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Exploring Extended Warheads toward Developing Cysteine-Targeted Covalent Kinase Inhibitors

Journal of Chemical Information and Modeling(2024)10.1021/acs.jcim.4c00890Source: DataRank Database

Exploring Extended Warheads toward Developing Cysteine-Targeted Covalent Kinase Inhibitors is a research paper published in Journal of Chemical Information and Modeling (2024). On theSindex it has a DataRank of 0.350. It has been cited 7 times, with 6 citing works in its 1-hop citation network.

N/A

0.350DataRank · unranked

Scored on demand from live citation data

Open Access7 citations · 6 citing works in its network

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Linked data & code

pdb doi

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Impact (FWCI 1.62)OA: hybridTopics (21)IDs (PubMed, PMC, OpenAlex)Annotations (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 89%Citation Network 11%

Base Score Contribution

0.312

From this paper's citation signal

Citation Network Contribution

0.0382

From 3 citing papers with measurable signal

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Authors (2)

Philip E. Bourne ORCID,Zheng Zhao ORCID

Live enrichment

PubMed:39656065 PMC:PMC11684028 OpenAlex:https://openalex.org/W4405240652

FWCI

1.62

Citation Percentile

0.8%

Citation Trend

2025

2026

hybridLicense: cc-by

journalhttps://pubs.acs.org/doi/pdf/10.1021/acs.jcim.4c00890?ref=article_openPDF

publisherhttps://pubs.acs.org/doi/pdf/10.1021/acs.jcim.4c00890?ref=article_openPDF

publisherhttps://pubs.acs.org/doi/pdf/10.1021/acs.jcim.4c00890

journalhttps://doi.org/10.1021/acs.jcim.4c00890

repositoryhttps://pubmed.ncbi.nlm.nih.gov/39656065

Fields of Study

Click Chemistry and ApplicationsProtein Degradation and InhibitorsComputational Drug Discovery Methods

MeSH Terms

Binding SitesCysteineHumansModels, MolecularProtein KinasesDrug DesignProtein Kinase Inhibitors

Keywords

CysteineChemistryCovalent bondKinaseBiochemistryPharmacologyEnzymeComputational biologyMedicineBiologyOrganic chemistry

Exploring Extended Warheads toward Developing Cysteine-Targeted Covalent Kinase Inhibitors

FAIR Checklist

DataRank Breakdown

Authors (2)

Impact

Open Access

Topics

Annotations (Europe PMC)