A deep catalogue of protein-coding variation in 983,578 individuals is a dataset published in Nature (2024). On theSindex it has a DataRank of 1.9, placing it in the top 11.4% of the data-sharing corpus. It has been cited 109 times, with 100 citing works in its 1-hop citation network. Its calibrated FAIR score is 25/100.
Ranks in the top 11% for downstream scientific impact
DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?
FAIR checklist signals are shown for context only and do not affect DataRank scoring.
Full FAIR picture · advisory
The headline score is computed from the scored criteria — the fact-shaped checks (a repository, an accession, a licence) that two independent models agree on. The advisory criteria below are real FAIR guidance but rest on judgment calls that models read differently, so they inform without moving the number.
“https://rgc-research.regeneron.com/me/home”— not found in the paper; verdict downgraded
The identifier for the main dataset is a web URL, not a persistent identifier scheme. [downgraded to 'no' — no verifiable quote from the paper] [majority verdict 'no' (4/5 passes agreed)]
RDA-F1-01D — FAIR Data Maturity Model: 'Data is identified by a persistent identifier' (priorit · RDA-F1-02D — FAIR Data Maturity Model: 'Data is identified by a globally unique identifier' · FsF-F1-02D — F-UJI/FAIRsFAIR: 'Data is assigned a persistent identifier'
“Genetic variation data for 821,979 unrelated individuals are made publicly available through the RGC-ME browser (https://rgc-research.regeneron.com/me/home).”— not found in the paper; verdict downgraded
The named holder is the RGC-ME browser, a project website, not a standard data repository. [downgraded to 'no' — no verifiable quote from the paper] [majority verdict 'no' (4/5 passes agreed)]
RDA-F4-01M — FAIR Data Maturity Model: metadata is offered so it can be harvested and indexed ( · NIH DMS Policy Element 4 (NOT-OD-21-014) — name the repository where data will be archived · NSTC Desirable Characteristics of Data Repositories (2022) — 'Long-Term Sustainability', 'Reten
“Genetic variation data for 821,979 unrelated individuals are made publicly available through the RGC-ME browser (https://rgc-research.regeneron.com/me/home).”— not found in the paper; verdict downgraded
The dataset's identifier (the browser URL) appears only in the body text, not as a reference-list entry. [downgraded to 'no' — no verifiable quote from the paper] [majority verdict 'no' (4/5 passes agreed)]
FORCE11 Joint Declaration of Data Citation Principles (2014) — data should be cited as a first- · RDA-F3-01M — metadata clearly and explicitly includes the identifier of the data it describes · FsF-F3-01M — F-UJI: 'Metadata includes the identifier of the data it describes'
Advisory · not in the published score
“Genetic variation data for 821,979 unrelated individuals are made publicly available through the RGC-ME browser (https://rgc-research.regeneron.com/me/home).”— not found in the paper; verdict downgraded
The data-availability statement points to a web browser URL, not a repository record with an accession. [downgraded to 'no' — no verifiable quote from the paper] [majority verdict 'no' (3/5 passes agreed)]
Colavizza, Hrynaszkiewicz, Staden, Whitaker & McGillivray (2020), 'The citation advantage of li · Springer Nature research data policy — Data Availability Statements: standard statement templat · RDA-F3-01M — metadata clearly and explicitly includes the identifier of the data it describes
“The catalogue includes more than 10.4 million missense and 1.1 million predicted loss-of-function (pLOF) variants.”
The dataset's content is described in running prose, not in an itemised inventory. [majority verdict 'partial' (3/5 passes agreed)]
RDA-F2-01M — 'Rich metadata is provided to allow discovery' (priority Essential) · FsF-F2-01M — F-UJI: 'Metadata includes descriptive core elements to support data findability' · FsF-R1-01MD — F-UJI: 'Metadata specifies the content of the data'
“Genetic variation data for 821,979 unrelated individuals are made publicly available through the RGC-ME browser (https://rgc-research.regeneron.com/me/home).”— not found in the paper; verdict downgraded
The data are stated to be publicly available with no precondition or barrier. [downgraded to 'partial' — no verifiable quote from the paper]
RDA-A1.1-01D — 'Data is accessible through a free access protocol' · FsF-A1-01M — F-UJI: 'Metadata contains access level and access conditions of the data' · NSTC Desirable Characteristics of Data Repositories (2022) — 'Free and Easy Access'
Advisory · not in the published score
“Genetic variation data for 821,979 unrelated individuals are made publicly available through the RGC-ME browser (https://rgc-research.regeneron.com/me/home).”— not found in the paper; verdict downgraded
The paper explicitly labels the data as 'publicly available', which is a clear access-level label. [downgraded to 'partial' — no verifiable quote from the paper] [majority verdict 'partial' (4/5 passes agreed)]
FsF-A1-01M — F-UJI: 'Metadata contains access level and access conditions of the data' · RDA-A1-01M — metadata contains information to enable the user to get access to the data · COAR Controlled Vocabularies — Access Rights v1.0 (open / embargoed / restricted / metadata-onl
The main dataset is publicly available with no gatekeeper named; the paper does not address a controlled-access procedure for the primary catalogue. [majority verdict 'no' (4/5 passes agreed)]
NIH Genomic Data Sharing Policy (NOT-OD-14-124) — controlled-access via a Data Access Committee · RDA-A1.2-01D — 'Data is accessible through an access protocol that supports authentication and · NIH DMS Policy Element 5 (NOT-OD-21-014) — Access, Distribution, or Reuse Considerations (conse
“Genetic variation data for 821,979 unrelated individuals are made publicly available through the RGC-ME browser (https://rgc-research.regeneron.com/me/home).”— not found in the paper; verdict downgraded
The statement indicates availability now but does not specify how long the data will persist. [downgraded to 'no' — no verifiable quote from the paper]
NIH DMS Plan Element 4 (NOT-OD-21-014) — Data Preservation, Access, and Associated Timelines · NSTC Desirable Characteristics (2022), Organizational Infrastructure: 'Retention Policy' · RDA-A2-01M — 'Metadata is guaranteed to remain available after data is no longer available'
“In addition, vcf files can be downloaded from the web portal.”
