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Macromolecular crowding potently stimulates DNA supercoiling activity of Mycobacterium tuberculosis DNA gyrase

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.105439Source: DataRank Database

Macromolecular crowding potently stimulates DNA supercoiling activity of Mycobacterium tuberculosis DNA gyrase is a research paper published in Journal of Biological Chemistry (2023). On theSindex it has a DataRank of 0. It has been cited 8 times.

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Open Access8 citations

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Enrichment:Funding (6 grants)Impact (FWCI 0.62)OA: goldTopics (44)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (3)

Prem P. Chapagain ORCID,Fenfei Leng ORCID,Zifang Deng

Live enrichment

PubMed:37944619 PMC:PMC10731242 OpenAlex:https://openalex.org/W4388451797

National Institutes of Health

Grant: 1R21AI125973

National Institutes of Health

Grant: 1R21AI178134

NIAID NIH HHS

Grant: R21 AI178134

NIAID NIH HHS

Grant: R21 AI125973

National Institutes of Health

Grant: 1R21AI125973-01A1

Targeting transcription-coupled DNA supercoiling for discovering antibiotics against bacterial DNA gyrase

National Institutes of Health

Grant: 5R21AI178134-02

Novel gyrase inhibitors targeting Mycobacterium tuberculosis

FWCI

0.62

Citation Percentile

0.6%

Citation Trend

2024

2025

2026

goldLicense: cc-by

journalhttps://doi.org/10.1016/j.jbc.2023.105439

publisherhttps://doi.org/10.1016/j.jbc.2023.105439

publisherhttps://api.elsevier.com/content/article/PII:S0021925823024675?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0021925823024675?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/37944619

Fields of Study

Antibiotic Resistance in BacteriaCancer therapeutics and mechanismsDNA and Nucleic Acid Chemistry0301 basic medicine03 medical and health sciencesDNA GyraseMycobacterium tuberculosisBetaineKineticsAdenosine TriphosphateDNADNA, Superhelical

MeSH Terms

Adenosine TriphosphateBetaineDNADNA, SuperhelicalKineticsMycobacterium tuberculosisDNA Gyrase

Keywords

DNA gyraseDNA supercoilDNACircular bacterial chromosomeChemistryBiochemistryBiophysicsMolecular biologyBiologyEscherichia coliDNA polymeraseDNA replicationPEGMolecular dynamics simulationPVAMacromolecular crowdingExcluded VolumeWater ActivityMtb Dna GyraseBetaineKineticsAdenosine TriphosphateDNA, SuperhelicalMycobacterium tuberculosisResearch Article

Sustainable Development Goals

SDG 0: Clean water and sanitation

Macromolecular crowding potently stimulates DNA supercoiling activity of Mycobacterium tuberculosis DNA gyrase

FAIR Checklist

Authors (3)

Funding (6 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)