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mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis

Molecular Cell(2021)10.1016/j.molcel.2021.03.009Source: DataRank Database

mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis is a research paper published in Molecular Cell (2021). On theSindex it has a DataRank of 0. It has been cited 179 times.

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Open Access179 citations

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Enrichment:Funding (13 grants)Impact (FWCI 9.11)OA: bronzeTopics (49)IDs (PubMed, PMC, OpenAlex)Annotations (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (9)

Umakant Sahu ORCID,Brendan P. O’Hara,Eunüs S. Ali ORCID,Kathryn A. Helmin ORCID,John M. Asara ORCID

Live enrichment

PubMed:33756106 PMC:PMC8141029 OpenAlex:https://openalex.org/W3138260440

National Cancer Institute

Grant: CA060553

Tuberous Sclerosis Alliance

Grant: SP0057487

LAM Foundation

Grant: LAM0127C01-18

National Institutes of Health

Grant: R01GM135587

National Institutes of Health

Grant: R00CA194192-04

National Institutes of Health

Grant: K08HL128867

National Institutes of Health

Grant: R01HL149883

NCI NIH HHS

Grant: P30 CA060553

NIGMS NIH HHS

Grant: R01 GM143334

NCI NIH HHS

Grant: R00 CA194192

NCI NIH HHS

Grant: P01 CA120964

Philippe Foundation

Northwestern University

FWCI

9.11

Citation Percentile

1.0%

Citation Trend

2021

2022

2023

2024

2025

2026

bronzeLicense: http://www.elsevier.com/open-access/userlicense/1.0/

journalhttp://www.cell.com/article/S1097276521001775/pdf

publisherhttp://www.cell.com/article/S1097276521001775/pdf

publisherhttps://api.elsevier.com/content/article/PII:S1097276521001775?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1097276521001775?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.molcel.2021.03.009

Fields of Study

RNA modifications and cancerCancer-related gene regulationEpigenetics and DNA Methylation

MeSH Terms

RNA Splicing FactorsMechanistic Target of Rapamycin Complex 1AdenosineAnimalsBase SequenceBreast NeoplasmsFemaleHeLa CellsHumansMethionine AdenosyltransferaseMethylationMice, NudeRNA, MessengerS-AdenosylmethionineTranscription, GeneticProtein BiosynthesisSignal TransductionProto-Oncogene Proteins c-mycCell Cycle ProteinsCell ProliferationMiceHEK293 CellsHela Cells

Keywords

mTORC1BiologyProtein biosynthesisCell biologyRNAMessenger RNAMethionine AdenosyltransferaseTranslation (biology)Cell growthMethionineBiochemistrySignal transductionPI3K/AKT/mTOR pathwayGeneAmino acidProtein synthesisS-AdenosylmethionineMtorRna MetabolismMethionine CycleN(6)-methyladenosineMat2aWtap

mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis

FAIR Checklist

Authors (9)

Funding (13 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)