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A revised model of nuclear actin import: Importin 9 competes with cofilin, profilin, and RanGTP for actin binding

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.111123Source: DataRank Database

A revised model of nuclear actin import: Importin 9 competes with cofilin, profilin, and RanGTP for actin binding is a research paper published in Journal of Biological Chemistry (2025). On theSindex it has a DataRank of 0. It has been cited 1 time.

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Open Access1 citations

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Enrichment:Funding (5 grants)Impact (FWCI 0.39)OA: goldTopics (42)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (5)

Prithi A Srinivasan,S. Christensen ORCID,Cristian Suarez ORCID,Alexander J. Ruthenburg ORCID,Amanda J. Keplinger ORCID

Live enrichment

PubMed:41478570 PMC:PMC12860355 OpenAlex:https://openalex.org/W7117656753

National Institute of General Medical Sciences

Grant: R35-GM145373

NIGMS NIH HHS

Grant: R35 GM145373

Cancer Research Foundation

National Science Foundation

National Institutes of Health

FWCI

0.39

Citation Percentile

0.7%

Citation Trend

2026

goldLicense: cc-by

journalhttps://www.jbc.org/article/S0021-9258(25)02975-8/pdf

publisherhttps://www.jbc.org/article/S0021-9258(25)02975-8/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0021925825029758?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0021925825029758?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.jbc.2025.111123

Fields of Study

Nuclear Structure and FunctionCellular Mechanics and InteractionsCardiomyopathy and Myosin StudiesActinsProfilinsCell NucleusActin Depolymerizing FactorsHumansActive Transport, Cell Nucleusran GTP-Binding Proteinbeta KaryopherinsProtein BindingAnimalsKaryopherinsModels, Biological

MeSH Terms

ActinsAnimalsCell NucleusHumansModels, BiologicalProtein Bindingran GTP-Binding ProteinActive Transport, Cell NucleusKaryopherinsbeta KaryopherinsProfilinsActin Depolymerizing Factors

Keywords

CofilinRanActin remodelingActin-binding proteinActinNuclear transportMDia1ProfilinKineticsSurface plasmon resonanceProtein importthermodynamicsnuclear translocationProtein–protein InteractionG-actin

Sustainable Development Goals

SDG 0: Partnerships for the goals

A revised model of nuclear actin import: Importin 9 competes with cofilin, profilin, and RanGTP for actin binding

FAIR Checklist

Authors (5)

Funding (5 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)