.208DataRank · unranked

3 citations

Hiroyuki Inuzuka, Peter J. Castaldi, Jeong H. Yun, Zhonghui Xu, Wardatul Jannat Anamika +7 more

1.11 Integrative Genomic Analysis Implicates PIK3CA and MYC in Chronic Lymphocytic Leukemia

Clinical Lymphoma Myeloma and Leukemia(2011)10.1016/j.clml.2011.09.012

N/A

0.133DataRank · unranked

1 citations

Megan Hanna, Bethany Tesar, Lillian Werner, Nathalie Pochet, John M. Asara +13 more

Proteomics of protein trafficking by in vivo tissue-specific labeling

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.15.039933

N/A

0DataRank · unranked

4 citations

Dan Wang, Yanhui Hu, Namrata D. Udeshi, Luye Mu, Tanya Svinkina +9 more

GOT1 Inhibition Primes Pancreatic Cancer for Ferroptosis through the Autophagic Release of Labile Iron

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.02.28.970228

N/A

0DataRank · unranked

3 citations

Barbara Scott Nelson, Lin Lin, Emily L. Yarosz, Christopher J. Halbrook, Samuel A. Kerk +22 more

Age-induced methylmalonic acid accumulation promotes tumor progression and aggressiveness

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.04.135087

N/A

0DataRank · unranked

1 citations

Didem Ilter, Vivien Low, Jennifer E. Endress, Juan Fernández-García, Adam Rosenzweig +16 more

Fatty acid synthesis is required for breast cancer brain metastasis

Nature Cancer(2021)10.1038/s43018-021-00183-y

N/A

0DataRank · unranked

325 citations

Ahmed Ali, Alba Luengo, David P. Kodack, Amy Deik, Keene L. Abbott +31 more

mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis

Molecular Cell(2021)10.1016/j.molcel.2021.03.009

N/A

0DataRank · unranked

179 citations

Umakant Sahu, Brendan P. O’Hara, Eunüs S. Ali, Kathryn A. Helmin, John M. Asara +4 more

Proteomics of protein trafficking by in vivo tissue-specific labeling

Nature Communications(2021)10.1038/s41467-021-22599-x

N/A

0DataRank · unranked

118 citations

Amanda S. Meyer, Dan Wang, Namrata D. Udeshi, Yanhui Hu, David Rocco +16 more

mTORC1-chaperonin CCT signaling regulates m 6 A RNA methylation to suppress autophagy

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2021945118

N/A

0DataRank · unranked

73 citations

Jui–Hsia Weng, Wen Xing Lee, Yanhui Hu, Lei Gu, Sungyun Cho +12 more

Interplay between protein acetylation and ubiquitination controls MCL1 protein stability

Cell Reports(2021)10.1016/j.celrep.2021.109988

N/A

0DataRank · unranked

61 citations

Min Gi, Shugo Suzuki, Brian J. North, Asami Watahiki, Satoshi Fukumoto +5 more

Targeted metabolomics analysis of postoperative delirium

Scientific Reports(2021)10.1038/s41598-020-80412-z

N/A

0DataRank · unranked

55 citations

Simon T. Dillon, Min Yuan, John M. Asara, Sarinnapha M. Vasunilashorn, Tamara G. Fong +8 more

A genetic model of methionine restriction extends Drosophila health- and lifespan

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2110387118

N/A

0DataRank · unranked

49 citations

Lin Wang, Elizabeth Filine, Patrick Jouandin, Dmitry Leshchiner, Richard Binari +4 more

NADK is activated by oncogenic signaling to sustain pancreatic ductal adenocarcinoma

Cell Reports(2021)10.1016/j.celrep.2021.109238

N/A

0DataRank · unranked

41 citations

Melanie R. McReynolds, Christie Shea, Vivien Low, Bethany E. Schaffer, John M. Asara +6 more

Hepatic mTORC1 signaling activates ATF4 as part of its metabolic response to feeding and insulin

Molecular Metabolism(2021)10.1016/j.molmet.2021.101309

N/A

0DataRank · unranked

37 citations

Yann Cormerais, Krystle C. Kalafut, Víctor Barrera, James E Hughes Hallett, Shannan Ho Sui +6 more

Therapeutic Targeting of DGKA-Mediated Macropinocytosis Leads to Phospholipid Reprogramming in Tuberous Sclerosis Complex

Cancer Research(2021)10.1158/0008-5472.can-20-2218

N/A

0DataRank · unranked

14 citations

Andres Sanin, Kosmas Kosmas, Long Zhang, Ji Wang, Elie W. Akl +11 more

Comparative Untargeted Metabolomic Profiling of Induced Mitochondrial Fusion in Pancreatic Cancer

