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Functional landscape of SARS-CoV-2 cellular restriction

Molecular Cell(2021)10.1016/j.molcel.2021.04.008Source: DataRank Database

Functional landscape of SARS-CoV-2 cellular restriction is a research paper published in Molecular Cell (2021). On theSindex it has a DataRank of 4.8. It has been cited 228 times, with 100 citing works in its 1-hop citation network.

N/A

4.8DataRank · unranked

Scored on demand from live citation data

Deposits data Open Access228 citations · 100 citing works in its network

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Linked data & code

geo cellosaurus gen doi pdb

Data availability

Repositories this paper deposited data in (declared in PubMed).

GEOGSE156295

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (19 grants)Impact (FWCI 11.71)OA: bronzeTopics (77)Linked Datasets (4)DataCite Reuse (4)IDs (PubMed, PMC, OpenAlex)Annotations (5)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (2/2)

Has DOI
Indexed in repositories

Accessible (1/2)

Open Access

Interoperable (2/2)

DataCite relations
Linked datasets

Reusable (0/3)

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DataRank Breakdown

Base Score 17%Citation Network 83%

Base Score Contribution

0.815

From this paper's citation signal

Citation Network Contribution

4.0

From 100 citing papers with measurable signal

Learn more about DataRank methodology →

Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 100 citers.

Rapid spread of a SARS-CoV-2 Delta variant with a frameshift deletion in ORF7a
medRxiv202111 citations6 referencesContributes 0.414
Clash of the titans: interferons and SARS-CoV-2
Trends in Immunology202118 citations15 referencesContributes 0.196
SARS-CoV-2 Omicron Induces Enhanced Mucosal Interferon Response Compared to other Variants of Concern, Associated with Restricted Replication in Human Lung Tissues
Viruses202223 citations24 referencesContributes 0.132
Differential induction of type I and III interferon genes in the upper respiratory tract of patients with coronavirus disease 2019 (COVID-19)
Virus Research202134 citations28 referencesContributes 0.127
Pre-activated antiviral innate immunity in the upper airways controls early SARS-CoV-2 infection in children
Nature Biotechnology2021395 citations51 referencesContributes 0.117

Authors (34)

Mary K. Lewinski ORCID,Lars Pache ORCID,Charlotte A. Stoneham ORCID,Xin Yin ORCID,Mark E. Becker ORCID

Live enrichment

PubMed:33930332 PMC:PMC8043580 OpenAlex:https://openalex.org/W3156257761

DARPA

Grant: HR0011-19-2-0020

National Institutes of Health

Grant: R37AI081668

National Institute of Allergy and Infectious Diseases

Grant: HHSN272201400008C

NCATS

Grant: UL1 TR002389

JPB Foundation

Grant: 2020-215611 (5384)

NIAID NIH HHS

Grant: F31 AI141111

NCATS NIH HHS

Grant: UL1 TR001422

NIAID NIH HHS

Grant: U19 AI135972

NCI NIH HHS

Grant: P30 CA030199

NCI NIH HHS

Grant: P30 CA060553

NIAID NIH HHS

Grant: R21 AI163912

NIAID NIH HHS

Grant: U19 AI118610

NIGMS NIH HHS

Grant: P41 GM103504

NIAID NIH HHS

Grant: U19 AI168631

NIAID NIH HHS

Grant: U19 AI135990

NCATS

National Institute of Allergy and Infectious Diseases

DARPA

US Department of Defense Military Health System

FWCI

11.71

Citation Percentile

1.0%

Citation Trend

2020

2021

2022

2023

2024

2025

2026

bronzeLicense: http://www.elsevier.com/open-access/userlicense/1.0/

journalhttp://www.cell.com/article/S1097276521003130/pdf

publisherhttp://www.cell.com/article/S1097276521003130/pdf

publisherhttps://api.elsevier.com/content/article/PII:S1097276521003130?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1097276521003130?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.molcel.2021.04.008

Fields of Study

SARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research StudiesLong-Term Effects of COVID-19AnimalsAntigens, CDBinding SitesCell Line, TumorChlorocebus aethiopsEndoplasmic ReticulumGPI-Linked ProteinsGene Expression RegulationGolgi ApparatusHEK293 CellsHost-Pathogen InteractionsHumansImmunity, InnateInterferon Regulatory FactorsInterferon Type IMolecular Docking SimulationProtein BindingProtein Conformation, alpha-HelicalProtein Conformation, beta-StrandProtein Interaction Domains and MotifsSARS-CoV-2Signal TransductionVero CellsViral ProteinsVirus InternalizationVirus ReleaseVirus ReplicationBone Marrow Stromal Antigen 2

MeSH Terms

Protein Conformation, alpha-HelicalProtein Conformation, beta-StrandBone Marrow Stromal Antigen 2SARS-CoV-2AnimalsBinding SitesChlorocebus aethiopsEndoplasmic ReticulumGene Expression RegulationGolgi ApparatusHumansImmunity, InnateInterferon Type IProtein BindingVero CellsViral ProteinsVirus ReplicationSignal TransductionAntigens, CDCell Line, TumorInterferon Regulatory FactorsVirus InternalizationProtein Interaction Domains and MotifsHost-Pathogen InteractionsVirus ReleaseHEK293 CellsGPI-Linked ProteinsMolecular Docking Simulation

Keywords

BiologySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus disease 2019 (COVID-19)2019-20 coronavirus outbreakComputational biologySars virusVirologyEvolutionary biologyDiseaseInfectious disease (medical specialty)OutbreakInterferoninnate immunityBst2Viral EvasionIsgOrf7aSars-cov-2

Sustainable Development Goals

SDG 0: Good health and well-being

Additional file 1 of The detectable anti-interferon-γ autoantibodies in COVID-19 patients may be associated with disease severity

10.6084/m9.figshare.22611241.v1figshare

Additional file 1 of The detectable anti-interferon-γ autoantibodies in COVID-19 patients may be associated with disease severity

10.6084/m9.figshare.22611241figshare

Additional file 2 of The detectable anti-interferon-γ autoantibodies in COVID-19 patients may be associated with disease severity

10.6084/m9.figshare.22611244.v1figshare

Additional file 2 of The detectable anti-interferon-γ autoantibodies in COVID-19 patients may be associated with disease severity

10.6084/m9.figshare.22611244figshare