Ganesha Rai

Also affiliated with National Human Genome Research Institute, National Center for Advancing Translational Sciences, National Institute of General Medical Sciences

MedicineBiochemistry, Genetics and Molecular BiologyComputer Science

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 4%percentile

0.898Author DataRank

Indexed papers

3in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 3 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Small molecule antiviral compound collection (SMACC): A comprehensive, highly curated database to support the discovery of broad-spectrum antiviral drug molecules

Antiviral Research(2023)10.1016/j.antiviral.2023.105620

Top 35%

0.564DataRank

Top 35%14 citations

Cleber C. Melo‐Filho, Daniel Korn, Richard T. Eastman, Ganesha Rai, Anton Simeonov +4 more

Papers

Driven by 48 papers — median percentile 48. Top paper: “Pyrazole-Based Lactate Dehydrogenase Inhibitors with Optimized Cell Activity and Pharmacokinetic Properties”.

Pyrazole-Based Lactate Dehydrogenase Inhibitors with Optimized Cell Activity and Pharmacokinetic Properties

Journal of Medicinal Chemistry(2020)10.1021/acs.jmedchem.0c00916

N/A

1.7DataRank · unranked

63 citations

Daniel J. Urban, Bryan T. Mott, Xin Hu, Shyh‐Ming Yang, Gloria A. Benavides +40 more

Small molecule antiviral compound collection (SMACC): A comprehensive, highly curated database to support the discovery of broad-spectrum antiviral drug molecules

Antiviral Research(2023)10.1016/j.antiviral.2023.105620

Top 35%

0.564DataRank

Top 35%14 citations

Cleber C. Melo‐Filho, Daniel Korn, Richard T. Eastman, Ganesha Rai, Anton Simeonov +4 more

Identification of a G-Protein-Independent Activator of GIRK Channels

Cell Reports(2020)10.1016/j.celrep.2020.107770

N/A

0.553DataRank · unranked

39 citations

Peter M.U. Ung, Gergely Zahoránszky-Köhalmi, Alexey Zakharov, Natalia J. Martinez, Anton Simeonov +6 more

A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome

Cell Reports(2021)10.1016/j.celrep.2021.109040

N/A

0.515DataRank · unranked

30 citations

Kathleen A. Trychta, Shyh‐Ming Yang, Susanne Bäck, Adam Yasgar, Emily S. Wires +21 more

Lies and Liabilities: Computational Assessment of High-Throughput Screening Hits to Identify Artifact Compounds

Journal of Medicinal Chemistry(2023)10.1021/acs.jmedchem.3c00482

N/A

0.406DataRank · unranked

14 citations

Adam Yasgar, James Wellnitz, Ganesha Rai, Marielle Rath, Rodolpho C. Braga +6 more

ZBTB7A is a modulator of KDM5-driven transcriptional networks in basal breast cancer

Cell Reports(2024)10.1016/j.celrep.2024.114991

N/A

0.362DataRank · unranked

9 citations

Marco Seehawer, Zheqi Li, Andriana Patmanidis, Triet M. Bui, Pierre Foidart +19 more

Small Molecule Antiviral Compound Collection (SMACC): a database to support the discovery of broad-spectrum antiviral drug molecules

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.07.09.499397

Top 52%

0.333DataRank

Top 52%5 citations

Cleber C. Melo‐Filho, Daniel Korn, Richard T. Eastman, Ganesha Rai, Anton Simeonov +4 more

A Comprehensive Phenotypic Screening Strategy to Identify Modulators of Cargo Translocation by the Bacterial Type IVB Secretion System

mBio(2022)10.1128/mbio.00240-22

N/A

0.330DataRank · unranked

8 citations

Dorjbal Dorjsuren, Stephanie S. Lehman, C. L. Larson, Steven A. Titus, Hongmao Sun +6 more

Active- and Allosteric-Site Cyclic Peptide Inhibitors of Secreted M. tuberculosis Chorismate Mutase

ACS Infectious Diseases(2025)10.1021/acsinfecdis.4c00798

N/A

0.208DataRank · unranked

3 citations

Patricia Dranchak, Mahesh Aitha, Lijun Liu, Emma K. Carlson, Isabella E. Jacobsen +9 more

A selective small-molecule agonist of G protein-gated inwardly-rectifying potassium channels reduces epileptiform activity in mouse models of tumor-associated and provoked seizures

Neuropharmacology(2024)10.1016/j.neuropharm.2024.110259

N/A

0.208DataRank · unranked

3 citations

Xiaoping Wu, Brianna Pereira, Brian Gill, Edward M. Merricks, Andrew J. Michalak +9 more