Metabolites(2021)10.3390/metabo11090627

N/A

0DataRank · unranked

5 citations

Meifang Yu, Vinit Y. Reddy, Ariana Carolina Acevedo-Diaz, Enzo C. Mesarick, Joseph Abi Jaoude +4 more

Hepatic mTORC1 signaling activates ATF4 as part of its metabolic response to feeding and insulin

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.05.02.442369

N/A

0DataRank · unranked

4 citations

Yann Cormerais, Krystle C. Kalafut, Víctor Barrera, James E Hughes Hallett, Shannan Ho Sui +6 more

Comparative untargeted metabolomic profiling of induced mitochondrial fusion in pancreatic cancer

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.08.06.455450

N/A

0DataRank · unranked

2 citations

Meifang Yu, Vinit Y. Reddy, Ariana Acevedo-Diaz, Enzo C. Mesarick, Joseph Abi Jaoude +4 more

Interleukin-6 mediates PSAT1 expression and serine metabolism in TSC2-deficient cells

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.05.17.444471

N/A

0DataRank · unranked

1 citations

Harilaos Filippakis, Thomas R. Hougard, Heng Du, Chenyang Ye, Heng-Jia Liu +10 more

Non-conserved metabolic regulation by LKB1 distinguishes human and mouse lung adenocarcinoma

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.01.462764

N/A

0DataRank · unranked

1 citations

John R. Ferrarone, Eric E. Gardner, Jae Won Chang, David Wu, Qiuying Chen +13 more

A local tumor microenvironment acquired super-enhancer induces an oncogenic driver for efficient growth under oxidative conditions in colorectal carcinoma

Research Square(2021)10.21203/rs.3.rs-799320/v1

N/A

0DataRank · unranked

0 citations

Jia Xu, Tiphaine Martin, Sait Öztürk, Alexis L. Zachem, John Cijiang He +21 more

Myeloid-derived itaconate suppresses cytotoxic CD8+ T cells and promotes tumour growth

Nature Metabolism(2022)10.1038/s42255-022-00676-9

N/A

0DataRank · unranked

165 citations

Da Teng, Lifeng Yang, Xincheng Xu, Jiajia Chen, Teng‐Jia Jiang +14 more

De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma

Cancer Cell(2022)10.1016/j.ccell.2022.07.011

N/A

0DataRank · unranked

131 citations

Milan R. Savani, Michael M. Levitt, Adam C. Wang, Jennifer E. Endress, Cylaina Bird +46 more

Altered propionate metabolism contributes to tumour progression and aggressiveness

Nature Metabolism(2022)10.1038/s42255-022-00553-5

N/A

0DataRank · unranked

113 citations

Didem Ilter, Vivien Low, Stanislav Drápela, Tanya Schild, Edouard Mullarky +13 more

PI3K drives the de novo synthesis of coenzyme A from vitamin B5

Nature(2022)10.1038/s41586-022-04984-8

N/A

0DataRank · unranked

100 citations

Samuel A. Barritt, Grace E. Perry, Evan C. Lien, Renee C. Geck, Sarah DuBois-Coyne +11 more

Purine nucleotide depletion prompts cell migration by stimulating the serine synthesis pathway

Nature Communications(2022)10.1038/s41467-022-30362-z

N/A

0DataRank · unranked

86 citations

R. Kesavan, Umakant Sahu, Alpaslan Tasdogan, Elodie Villa, Zied Djabari +16 more

A local tumor microenvironment acquired super-enhancer induces an oncogenic driver in colorectal carcinoma

Nature Communications(2022)10.1038/s41467-022-33377-8

N/A

0DataRank · unranked

46 citations

Jia Xu, Tiphaine Martin, Alexis L. Zachem, John Cijiang He, Sait Öztürk +22 more

The mTORC1-SLC4A7 axis stimulates bicarbonate import to enhance de novo nucleotide synthesis

Molecular Cell(2022)10.1016/j.molcel.2022.06.008

N/A

0DataRank · unranked

41 citations

Anna Lipońska, Brendan P. O’Hara, David R. Amici, Michael D. Torno, Peng Gao +5 more

Prolonged deprivation of arginine or leucine induces PI3K/Akt-dependent reactivation of mTORC1

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.102030

N/A

0DataRank · unranked

28 citations

Huy Q. Dang, John M. Asara, John Blenis, Anders P. Mutvei, Gwen R. Buel

Vibrio cholerae high cell density quorum sensing activates the host intestinal innate immune response

