Stephen C. Mack

Also affiliated with University of Alabama at Birmingham

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 2%percentile

1.9Author DataRank

Indexed papers

7in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 7 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

OpenPBTA: The Open Pediatric Brain Tumor Atlas

Cell Genomics(2023)10.1016/j.xgen.2023.100340

Top 16%

1.3DataRank

Top 16%62 citations

Krutika S. Gaonkar, Stephanie J. Spielman, Candace L. Savonen, Chanté J. Bethell, Run Jin +61 more

Papers

Driven by 29 papers — median percentile 22. Top paper: “Histone serotonylation regulates ependymoma tumorigenesis”.

Histone serotonylation regulates ependymoma tumorigenesis

Nature(2024)10.1038/s41586-024-07751-z

N/A

1.3DataRank · unranked

53 citations

Peihao He, Malcolm F. McDonald, Michael R. Williamson, Srinidhi Varadharajan, Brittney Lozzi +15 more

OpenPBTA: The Open Pediatric Brain Tumor Atlas

Cell Genomics(2023)10.1016/j.xgen.2023.100340

Top 16%

1.3DataRank

Top 16%62 citations

Krutika S. Gaonkar, Stephanie J. Spielman, Candace L. Savonen, Chanté J. Bethell, Run Jin +61 more

Purine synthesis promotes maintenance of brain tumor initiating cells in glioma

Nature Neuroscience(2017)10.1038/nn.4537

N/A

0.808DataRank · unranked

218 citations

Kailin Yang, Qi Xie, Qiulian Wu, Stephen C. Mack, Yu Shi +19 more

Histone H3.3G34-Mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis

Cell(2020)10.1016/j.cell.2020.11.012

N/A

0.798DataRank · unranked

203 citations

Shriya Deshmukh, Selin Jessa, Djihad Hadjadj, Véronique Lisi, Augusto Faria Andrade +59 more

Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma

Cell(2020)10.1016/j.cell.2020.04.047

N/A

0.743DataRank · unranked

141 citations

Sachin Kumar, Leo J.Y. Kim, Florence M.G. Cavalli, David Przelicki, John Wojcik +61 more

ZFTA–RELA Dictates Oncogenic Transcriptional Programs to Drive Aggressive Supratentorial Ependymoma

Cancer Discovery(2021)10.1158/2159-8290.cd-20-1066

N/A

0.681DataRank · unranked

93 citations

Yanhua Zhao, Srinidhi Varadharajan, Hsiao‐Chi Chen, Selin Jessa, Bryan Rivas +36 more

A road map for the treatment of pediatric diffuse midline glioma

Cancer Cell(2023)10.1016/j.ccell.2023.11.002

N/A

0.653DataRank · unranked

24 citations

Wajd N. Al‐Holou, Marta M. Alonso, Jamie N. Anastas, Pratiti Bandopadhayay, Tara Barron +70 more

H3.3 G34W Promotes Growth and Impedes Differentiation of Osteoblast-Like Mesenchymal Progenitors in Giant Cell Tumor of Bone

Cancer Discovery(2020)10.1158/2159-8290.cd-20-0461

N/A

0.648DataRank · unranked

74 citations

Nicolas Jay, Shriya Deshmukh, Liam D. Hendrikse, Wajih Jawhar, Carol Chen +26 more

Targeting NAD+ Biosynthesis Overcomes Panobinostat and Bortezomib-Induced Malignant Glioma Resistance

Molecular Cancer Research(2020)10.1158/1541-7786.mcr-19-0669

N/A

0.494DataRank · unranked

26 citations

Daniel R. Premkumar, Swetha Thambireddy, Brian Golbourn, Sameer Agnihotri, Kelsey C. Bertrand +8 more

ZIC1 is a context-dependent medulloblastoma driver in the rhombic lip

Nature Genetics(2025)10.1038/s41588-024-02014-z

N/A

0.385DataRank · unranked

12 citations

Ran Tao, Zhen You, Parthiv Haldipur, Anders W. Erickson, Hamza Farooq +66 more

OpenPBTA: An Open Pediatric Brain Tumor Atlas

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.09.13.507832

Top 49%

0.363DataRank

Top 49%7 citations

Krutika S. Gaonkar, Candace L. Savonen, Stephanie J. Spielman, Chanté J. Bethell, Run Jin +59 more

Integrated transcriptomic landscape of medulloblastoma and ependymoma reveals novel tumor subtype-specific biology

Neuro-Oncology(2025)10.1093/neuonc/noaf251

Top 72%

0.112DataRank

Top 72%1 citations

Nicholas Nuechterlein, Matt Jensen, Gregory Glatzer, Philipp Sievers, Srinidhi Varadharajan +7 more

Data underlying OpenPBTA Manuscript Figures and Molecular Alterations

Zenodo (CERN European Organization for Nuclear Research)(2023)10.5281/zenodo.7805407

Top 78%

0.104DataRank

Top 78%1 citations

Krutika S. Gaonkar, Stephanie J. Spielman, Candace L. Savonen, Chanté J. Bethell, Run Jin +63 more

Integrated transcriptomic landscape of medulloblastoma and ependymoma reveals novel tumor subtype-specific biology

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.10.21.619495

Top 78%

0.104DataRank

Top 78%1 citations

Nicholas Nuechterlein, Matt Jensen, Gregory Glatzer, Philipp Sievers, Srinidhi Varadharajan +7 more