Optimization of ether and aniline based inhibitors of lactate dehydrogenase

Bioorganic & Medicinal Chemistry Letters(2021)10.1016/j.bmcl.2021.127974

N/A

0DataRank · unranked

5 citations

Kwangho Kim, Somnath Jana, Ian M. Romaine, Ganesha Rai, Bryan T. Mott +18 more

Allosteric Binders of ACE2 Are Promising Anti-SARS-CoV-2 Agents

ACS Pharmacology & Translational Science(2022)10.1021/acsptsci.2c00049

N/A

0DataRank · unranked

23 citations

Sankalp Jain, Cleber C. Melo‐Filho, Zoe L. Sessions, Tesia Bobrowski, Jun Choe +10 more

Revealing β-TrCP activity dynamics in live cells with a genetically encoded biosensor

Nature Communications(2022)10.1038/s41467-022-33762-3

N/A

0DataRank · unranked

16 citations

Stephen C. Kales, James A. Cornwell, Marwa M. Afifi, Ganesha Rai, Alexey Zakharov +3 more

XBP1 variant 1 promotes mitosis of cancer cells involving upregulation of the polyglutamylase TTLL6

Human Molecular Genetics(2022)10.1093/hmg/ddac010

N/A

0DataRank · unranked

8 citations

Wenjing Yan, Jingjing Ruan, Mike Fang, Changjun Yu, Shaojun Du +5 more

A Novel 2-Carbon-Linked Dimeric Artemisinin With Potent Antileukemic Activity and Favorable Pharmacology

Frontiers in Oncology(2022)10.3389/fonc.2021.790037

N/A

0DataRank · unranked

6 citations

Blake S. Moses, Bryan T. Mott, Ganesha Rai, Nicole M. Anders, Michelle A. Rudek +2 more

Application of temperature-responsive HIS-tag fluorophores to differential scanning fluorimetry screening of small molecule libraries

Frontiers in Pharmacology(2022)10.3389/fphar.2022.1040039

N/A

0DataRank · unranked

4 citations

Bolormaa Baljinnyam, Zina Itkin, Sankalp Jain, Ganesha Rai, Alexey Zakharov +3 more

A cell-based bioluminescence reporter assay of human Sonic Hedgehog protein autoprocessing to identify inhibitors and activators

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.102705

N/A

0DataRank · unranked

3 citations

Patricia Dranchak, John L. Pezzullo, Rebecca Mancusi, Alexandra Maria Psaras, Ganesha Rai +4 more

Bioluminescence-based reporters for characterizing inhibitors and activators of human Sonic Hedgehog protein autoprocessing in live cells at high throughput

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.06.27.497760

N/A

0DataRank · unranked

0 citations

Patricia Dranchak, John L. Pezzullo, Rebecca Mancusi, Alexandra Maria Psaras, Ganesha Rai +4 more

Methotrexate-based PROTACs as DHFR-specific chemical probes

Cell chemical biology(2023)10.1016/j.chembiol.2023.09.014

N/A

0DataRank · unranked

20 citations

Patricia Dranchak, Jayme L. Dahlin, Laurence Lamy, Wenqing Li, Erin Oliphant +12 more

Discovering selective antiferroptotic inhibitors of the 15LOX/PEBP1 complex noninterfering with biosynthesis of lipid mediators

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2218896120

N/A

0DataRank · unranked

27 citations

Karolina Mikulska‐Ruminska, Yulia Y. Tyurina, Diane K. Luci, Adam Yasgar, Svetlana N. Samovich +23 more

Auranofin targets UBA1 and enhances UBA1 activity by facilitating ubiquitin trans-thioesterification to E2 ubiquitin-conjugating enzymes

Nature Communications(2023)10.1038/s41467-023-40537-x

N/A

0DataRank · unranked

25 citations

Yongwang Zhong, Xin Hu, Tuan Xu, Ying‐Hua Zhang, Stephen C. Kales +13 more

Development of an improved and specific inhibitor of NADPH oxidase 2 to treat traumatic brain injury

Redox Biology(2023)10.1016/j.redox.2023.102611

N/A

0DataRank · unranked

24 citations

Ganesha Rai, A. V. Kozyr, Nathaniel De Jonge, Emily F. Gliniewicz, Lars J. Berg +16 more

ALDH1A1 promotes PARP inhibitor resistance by enhancing retinoic acid receptor-mediated DNA polymerase θ expression

npj Precision Oncology(2023)10.1038/s41698-023-00411-x

N/A

0DataRank · unranked

18 citations

Ananya Banerjee, Na Li, Yajing Yang, Shurui Cai, Xuetao Bai +11 more

Target Class Profiling of Small-Molecule Methyltransferases

ACS Chemical Biology(2023)10.1021/acschembio.3c00124

N/A

0DataRank · unranked

6 citations

Nate Hoxie, Min Shen, Hui Guo, Ig-Jun Cho, Ipsita Chakraborty +6 more

Structural Optimization and Anticancer Activity of Polo-like Kinase 1 (Plk1) Polo-Box Domain (PBD) Inhibitors and Their Prodrugs

