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Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

Science(2020)10.1126/science.abd4570Source: DataRank Database

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19 is a research paper published in Science (2020). On theSindex it has a DataRank of 5.6. It has been cited 2,400 times, with 100 citing works in its 1-hop citation network.

N/A

5.6DataRank · unranked

Scored on demand from live citation data

Deposits data Open Access2,400 citations · 100 citing works in its network

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Linked data & code

gen gisaid

Data availability

Repositories this paper deposited data in (declared in PubMed).

Dryad10.5061/dryad.8pk0p2nkk

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (26 grants)Impact (FWCI 142.79)OA: hybridTopics (42)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 21%Citation Network 79%

Base Score Contribution

1.2

From this paper's citation signal

Citation Network Contribution

4.5

From 100 citing papers with measurable signal

Learn more about DataRank methodology →

Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 100 citers.

The UCSC Genome Browser database: 2022 update
Nucleic Acids Research2021309 citations24 referencesContributes 0.239
Disease‐Modifying Therapies and Coronavirus Disease 2019 Severity in Multiple Sclerosis
Annals of Neurology2021462 citations36 referencesContributes 0.170
Complement activation and endothelial perturbation parallel COVID-19 severity and activity
Journal of Autoimmunity2020168 citations37 referencesContributes 0.139
Pre-activated antiviral innate immunity in the upper airways controls early SARS-CoV-2 infection in children
Nature Biotechnology2021395 citations51 referencesContributes 0.117
A diamidobenzimidazole STING agonist protects against SARS-CoV-2 infection
Science Immunology2021170 citations44 referencesContributes 0.117

Authors (100)

Paul Bastard ORCID,Zhiyong Liu ORCID,Jérémie Le Pen ORCID,Marcela Moncada‐Vélez ORCID,Jie Chen ORCID

Live enrichment

PubMed:32972995 PMC:PMC7857407 OpenAlex:https://openalex.org/W3087862874

National Institutes of Health

Grant: R01AI088364

French National Research Agency

Grant: ANR-10-IAHU-01

the Integrative Biology of Emerging Infectious Diseases Laboratory of Excellence

Grant: ANR-10-LABX-62-IBEID

National Human Genome Research Institute

Grant: UM1HG006504 and U24HG008956

the French Foundation for Medical Research

Grant: EQU201903007798

NIH Clinical and Translational Science Award

Grant: UL1 TR001866

Emergent Ventures

Grant: fast grant

NIAID NIH HHS

Grant: 75N93019C00051

NIAID NIH HHS

Grant: U19 AI111825

MRF_

Grant: C0483

NHLBI NIH HHS

Grant: R35 HL135834

NCATS NIH HHS

Grant: UL1 TR001873

NIAID NIH HHS

Grant: HHSN272201800048C

NIAID NIH HHS

Grant: U19 AI135972

NHGRI NIH HHS

Grant: U24 HG008956

NIAID NIH HHS

Grant: R01 AI091707

NIAID NIH HHS

Grant: HHSN272201400008C

NIAID NIH HHS

Grant: P01 AI138938

NCATS NIH HHS

Grant: UL1 TR001863

Medical Research Council

Grant: MR/S032304/1

NIAID NIH HHS

Grant: U19 AI142733

NHGRI NIH HHS

Grant: UM1 HG006504

National Center for Advancing Translational Sciences

Howard Hughes Medical Institute

ST. GILES FOUNDATION

Rockefeller University

FWCI

142.79

Citation Percentile

1.0%

Citation Trend

2020

2021

2022

2023

2024

2025

2026

hybridLicense: cc-by

journalhttps://www.science.org/cms/asset/1b8404d6-b704-443a-855e-2b16d16c140b/pap.pdf

publisherhttps://www.science.org/cms/asset/1b8404d6-b704-443a-855e-2b16d16c140b/pap.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1126/science.abd4570

publisherhttps://www.science.org/doi/pdf/10.1126/science.abd4570

journalhttps://doi.org/10.1126/science.abd4570

Fields of Study

Immunodeficiency and Autoimmune DisordersBlood disorders and treatmentsDiabetes and associated disorders

MeSH Terms

BetacoronavirusLoss of Function MutationCOVID-19SARS-CoV-2AdolescentAdultAgedAged, 80 and overAllelesChildChild, PreschoolFemaleHumansInfantInterferon Type IMaleMiddle AgedPneumonia, ViralCoronavirus InfectionsGenetic Predisposition to DiseaseInterferon Regulatory Factor-7Toll-Like Receptor 3Receptor, Interferon alpha-betaYoung AdultGenetic LociAsymptomatic InfectionsPandemics

Keywords

Coronavirus disease 2019 (COVID-19)Immunity2019-20 coronavirus outbreakSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)MedicineImmunologyVirologyImmune systemInternal medicineInfectious disease (medical specialty)DiseaseOutbreak

Sustainable Development Goals

SDG 0: Good health and well-being