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A cell-based bioluminescence reporter assay of human Sonic Hedgehog protein autoprocessing to identify inhibitors and activators

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.102705Source: DataRank Database

A cell-based bioluminescence reporter assay of human Sonic Hedgehog protein autoprocessing to identify inhibitors and activators is a research paper published in Journal of Biological Chemistry (2022). On theSindex it has a DataRank of 0. It has been cited 3 times.

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Open Access3 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (10 grants)Impact (FWCI 0.16)OA: goldTopics (45)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (9)

Patricia Dranchak ORCID,John L. Pezzullo,Rebecca Mancusi ORCID,Alexandra Maria Psaras ORCID,Ganesha Rai ORCID

Live enrichment

PubMed:36400200 PMC:PMC9772569 OpenAlex:https://openalex.org/W4309339019

National Institute of General Medical Sciences

Grant: R15GM143714

National Institutes of Health

Grant: 1ZIATR000053

National Cancer Institute

Grant: R01 CA206592

Intramural NIH HHS

Grant: ZIA TR000053

NIA NIH HHS

Grant: T32 AG078123

NIAID NIH HHS

Grant: R03 AI163907

National Institutes of Health

Grant: 3R01CA206592-03S1

NCI Diversity Fellowship

National Institutes of Health

Grant: 1ZIATR000053-05

Target-based Assays and Screening Strategies for Chemical Probe and Therapeutic Lead Discovery

National Institutes of Health

Grant: 1R15GM143714-01

Sterol Probes of Hedgehog Protein Processing

National Center for Advancing Translational Sciences

FWCI

0.16

Citation Percentile

0.4%

Citation Trend

2023

2026

goldLicense: cc-by-nc-nd

journalhttp://www.jbc.org/article/S0021925822011486/pdf

publisherhttp://www.jbc.org/article/S0021925822011486/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0021925822011486?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0021925822011486?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.jbc.2022.102705

Fields of Study

Hedgehog Signaling Pathway StudiesDevelopmental Biology and Gene RegulationCongenital Ear and Nasal Anomalies0301 basic medicine0303 health sciences03 medical and health sciencesHumansCholesterolHedgehog ProteinsLigandsOncogene ProteinsSterols

MeSH Terms

CholesterolHumansLigandsSterolsOncogene ProteinsHedgehog Proteins

Keywords

MorphogenExtracellularBiochemistryChemistryCell biologyEffectorReporter geneBiologySmoothenedHedgehogSignal transductionGene expressionCholesterolLuciferaseActivatorScreenSonic hedgehogAutoprocessingChemical Rescue1536-WellSmall Molecule DiscoveryOncogene ProteinsSterolsMethods and ResourcesHumansHedgehog ProteinsLigands

Sustainable Development Goals

SDG 3: 3. Good health