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Structure-Based Engineering of a Sesquiterpene Cyclase to Generate an Alcohol Product: Conversion of epi-Isozizaene Synthase into α-Bisabolol Synthase

Biochemistry(2024)10.1021/acs.biochem.3c00681Source: DataRank Database

Structure-Based Engineering of a Sesquiterpene Cyclase to Generate an Alcohol Product: Conversion of epi-Isozizaene Synthase into α-Bisabolol Synthase is a research paper published in Biochemistry (2024). On theSindex it has a DataRank of 0. It has been cited 3 times.

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Open Access3 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (6 grants)Impact (FWCI 0.63)OA: greenTopics (27)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (2)

David W. Christianson ORCID,Samuel A. Eaton ORCID

Live enrichment

PubMed:38420671 OpenAlex:https://openalex.org/W4392293395

Biological and Environmental Research

Grant: KP1605010

National Institute of General Medical Sciences

Grant: GM56838

National Institute of General Medical Sciences

Grant: P30GM133893

National Institute of General Medical Sciences

Grant: T32 GM132039-03

NIGMS NIH HHS

Grant: R01 GM056838

NIGMS NIH HHS

Grant: T32 GM132039

FWCI

0.63

Citation Percentile

0.6%

Citation Trend

2024

2025

2026

greenLicense: https://doi.org/10.15223/policy-029

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10961106/pdf/nihms-1977970.pdf

publisherhttps://pubs.acs.org/doi/pdf/10.1021/acs.biochem.3c00681

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/10961106

journalhttps://doi.org/10.1021/acs.biochem.3c00681

Fields of Study

Plant biochemistry and biosynthesisMicrobial Natural Products and BiosynthesisMicrobial Metabolic Engineering and BioproductionSesquiterpenesMonocyclic SesquiterpenesCarbon-Carbon Lyases

MeSH Terms

Monocyclic SesquiterpenesSesquiterpenesCarbon-Carbon Lyases

Keywords

CarbocationATP synthaseCyclaseChemistryStereochemistrySesquiterpeneActive siteFarnesyl pyrophosphateStreptomyces coelicolorHydroxylationStreptomyces clavuligerusMutagenesisMevalonate pathwayBiochemistryBiosynthesisMutantEnzymeOrganic chemistry

Sustainable Development Goals

SDG 0: Clean water and sanitation