ACS Pharmacology & Translational Science(2023)10.1021/acsptsci.2c00250

N/A

0DataRank · unranked

5 citations

Hobin Lee, Paola Oliva, Klára Kirsch, Bo-Ra Kim, Jong Il Ahn +11 more

RALDH1 Inhibition Shows Immunotherapeutic Efficacy in Hepatocellular Carcinoma

Cancer Immunology Research(2023)10.1158/2326-6066.cir-22-1023

N/A

0DataRank · unranked

4 citations

Shuwen Cao, Shyh‐Ming Yang, Ganesha Rai, Natalia J. Martinez, Adam Yasgar +11 more

Supplemental Methods from Targeting Glycolysis through Inhibition of Lactate Dehydrogenase Impairs Tumor Growth in Preclinical Models of Ewing Sarcoma

(2023)10.1158/0008-5472.22422704

N/A

0DataRank · unranked

0 citations

Anna E. Gibson, Sameer H. Issaq, Nobu Oshima, Joshua T. Baumgart, Leah D. Edessa +23 more

Supplemental Methods from Targeting Glycolysis through Inhibition of Lactate Dehydrogenase Impairs Tumor Growth in Preclinical Models of Ewing Sarcoma

Figshare(2023)10.1158/0008-5472.22422704.v1

N/A

0DataRank · unranked

0 citations

Anna E. Gibson, Sameer H. Issaq, Nobu Oshima, Joshua T. Baumgart, Leah D. Edessa +23 more

ART714 is a best-in-class antileukemic 2-carbon-linked dimeric artemisinin derivative

Cancer Chemotherapy and Pharmacology(2023)10.1007/s00280-023-04539-2

N/A

0DataRank · unranked

0 citations

Blake S. Moses, Rena G. Lapidus, Bryan T. Mott, Ganesha Rai, Nicole M. Anders +4 more

Small-Molecule Disruptors of the Interaction between Calcium- and Integrin-Binding Protein 1 and Integrin αIIbβ3 as Novel Antiplatelet Agents

ACS Pharmacology & Translational Science(2024)10.1021/acsptsci.4c00026

N/A

0DataRank · unranked

4 citations

Adam Yasgar, Voddarahally N. Manjuprasanna, Meghna U. Naik, Bolormaa Baljinnyam, Alexey Zakharov +6 more

Cell-Based Covalent-Capture Deubiquitinase Assay for Inhibitor Discovery

ACS Pharmacology & Translational Science(2024)10.1021/acsptsci.4c00331

N/A

0DataRank · unranked

2 citations

Jenna Miller, Sankalp Jain, Alexey Zakharov, Ganesha Rai, Anton Simeonov +3 more

AI-driven drug discovery: identification and optimization of ALDH3A1 selective inhibitors with nanomolar activity

ChemRxiv(2024)10.26434/chemrxiv-2024-5zxxm

N/A

0DataRank · unranked

2 citations

Adam Yasgar, Anu Dalal, Marissa A. Davies, Aleksandra Nilova, Natalia J. Martinez +4 more

Integrated Approach of Machine Learning and High-Throughput Screening to Identify Chemical Probe Candidates Targeting Aldehyde Dehydrogenases

ACS Pharmacology & Translational Science(2025)10.1021/acsptsci.5c00395

N/A

0DataRank · unranked

4 citations

Sankalp Jain, Marissa A. Davies, Carina Danchik, Taylor Niehoff, Ran Jing +6 more

Discovery and Optimization of LATS1 and LATS2 Kinase Inhibitors for Use in Regenerative Medicine

Journal of Medicinal Chemistry(2025)10.1021/acs.jmedchem.5c01027

N/A

0DataRank · unranked

0 citations

Damien Duveau, Michele Ceribelli, Frances Anne Tosto, Dara N. Love, Bridget S. Scherer +9 more

Cyclic peptides as ligands for competition binding assays

Methods in enzymology on CD-ROM/Methods in enzymology(2025)10.1016/bs.mie.2025.08.021

N/A

0DataRank · unranked

0 citations

Patricia Dranchak, A.K. Davis, Ganesha Rai, James Inglese, Renier H. P. van Neer

Small molecule antiviral compound collection (SMACC): A comprehensive, highly curated database to support the discovery of broad-spectrum antiviral drug molecules

