Marianne R. Spalinger

Also affiliated with University Hospital Zurich

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 15 papers. Top paper: “PTPN2 Regulates Interactions Between Macrophages and Intestinal Epithelial Cells to Promote Intestinal Barrier Function”.

PTPN2 Regulates Interactions Between Macrophages and Intestinal Epithelial Cells to Promote Intestinal Barrier Function

Gastroenterology(2020)10.1053/j.gastro.2020.07.004

N/A

0.750DataRank · unranked

147 citations

Anica Sayoc-Becerra, Alina N. Santos, Ali Shawki, Vinicius Canale, Moorthy Krishnan +7 more

Autoimmune susceptibility gene PTPN2 is required for clearance of adherent-invasive Escherichia coli by integrating bacterial uptake and lysosomal defence

Gut(2021)10.1136/gutjnl-2020-323636

N/A

0.489DataRank · unranked

25 citations

Ali Shawki, Pritha Chatterjee, Vinicius Canale, Alina N. Santos, Anica Sayoc-Becerra +5 more

SKAP2—A Molecule at the Crossroads for Integrin Signalling and Immune Cell Migration and Function

Biomedicines(2023)10.3390/biomedicines11102788

N/A

0.457DataRank · unranked

20 citations

Marianne R. Spalinger, Marijn Wilmink

Loss of protein tyrosine phosphatase non-receptor type 2 reduces IL-4-driven alternative macrophage activation

Mucosal Immunology(2021)10.1038/s41385-021-00441-3

N/A

0.425DataRank · unranked

16 citations

Meli’sa S. Crawford, Sarah D. Bobardt, Jiang Li, Anica Sayoc-Becerra, Alina N. Santos +5 more

PTPN2 Is a Critical Regulator of Ileal Paneth Cell Viability and Function in Mice

Cellular and Molecular Gastroenterology and Hepatology(2023)10.1016/j.jcmgh.2023.03.009

N/A

0.385DataRank · unranked

12 citations

Marianne R. Spalinger, Rocio Alvarez, Anica Sayoc-Becerra, Golshid Sanati, Salomon Manz +11 more

PTPN2 Regulates Iron Handling Protein Expression in Inflammatory Bowel Disease Patients and Prevents Iron Deficiency in Mice

International Journal of Molecular Sciences(2025)10.3390/ijms26073356

N/A

0.269DataRank · unranked

5 citations

Ali Shawki, Alina N. Santos, Vinicius Canale, Salomon Manz, Meli’sa S. Crawford +5 more

Intestinal epithelial PTPN2 limits pathobiont colonization by immune-directed antimicrobial responses

Gut Microbes(2025)10.1080/19490976.2025.2559029

N/A

0.104DataRank · unranked

1 citations

Marianne R. Spalinger, Charly Acevedo, Alina N. Santos, Casey M. Gries, Salomon Manz +9 more

The JAK Inhibitor Tofacitinib Rescues Intestinal Barrier Defects Caused by Disrupted Epithelial-macrophage Interactions

Journal of Crohn s and Colitis(2020)10.1093/ecco-jcc/jjaa182

N/A

0DataRank · unranked

79 citations

Anica Sayoc-Becerra, Christ Ordookhanian, Vinicius Canale, Alina N. Santos, Stephanie King +5 more

Identification of a Novel Susceptibility Marker for SARS-CoV-2 Infection in Human Subjects and Risk Mitigation with a Clinically Approved JAK Inhibitor in Human/Mouse Cells

Anthropos eBooks(2020)10.1101/2020.12.09.416586

N/A

0DataRank · unranked

10 citations

Rong Hai, Li Jiang, Alina N. Santos, Tara M. Nordgren, Michel L. Tremblay +7 more

Intestinal Epithelial PTPN2 Limits Pathobiont Colonization by Immune-Directed Antimicrobial Responses

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.09.24.614848

N/A

0DataRank · unranked

0 citations

Marianne R. Spalinger, Charly Acevedo, Casey M. Gries, Salomon Manz, Vinicius Canale +9 more

Gut microbiota-dependent increase in phenylacetic acid induces endothelial cell senescence during aging

Nature Aging(2025)10.1038/s43587-025-00864-8

N/A

0DataRank · unranked

46 citations

Benoı̂t Pugin, Florentin Constancias, Khatereh Shabanian, Marianne R. Spalinger, Aurélien Thomas +16 more

Tofacitinib Mitigates the Increased SARS-CoV-2 Infection Susceptibility Caused by an IBD Risk Variant in the PTPN2 Gene

Cellular and Molecular Gastroenterology and Hepatology(2025)10.1016/j.jcmgh.2024.101447

N/A

0DataRank · unranked

3 citations

Golshid Sanati, Pritha Chatterjee, Rong Hai, Li Jiang, Alina N. Santos +9 more

PTPN2 regulates bacterial clearance in a mouse model of enteropathogenic and enterohemorrhagic E. coli infection

JCI Insight(2023)10.1172/jci.insight.156909

N/A

0DataRank · unranked

6 citations

Vinicius Canale, Anica Becerra, Ali Shawki, Meli’sa S. Crawford, Alina N. Santos +5 more

T cell protein tyrosine phosphatase protects intestinal barrier function by restricting epithelial tight junction remodeling

Journal of Clinical Investigation(2021)10.1172/jci138230

N/A

0DataRank · unranked

45 citations

Moorthy Krishnan, Marianne R. Spalinger, Taylaur W. Placone, Rocio Alvarez, Anica Sayoc-Becerra +15 more

Presence of PTPN2 SNP rs1893217 Enhances the Anti-inflammatory Effect of Spermidine

Inflammatory Bowel Diseases(2020)10.1093/ibd/izaa013

N/A

0DataRank · unranked

9 citations

Matthias Butter, Salomon Manz, Nicole Obialo, Katharina Bäbler, Lisa van der Lely +6 more