Cell Reports(2022)10.1016/j.celrep.2022.111368

N/A

0DataRank · unranked

30 citations

Juliana H. Batista, J A Gibson, Paul Cunningham, John M. Asara, Paula I. Watnick +1 more

MicroRNA-21 guide and passenger strand regulation of adenylosuccinate lyase-mediated purine metabolism promotes transition to an EGFR-TKI-tolerant persister state

Cancer Gene Therapy(2022)10.1038/s41417-022-00504-y

N/A

0DataRank · unranked

19 citations

Nicholas Skiados, Fareesa Aftab, Cerena Moreno, Luis Silva, Paul Joshua Anthony Corbilla +4 more

Trans-omics analysis of insulin action reveals a cell growth subnetwork which co-regulates anabolic processes

iScience(2022)10.1016/j.isci.2022.104231

N/A

0DataRank · unranked

11 citations

Yanhui Hu, Toshiya Kokaji, Katsuyuki Yugi, Keigo Morita, Satoshi Ohno +9 more

NAD+ biosynthesis as a collateral lethality target for precision oncology

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.12.13.518967

N/A

0DataRank · unranked

1 citations

Pingna Deng, Yu-Hsi Lin, Nikunj Satani, Naima Hammoudi, Gayatry Mohapatra +3 more

SHP-2 and canonical PD-1: SHP-2 axis regulate myeloid cell differentiation, anti-tumor responses and innate immune memory

Research Square(2022)10.21203/rs.3.rs-1198158/v1

N/A

0DataRank · unranked

0 citations

Anthos Christofides, Xanthi-Lida Katopodi, Carol Cao, Halil‐Ibrahim Aksoylar, Mohamed A. A. Mahmoud +8 more

Metabolic orchestration of cell death by AMPK-mediated phosphorylation of RIPK1

Science(2023)10.1126/science.abn1725

N/A

0DataRank · unranked

123 citations

Daichao Xu, Elijah Trefts, Mingming Lv, Hiroyuki Inuzuka, Guobin Song +35 more

RB1-deficient prostate tumor growth and metastasis are vulnerable to ferroptosis induction via the E2F/ACSL4 axis

Journal of Clinical Investigation(2023)10.1172/jci166647

N/A

0DataRank · unranked

106 citations

Jiaqi Chen, Yi Lu, Alyssa Bawcom, Jinjin Wu, Jianhong Ou +8 more

AKT activation because of PTEN loss upregulates xCT via GSK3β/NRF2, leading to inhibition of ferroptosis in PTEN-mutant tumor cells

Cell Reports(2023)10.1016/j.celrep.2023.112536

N/A

0DataRank · unranked

51 citations

Abigail Lubin, Kaitlyn Bosch, Nicole Stokes, Sarah Mense Shoenfeld, Royce Zhou +4 more

Cytosolic aldose metabolism contributes to progression from cirrhosis to hepatocarcinogenesis

Nature Metabolism(2023)10.1038/s42255-022-00711-9

N/A

0DataRank · unranked

45 citations

Akshay Patel, Nick Huang, G. Choudhary, Thomas Winans, Tamás Faludi +14 more

AMPK-dependent phosphorylation of the GATOR2 component WDR24 suppresses glucose-mediated mTORC1 activation

Nature Metabolism(2023)10.1038/s42255-022-00732-4

N/A

0DataRank · unranked

41 citations

Cong Jiang, Qiwei Jiang, Lan Fang, Haihong Yu, Jinhe Guo +9 more

LKB1-Dependent Regulation of TPI1 Creates a Divergent Metabolic Liability between Human and Mouse Lung Adenocarcinoma

Cancer Discovery(2023)10.1158/2159-8290.cd-22-0805

N/A

0DataRank · unranked

39 citations

John R. Ferrarone, Eric E. Gardner, Jae Won Chang, David Wu, Pablo E. Hollstein +14 more

PRMT1 orchestrates with SAMTOR to govern mTORC1 methionine sensing via Arg-methylation of NPRL2

Cell Metabolism(2023)10.1016/j.cmet.2023.11.001

N/A

0DataRank · unranked

39 citations

Jing Liu, Shaohui He, Wei Xu, Runzhi Huang, Weijuan Pan +10 more

mTOR-dependent loss of PON1 secretion and antiphospholipid autoantibody production underlie autoimmunity-mediated cirrhosis in transaldolase deficiency