Mutant IDH silences GSX2 to reprogram neural progenitor cell fate and promote gliomagenesis

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.08.12.667486

N/A

0.104DataRank · unranked

1 citations

Diana D. Shi, Lei Guo, Ethan Neumann, Michael M. Levitt, Pranita Kaphle +28 more

Sox9 directs divergent epigenomic states in brain tumor subtypes

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2202015119

N/A

0DataRank · unranked

26 citations

Hsiao‐Chi Chen, Amanda Reyes, Srinidhi Varadharajan, Antrix Jain, Carrie Mohila +10 more

Author Correction: Loss of MAT2A compromises methionine metabolism and represents a vulnerability in H3K27M mutant glioma by modulating the epigenome

Nature Cancer(2022)10.1038/s43018-022-00407-9

N/A

0DataRank · unranked

2 citations

Matthew Halbert, Katharine Halligan, Srinidhi Varadharajan, Brian Krug, Nneka E. Mbah +44 more

Hijacking a neurodevelopmental epigenomic program in metastatic dissemination of medulloblastoma

Research Square(2022)10.21203/rs.3.rs-1270726/v1

N/A

0DataRank · unranked

0 citations

Bradley Poore, Emily Brown, Jieqi Qian, Bin Xie, Evridiki Asimakidou +35 more

Leveraging epigenomic patterns to resolve the heterogeneity and origins of CNS germ cell tumors

Neuro-Oncology(2022)10.1093/neuonc/noac102

N/A

0DataRank · unranked

0 citations

Stephen C. Mack, Srinidhi Varadharajan

In vivo functional genomics identifies essentiality of potassium homeostasis in medulloblastoma

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.07.23.501234

N/A

0DataRank · unranked

0 citations

Xin Wang, Anders W. Erickson, Patryk Skowron, Xian Wang, Xin Chen +29 more

The Meningioma Enhancer Landscape Delineates Novel Subgroups and Drives Druggable Dependencies

Cancer Discovery(2020)10.1158/2159-8290.cd-20-0160

N/A

0DataRank · unranked

59 citations

Harish N. Vasudevan, Deobrat Dixit, Jean Bernatchez, Qiulian Wu, Lisa C. Wallace +19 more

GRP78-CAR T cell effector function against solid and brain tumors is controlled by GRP78 expression on T cells

Cell Reports Medicine(2023)10.1016/j.xcrm.2023.101297

N/A

0DataRank · unranked

28 citations

Nikhil Hebbar, Unmesha Thanekar, Zhongzhen Yi, Haley Houke, Meghan B Ward +8 more

Locoregional delivery of CAR T cells to the cerebrospinal fluid for treatment of metastatic medulloblastoma and ependymoma

Nature Medicine(2020)10.1038/s41591-020-0827-2

N/A

0DataRank · unranked

242 citations

Alberto Delaidelli, Sujith K. Joseph, Kevin Bielamowicz, Kristen Fousek, Borja Holgado +51 more

An ERK5-PFKFB3 axis regulates glycolysis and represents a therapeutic vulnerability in pediatric diffuse midline glioma

Cell Reports(2023)10.1016/j.celrep.2023.113557

N/A

0DataRank · unranked

17 citations

Taylor Gatesman, Akanksha Chilukuri, Srinidhi Varadharajan, Brenden J. Johnson, Daniel R. Premkumar +39 more

Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αvβ5 Axis

Cell stem cell(2020)10.1016/j.stem.2019.11.016

N/A

0DataRank · unranked

185 citations

Pinar Mesci, Jean Bernatchez, Ryan C. Gimple, Xiuxing Wang, Simon T. Schafer +29 more

Data underlying OpenPBTA Manuscript Figures and Molecular Alterations

Zenodo (CERN European Organization for Nuclear Research)(2023)10.5281/zenodo.7805408

Top 100%

0DataRank

Top 100%0 citations

Krutika S. Gaonkar, Stephanie J. Spielman, Candace L. Savonen, Chanté J. Bethell, Run Jin +63 more

Data underlying OpenPBTA Manuscript Figures and Molecular Alterations

Zenodo (CERN European Organization for Nuclear Research)(2023)10.5281/zenodo.7877739

Top 100%

0DataRank

Top 100%0 citations

Krutika S. Gaonkar, Stephanie J. Spielman, Candace L. Savonen, Chanté J. Bethell, Run Jin +63 more

Therapeutic Impact of Cytoreductive Surgery and Irradiation of Posterior Fossa Ependymoma in the Molecular Era: A Retrospective Multicohort Analysis

UNC Libraries(2020)10.17615/cy5h-9p96

N/A

0DataRank · unranked

0 citations

Sama Ahsan, Erwin G. Van Meir, Miguel A. Guzmán, Amulya A. Nageswara Rao, Uri Tabori +95 more

Loss of MAT2A compromises methionine metabolism and represents a vulnerability in H3K27M mutant glioma by modulating the epigenome

Nature Cancer(2022)10.1038/s43018-022-00348-3

N/A

0DataRank · unranked

92 citations

Matthew Halbert, Katharine Halligan, Srinidhi Varadharajan, Brian Krug, Nneka E. Mbah +44 more

Stephen C. Mack

Indexed papers

Top data-sharing exemplar

Papers