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Long-range allostery mediates the regulation of plasminogen activator inhibitor-1 by cell adhesion factor vitronectin

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.102652Source: DataRank Database

Long-range allostery mediates the regulation of plasminogen activator inhibitor-1 by cell adhesion factor vitronectin is a research paper published in Journal of Biological Chemistry (2022). On theSindex it has a DataRank of 0. It has been cited 10 times.

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Open Access10 citations

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Enrichment:Funding (6 grants)Impact (FWCI 0.59)OA: goldTopics (41)IDs (PubMed, PMC, OpenAlex)Annotations (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (9)

Elisa Marchiori ORCID,Giovanni Spagnolli ORCID,Alberto Boldrini ORCID,Luca Terruzzi ORCID,Daniel A. Lawrence ORCID

Live enrichment

PubMed:36444882 PMC:PMC9731859 OpenAlex:https://openalex.org/W4307902255

National Institutes of Health

Grant: R01-AG074552

National Institutes of Health

Grant: R01-HL055374

NIA NIH HHS

Grant: R01 AG074552

NHLBI NIH HHS

Grant: R01 HL055374

National Institutes of Health

Grant: 1R01AG074552-01

The Role of PAI-1 in Cerebral Microvascular Dysfunction and the Development of Alzheimer’s Disease Neuropathology

National Institutes of Health

Grant: 7R01HL055374-10

The Biology of Neuroserpin

FWCI

0.59

Citation Percentile

0.6%

Citation Trend

2022

2023

2024

2025

2026

goldLicense: cc-by-nc-nd

journalhttps://doi.org/10.1016/j.jbc.2022.102652

publisherhttps://doi.org/10.1016/j.jbc.2022.102652

publisherhttps://api.elsevier.com/content/article/PII:S002192582201095X?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S002192582201095X?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/36444882

Fields of Study

Protease and Inhibitor MechanismsBiochemical and Structural CharacterizationBlood properties and coagulation0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

Models, MolecularProtein ConformationSolventsCell Adhesion MoleculesPlasminogen Activator Inhibitor 1Vitronectin

Keywords

VitronectinSerpinAllosteric regulationBiophysicsPlasminogen activator inhibitor-1Molecular dynamicsChemistryBinding sitePlasminogen activatorProtein structureConformational changeStereochemistryCrystallographyBiochemistryBiologyIntegrinCellGeneticsEnzymeProtease InhibitionPlasminogen RegulationModels, MolecularProtein ConformationPlasminogen Activator Inhibitor 1Solventsallosteric regulation; molecular dynamics; plasminogen regulation; protease inhibition; serpin;allosteric regulation; molecular dynamics; plasminogen regulation; protease inhibition; serpinCell Adhesion MoleculesResearch Article