Journal of Autoimmunity(2023)10.1016/j.jaut.2023.103112

N/A

0DataRank · unranked

38 citations

Zachary Oaks, G. Choudhary, Akshay Patel, Nick Huang, Tamás Faludi +14 more

NADK-mediated de novo NADP(H) synthesis is a metabolic adaptation essential for breast cancer metastasis

Redox Biology(2023)10.1016/j.redox.2023.102627

N/A

0DataRank · unranked

34 citations

Stanislav Drápela, Tanya Schild, Nathan P. Ward, Emma Adhikari, Vivien Low +7 more

Purine synthesis suppression reduces the development and progression of pulmonary hypertension in rodent models

European Heart Journal(2023)10.1093/eurheartj/ehad044

N/A

0DataRank · unranked

29 citations

Qiuhua Yang, Jiean Xu, Hunter Sellers, Zachary Brown, Zhiping Liu +20 more

Myeloid PFKFB3-mediated glycolysis promotes kidney fibrosis

Frontiers in Immunology(2023)10.3389/fimmu.2023.1259434

N/A

0DataRank · unranked

26 citations

Emily Huo, Yongfeng Cai, Zhidan Zhang, Charles Dong, John M. Asara +3 more

Nuclear PTEN Regulates Thymidylate Biosynthesis in Human Prostate Cancer Cell Lines

Metabolites(2023)10.3390/metabo13080939

N/A

0DataRank · unranked

4 citations

Mu‐En Wang, Changxin Wan, John M. Asara, Zhicheng Ji, Ming Chen +1 more

Pro-905, a Novel Purine Antimetabolite, Combines with Glutamine Amidotransferase Inhibition to Suppress Growth of Malignant Peripheral Nerve Sheath Tumor

Molecular Cancer Therapeutics(2023)10.1158/1535-7163.mct-23-0258

N/A

0DataRank · unranked

2 citations

Eunüs S. Ali, Marcela Krečmerová, Joanna Marie H. Aguilar, Jesse Alt, Diane E. Peters +11 more

Lysine vitcylation is a novel vitamin C-derived protein modification that enhances STAT1-mediated immune response

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.27.546774

N/A

0DataRank · unranked

3 citations

Yun Wei, Jiang Wu, Qiwei Wang, Johann S. Bergholz, Hao Gu +11 more

Data from Therapeutic Targeting of DGKA-Mediated Macropinocytosis Leads to Phospholipid Reprogramming in Tuberous Sclerosis Complex

(2023)10.1158/0008-5472.c.6513499.v1

N/A

0DataRank · unranked

0 citations

Andres Sanin, Kosmas Kosmas, Long Zhang, Ji Wang, Elie W. Akl +11 more

Data from Therapeutic Targeting of DGKA-Mediated Macropinocytosis Leads to Phospholipid Reprogramming in Tuberous Sclerosis Complex

(2023)10.1158/0008-5472.c.6513499

N/A

0DataRank · unranked

0 citations

Andres Sanin, Kosmas Kosmas, Long Zhang, Ji Wang, Elie W. Akl +11 more

Data from LKB1-Dependent Regulation of TPI1 Creates a Divergent Metabolic Liability between Human and Mouse Lung Adenocarcinoma

(2023)10.1158/2159-8290.c.6534613.v2

N/A

0DataRank · unranked

0 citations

John R. Ferrarone, Eric E. Gardner, Jae Won Chang, David Wu, Pablo E. Hollstein +14 more

Anaplerotic nutrient stress drives synergy of angiogenesis inhibitors with therapeutics targeting tumor metabolism

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.05.07.539744

N/A

0DataRank · unranked

0 citations

Yu-Hsi Lin, Jeffrey J. Ackroyd, Yi‐An Chen, Yanghui Sheng, Wubin Qian +19 more

Anaplerotic nutrient stress drives synergy of angiogenesis inhibitors with therapeutics targeting tumor metabolism

Research Square(2023)10.21203/rs.3.rs-2987360/v1

N/A

0DataRank · unranked

0 citations

Yu-Hsi Lin, Jeffrey J. Ackroyd, Yi‐An Chen, Yanghui Sheng, Wubin Qian +19 more

Pyrimidines maintain mitochondrial pyruvate oxidation to support de novo lipogenesis

Science(2024)10.1126/science.adh2771

N/A

0DataRank · unranked

70 citations

Elodie Villa, Colleen R. Reczek, Zibo Zhao, Brendan P. O’Hara, Michael D. Torno +8 more

IDH1 Inhibition Potentiates Chemotherapy Efficacy in Pancreatic Cancer

Cancer Research(2024)10.1158/0008-5472.can-23-1895

N/A

0DataRank · unranked

25 citations

Omid Hajihassani, Jonathan J. Hue, Alexander W. Loftus, Hallie J. Graor, Faith Nakazzi +10 more

