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C-spine mutations of protein kinase C and Akt as a novel generalizable approach to create stable pseudokinases

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.110921Source: DataRank Database

C-spine mutations of protein kinase C and Akt as a novel generalizable approach to create stable pseudokinases is a research paper published in Journal of Biological Chemistry (2025). On theSindex it has a DataRank of 0. It has been cited 2 times.

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Open Access2 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (8 grants)Impact (FWCI 0.77)OA: goldTopics (49)IDs (PubMed, PMC, OpenAlex)Annotations (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (7)

Tiffany Kao ORCID,Jian Wu ORCID,Nileeka Balasuriya,Corina E. Antal ORCID,Susan S. Taylor ORCID

Live enrichment

PubMed:41207627 PMC:PMC12721161 OpenAlex:https://openalex.org/W4416008059

University of California, San Diego

Grant: T32 GM007752

National Institutes of Health

Grant: R35 GM122523

National Institutes of Health

Grant: R35 GM130389

National Institutes of Health

Grant: R03 TR002914

National Institutes of Health

Grant: F31 HL168916

Natural Sciences and Engineering Research Council of Canada

Grant: PDF 587869 - 2024

Natural Sciences and Engineering Research Council of Canada

Grant: unidentified

unidentified

National Heart, Lung, and Blood Institute

FWCI

0.77

Citation Percentile

0.7%

Citation Trend

2026

goldLicense: cc-by

journalhttps://doi.org/10.1016/j.jbc.2025.110921

publisherhttps://doi.org/10.1016/j.jbc.2025.110921

publisherhttps://api.elsevier.com/content/article/PII:S0021925825027735?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0021925825027735?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/41207627

Fields of Study

Protein Kinase Regulation and GTPase SignalingPI3K/AKT/mTOR signaling in cancerMicrotubule and mitosis dynamics0301 basic medicine03 medical and health sciencesProto-Oncogene Proteins c-aktHumansProtein Kinase CPhosphorylationMutationAdenosine TriphosphateIsoenzymesCatalytic DomainHEK293 CellsAnimalsModels, Molecular

MeSH Terms

Adenosine TriphosphateAnimalsHumansIsoenzymesModels, MolecularMutationPhosphorylationProtein Kinase CCatalytic DomainProto-Oncogene Proteins c-aktHEK293 Cells

Keywords

AutophosphorylationMutantKinaseProtein kinase APhosphorylationProtein kinase CAdenosine kinaseMutationProtein kinase BAKTPseudokinaseC-spineKinase-deadModels, MolecularIsoenzymesAdenosine TriphosphateHEK293 CellsCatalytic DomainHumansAnimalsProto-Oncogene Proteins c-aktResearch Article

C-spine mutations of protein kinase C and Akt as a novel generalizable approach to create stable pseudokinases

FAIR Checklist

Authors (7)

Funding (8 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)