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Crystal Structures of Ternary Complexes of MEF2 and NKX2–5 Bound to DNA Reveal a Disease Related Protein–Protein Interaction Interface

Journal of Molecular Biology(2020)10.1016/j.jmb.2020.07.004Source: DataRank Database

Crystal Structures of Ternary Complexes of MEF2 and NKX2–5 Bound to DNA Reveal a Disease Related Protein–Protein Interaction Interface is a research paper published in Journal of Molecular Biology (2020). On theSindex it has a DataRank of 0. It has been cited 5 times.

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Enrichment:Funding (8 grants)Impact (FWCI 0.22)OA: greenTopics (43)IDs (PubMed, PMC, OpenAlex)Annotations (2)

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Context only (not used in score)

Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (10)

Jun Zhao ORCID,Jared M. Sagendorf ORCID,Niroop Rajashekar ORCID,Jiang Xu ORCID,Ana Carolina Dantas Machado ORCID

Live enrichment

PubMed:32681840 PMC:PMC8099449 OpenAlex:https://openalex.org/W3042985605

National Institutes of Health

Grant: 5U54DK107981

NHGRI NIH HHS

Grant: R21 HG010528

National Institutes of Health

Grant: R01AI113009

NIDDK NIH HHS

Grant: U54 DK107981

NIGMS NIH HHS

Grant: R35 GM130376

National Institutes of Health

Grant: 5R35GM130376-03

Quantitative Modeling of Transcription Factor-DNA Binding

National Institutes of Health

Grant: 5U54DK107981-04

Mapping the 3D Genome Landscape

National Institutes of Health

Grant: 5R01AI113009-05

Explore FOXP3's role in the 3D organization of the genome

FWCI

0.22

Citation Percentile

0.5%

Citation Trend

2022

2023

2024

2025

greenLicense: Elsevier TDM

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8099449

journalhttps://doi.org/10.1016/j.jmb.2020.07.004

repositoryhttps://pubmed.ncbi.nlm.nih.gov/32681840

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099449

Fields of Study

Genomics and Chromatin DynamicsCongenital heart defects researchRNA Research and Splicing0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

Homeobox Protein Nkx-2.5Amino Acid SequenceBinding SitesDNAHumansProtein BindingCrystallography, X-RayProtein Interaction Domains and MotifsProtein Interaction MapsMolecular Docking SimulationMEF2 Transcription Factors

Keywords

Mef2DNAEnhancerTranscription factorTernary complexBiologyTranscription (linguistics)Cell biologyGeneticsGeneChemistryBiochemistryTranscription regulationcardiogenesisProtein–protein InteractionNkx2–5Binding SitesMEF2 Transcription FactorsCrystallography, X-RayMolecular Docking SimulationHomeobox Protein Nkx-2.5HumansProtein Interaction Domains and MotifsAmino Acid SequenceProtein Interaction MapsProtein Binding

Crystal Structures of Ternary Complexes of MEF2 and NKX2–5 Bound to DNA Reveal a Disease Related Protein–Protein Interaction Interface

FAIR Checklist

Authors (10)

Funding (8 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)