Methylmalonic acid induces metabolic abnormalities and exhaustion in CD8+ T cells to suppress anti-tumor immunity

Oncogene(2024)10.1038/s41388-024-03191-1

N/A

0DataRank · unranked

20 citations

Rebecca S. Hesterberg, Stanislav Drápela, Didem Ilter, Devesh Raizada, Felicia Lazure +10 more

In vivo Bruton’s tyrosine kinase inhibition attenuates alcohol-associated liver disease by regulating CD84-mediated granulopoiesis

Science Translational Medicine(2024)10.1126/scitranslmed.adg1915

N/A

0DataRank · unranked

8 citations

Yeonhee Cho, Yuan Zhuang, Mrigya Babuta, Martí Ortega‐Ribera, Radhika Joshi +23 more

Integrated Multi-Omics Analysis of Cerebrospinal Fluid in Postoperative Delirium

Biomolecules(2024)10.3390/biom14080924

N/A

0DataRank · unranked

6 citations

Simon T. Dillon, Min Yuan, John M. Asara, Sarinnapha M. Vasunilashorn, Tamara G. Fong +7 more

Unique tau‐ and synuclein‐dependent metabolic reprogramming in neurons distinct from normal aging

Aging Cell(2024)10.1111/acel.14277

N/A

0DataRank · unranked

6 citations

Aidan Graham, Farazdaq Al hammood, Chris Garbark, Deepika Vasudevan, Udai Bhan Pandey +4 more

Parallel phosphoproteomics and metabolomics map the global metabolic tyrosine phosphoproteome

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2413837121

N/A

0DataRank · unranked

6 citations

Tigist Y. Tamir, Grace E. Perry, John M. Asara, Jared L. Johnson, Tomer M. Yaron +4 more

A carboxy-terminal ubiquitylation site regulates androgen receptor activity

Communications Biology(2024)10.1038/s42003-023-05709-x

N/A

0DataRank · unranked

4 citations

Yanfei Gao, Ziyang Yu, Lisha Xie, Liyang Wang, Tengfei Zhang +5 more

Derangement in Nicotinamide Adenine Dinucleotide Metabolism is Observed During Acute Kidney Injury Among Male Agricultural Workers at Risk for Mesoamerican Nephropathy

Kidney International Reports(2024)10.1016/j.ekir.2024.04.027

N/A

0DataRank · unranked

1 citations

Dominic Leone, Juan José Amador, Damaris López-Pilarte, Oriana Ramírez‐Rubio, Iris Delgado +8 more

The CTLH Ubiquitin Ligase Substrates ZMYND19 and MKLN1 Negatively Regulate mTORC1 at the Lysosomal Membrane

Research Square(2024)10.21203/rs.3.rs-4259395/v1

N/A

0DataRank · unranked

4 citations

Rui Guo, Brenda Iturbide Piedras, Hsin‐Yao Tang, John M. Asara, Italo Tempera +3 more

Multi-omic Analysis of Human B-cell Activation Reveals a Key Lysosomal BCAT1 Role in mTOR Hyperactivation by B-cell receptor and TLR9

Research Square(2024)10.21203/rs.3.rs-4413958/v1

N/A

0DataRank · unranked

2 citations

Matthew Lim, Hardik Shah, Joao A. Paulo, Yuchen Zhang, Haopeng Yang +18 more

Methylmalonic acid induces metabolic abnormalities and exhaustion in CD8 + T cells to suppress anti-tumor immunity

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.03.583124

N/A

0DataRank · unranked

1 citations

Rebecca S. Hesterberg, Stanislav Drápela, Didem Ilter, Devesh Raizada, Felicia Lazure +8 more

Epstein-Barr-Virus-Driven Cardiolipin Synthesis Sustains Metabolic Remodeling During B-cell Lymphomagenesis

Research Square(2024)10.21203/rs.3.rs-4013392/v1

N/A

0DataRank · unranked

1 citations

Larissa Havey, Zhixuan Li, John M. Asara, Rui Guo, Haixi You

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Data from Integrative Genomic Analysis Implicates Gain of PIK3CA at 3q26 and MYC at 8q24 in Chronic Lymphocytic Leukemia

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Cell Reports(2020)10.1016/j.celrep.2020.107701

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Molecular Cell(2020)10.1016/j.molcel.2020.05.001

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Scientific Reports(2020)10.1038/s41598-020-60387-7

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bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.01.08.899492

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