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PTPN2 Is a Critical Regulator of Ileal Paneth Cell Viability and Function in Mice

Cellular and Molecular Gastroenterology and Hepatology(2023)10.1016/j.jcmgh.2023.03.009Source: DataRank Database

PTPN2 Is a Critical Regulator of Ileal Paneth Cell Viability and Function in Mice is a research paper published in Cellular and Molecular Gastroenterology and Hepatology (2023). On theSindex it has a DataRank of 0.385. It has been cited 12 times.

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0.385DataRank · unranked

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Open Access12 citations

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Enrichment:Funding (13 grants)OA: goldTopics (67)IDs (PubMed)

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Accessible (1/2)

Open Access

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Reusable (0/3)

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DataRank Breakdown

Base Score 100%Citation Network 0%

Base Score Contribution

0.385

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Citation Network Contribution

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Authors (16)

Marianne R. Spalinger ORCID,Rocio Alvarez ORCID,Anica Sayoc-Becerra ORCID,Golshid Sanati ORCID,Salomon Manz ORCID

Live enrichment

PubMed:37030630

National Institutes of Health

Grant: 1R01AI153314-01

Tyrosine Phosphatase Regulation of Mucosal Macrophage-Epithelial Cell Cross-talk

National Institutes of Health

Grant: 1R01DK130373

National Institutes of Health

Grant: 2R01-DK091281

National Institutes of Health

Grant: P30 DK120515

National Institutes of Health

Grant: R01AI165490

National Institutes of Health

Grant: R21AI152017

National Institutes of Health

Grant: 5R01DK091281-07

A novel role for PTPN2 in intestinal epithelial barrier regulation

National Institutes of Health

Grant: 5P30DK120515-04

San Diego Digestive Diseases Research Center

National Institutes of Health

Grant: 1R01DK130373-01

Mechanistic Characterization of the IBD Risk Gene, PTPN2, as a Novel Susceptibility Marker for Increased SARS-CoV-2 Infection

National Institutes of Health

Grant: 1R21AI152017-01A1

Inflammatory Bowel Disease Susceptibility Gene Regulation of Anemia

NIDDK NIH HHS

Grant: R01 DK130373

NIDDK NIH HHS

Grant: R01 DK091281

NIAID NIH HHS

Grant: R01 AI153314

goldLicense: CC BY NC ND

publisherhttps://doi.org/10.1016/j.jcmgh.2023.03.009

publisherhttps://api.elsevier.com/content/article/PII:S2352345X23000498?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S2352345X23000498?httpAccept=text/plain

repositoryhttps://escholarship.org/content/qt4x6590cz/qt4x6590cz.pdf?t=rxtid5

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10213106/pdf/main.pdf

Fields of Study

0301 basic medicine03 medical and health sciencesMiceAnimalsPaneth CellsProtein Tyrosine Phosphatase, Non-Receptor Type 2Cell SurvivalInflammatory Bowel DiseasesIleumMice, Knockout

MeSH Terms

MiceAnimalsPaneth CellsProtein Tyrosine Phosphatase, Non-Receptor Type 2Cell SurvivalInflammatory Bowel DiseasesIleumMice, Knockout

Keywords

Medical BiotechnologyCell Survival (mesh)Clinical sciencesRC799-869Ileum (mesh)Mice3206 Medical Biotechnology (for-2020)2.1 Biological and endogenous factorsAnimals (mesh)32 Biomedical and Clinical Sciences (for-2020)3101 Biochemistry and cell biology (for-2020)Non-Receptor Type 2Original ResearchMice, KnockoutProtein Tyrosine Phosphatase, Non-Receptor Type 2Mice (mesh)Inflammatory Bowel Diseases (mesh)Biological SciencesDiseases of the digestive system. GastroenterologyKnockout (mesh)TCPTPAntimicrobial PeptidesDigestive Diseases (rcdc)Paneth CellsCell Survival1.1 Normal biological development and functioningKnockoutLysozyme610Non-Receptor Type 2 (mesh)Autoimmune DiseaseIleumInflammatory Bowel Disease (rcdc)Animals1.1 Normal biological development and functioning (hrcs-rac)Autoimmune Disease (rcdc)31 Biological Sciences (for-2020)Biomedical and Clinical SciencesInflammatory Bowel Disease5002.1 Biological and endogenous factors (hrcs-rac)3202 Clinical sciences (for-2020)Inflammatory Bowel DiseasesBiochemistry and cell biologyPaneth Cells (mesh)Intestinal Epithelial CellsProtein Tyrosine PhosphataseMicrobiomeDigestive Diseases