UNC Libraries(2025)10.17615/pwav-1m04

Top 100%

0DataRank

Top 100%0 citations

Ganesha Rai, Eugene Muratov, Alexander Tropsha, Daniel Korn, Anton Simeonov +4 more

Lies and Liabilities: Computational Assessment of High-Throughput Screening Hits to Identify Artifact Compounds

UNC Libraries(2025)10.17615/srnb-f444

N/A

0DataRank · unranked

0 citations

Ganesha Rai, Marielle Rath, Anton Simeonov, Eugene Muratov, Alexey Zakharov +6 more

Dynamic Imaging of LDH Inhibition in Tumors Reveals Rapid In Vivo Metabolic Rewiring and Vulnerability to Combination Therapy

Cell Reports(2020)10.1016/j.celrep.2020.01.039

N/A

0DataRank · unranked

125 citations

Ryo Ishida, Shun Kishimoto, Kristin Beebe, Jeffrey Brender, Kazutoshi Yamamoto +36 more

Mass spectrometry-guided discovery of novel GCPII inhibitor scaffolds

Frontiers in Pharmacology(2025)10.3389/fphar.2025.1646207

N/A

0DataRank · unranked

0 citations

Ajit G. Thomas, John Janiszewski, Nate Hoxie, Chae Bin Lee, Ying Wu +13 more

A 12‐lipoxygenase‐Gpr31 signaling axis is required for pancreatic organogenesis in the zebrafish

The FASEB Journal(2020)10.1096/fj.201902308rr

N/A

0DataRank · unranked

20 citations

Abhishek Kulkarni, Niharika Samala, Cody A. Sorrell, Kimberley El, Isra Haider +7 more

Identification of a New Heterocyclic Scaffold for Inhibitors of the Polo-Box Domain of Polo-like Kinase 1

Journal of Medicinal Chemistry(2020)10.1021/acs.jmedchem.0c01669

N/A

0DataRank · unranked

21 citations

Jung‐Eun Park, Kiran S. Toti, Yangliu Xia, Kristopher W. Krausz, Ganesha Rai +5 more

The AKT modulator A-443654 reduces α-synuclein expression and normalizes ER stress and autophagy

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.101191

N/A

0DataRank · unranked

40 citations

Warunee Dansithong, Stephen C. Kales, Sharan Paul, Gentrie Maag, Erika Aoyama +12 more

Kinetic and structural investigations of novel inhibitors of human epithelial 15-lipoxygenase-2

Bioorganic & Medicinal Chemistry(2021)10.1016/j.bmc.2021.116349

N/A

0DataRank · unranked

28 citations

Nathaniel C. Gilbert, Amanda Ohler, Michelle Armstrong, Steve Perry, Chakrapani Kalyanaraman +14 more

NOX2 inhibitor GSK2795039 metabolite identification towards drug optimization

Journal of Pharmaceutical and Biomedical Analysis(2021)10.1016/j.jpba.2021.114102

N/A

0DataRank · unranked

23 citations

Pranav Shah, Ganesha Rai, Xin Xu, Elias Carvalho Padilha

Hybrid In Silico Approach Reveals Novel Inhibitors of Multiple SARS-CoV-2 Variants

ACS Pharmacology & Translational Science(2021)10.1021/acsptsci.1c00176

N/A

0DataRank · unranked

16 citations

Daniel C. Talley, Bolormaa Baljinnyam, Jun Choe, Quinlin Hanson, Wei Zhu +10 more

Small Molecule Inhibitors of Activation-Induced Deaminase Decrease Class Switch Recombination in B Cells

ACS Pharmacology & Translational Science(2021)10.1021/acsptsci.1c00064

N/A

0DataRank · unranked

12 citations

Adam Yasgar, Robert W. Maul, Amanda E. Rieffer, Daniel Crawford, Daniel J. Salamango +10 more

Structure–activity relationship of ipglycermide binding to phosphoglycerate mutases

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.100628

N/A

0DataRank · unranked

9 citations

Patricia Dranchak, Mahesh Aitha, Bryan Queme, Christopher D. Collmus, M.M. Kashipathy +10 more

Genome-Edited Coincidence and PMP22-HiBiT Fusion Reporter Cell Lines Enable an Artifact-Suppressive Quantitative High-Throughput Screening Strategy for PMP22 Gene-Dosage Disorder Drug Discovery

ACS Pharmacology & Translational Science(2021)10.1021/acsptsci.1c00110

N/A

0DataRank · unranked

9 citations

John Braisted, Patricia Dranchak, John J. Moran, Hunter G. Larson, Bryan Queme +7 more

Ganesha Rai

Indexed papers

Top data-sharing exemplar

Papers