VCF is an open, community-standard format for genetic variation data.
FsF-R1.3-02D — F-UJI: 'Data is available in a file format recommended by the target research co · RDA-R1.3-02D — data is expressed in a machine-understandable community standard · RDA-I1-01D — data uses a knowledge representation expressed in a standardised format
Advisory · not in the published score
No data or metadata community standard (e.g., MIAME, ISA-Tab, an ontology) is named for the dataset. [majority verdict 'no' (4/5 passes agreed)]
RDA-R1.3-01M — 'Metadata complies with a community standard' (priority Essential) · RDA-R1.3-01D — 'Data complies with a community standard' · RDA-I2-01M — '(Meta)data use vocabularies that follow FAIR principles'
“The human reference genome GRCh38 can be obtained from ftp://ftp-trace.ncbi.nlm.nih.gov/1000genomes/ftp/technical/reference/GRCh38_reference_genome/GRCh38_full_analysis_set_plus_decoy_hla.fa.”— not found in the paper; verdict downgraded
The paper provides an identifier (URL) for the reference genome used in the study. [downgraded to 'no' — no verifiable quote from the paper]
RDA-I3-01M — '(meta)data include references to other (meta)data' · RDA-I3-03M — 'metadata includes qualified references to other metadata' · FsF-I3-01M — F-UJI: 'Metadata includes links between the data and its related entities'
No reuse licence is mentioned for the data; the CC BY licence applies only to the article.
RDA-R1.1-01M — 'Metadata includes information about the licence under which the data can be reu · RDA-R1.1-02M — 'Metadata refers to a standard reuse licence' · RDA-R1.1-03M — 'Metadata refers to a machine-understandable reuse licence'
No version token or date is given for the RGC-ME dataset snapshot.
DataCite Metadata Schema 4.6 — the 'Version' property · RDA-R1.2-01M — provenance information (which version was used is provenance) · NSTC Desirable Characteristics of Data Repositories (2022) — 'Provenance', 'Retention Policy'
“Custom code to generate LOF projection curves is available at https://github.com/rgcgithub/rgc_me_analysis.”— not found in the paper; verdict downgraded
A machine-resolvable code repository URL is provided for the study's own code. [downgraded to 'partial' — no verifiable quote from the paper]
NIH DMS Policy Element 2 (NOT-OD-21-014) — 'Related Tools, Software and/or Code' · FAIR4RS Principles v1.0 (Chue Hong et al., 2022; RDA/FORCE11/ReSA) — FAIR Principles for Resear · FORCE11 Software Citation Principles (Smith, Katz & Niemeyer, 2016, PeerJ CS 2:e86)
“ZIA-MH002843”
The paper gives an award/grant number (ZIA-MH002843) from the National Institute of Mental Health.
DataCite Metadata Schema 4.6 — 'FundingReference' property (funderName, funderIdentifier, award · Crossref Funder Registry — canonical funder identifiers for funding metadata · RDA-F2-01M — rich metadata provided to allow discovery (funding is part of the descriptive reco
Advisory · not in the published score
“sequencing reads were generated using bcl2fastq v.2.20 and were mapped to references using BWA-MEM v.0.7.17.”
The paper names specific software and versions used to generate the data.
RDA-R1.2-01M — 'Metadata includes provenance information according to community- specific standa · FsF-R1.2-01M — F-UJI: 'Metadata includes provenance information about data creation or generati · W3C PROV-O (W3C Recommendation, 2013) — the entity/activity/agent model of provenance
No documentation object (e.g., README, data dictionary) is named as accompanying the data. [majority verdict 'no' (3/5 passes agreed)]
RDA-R1-01M — '(Meta)data are richly described with a plurality of accurate and relevant attribu · FsF-R1-01MD — F-UJI: 'Metadata specifies the content of the data' · NIH DMS Policy Element 3 (NOT-OD-21-014) — Standards (documentation and metadata to accompany t
Calibrated FAIR score — a parallel quality metric, independent of the DataRank citation score. See the full evaluation →
Base Score Contribution
0.705
From this paper's citation signal
Citation Network Contribution
1.2
From 56 citing papers with measurable signal
Ranked by each citer's contribution to N(p) — log1p(Cq) divided by its reference count — out of 100 citers.
Intramural NIH HHS
Grant: ZIA MH002843
NCI NIH HHS
Grant: R01 CA157823
Medical Research Council
Grant: MR/Z504543/1
NCI NIH HHS
Grant: R01 CA201358
National Institutes of Health
Grant: 5R01CA157823-08
Genetic Susceptibility and Biomarkers of Platinum-related Toxicities
National Institutes of Health
Grant: 1ZIAMH002843-07
Genetic Linkage and Association in Bipolar Disorder
FWCI
17.97
Citation Percentile
1.0%
Influential Citations
13
Citation Trend
Fields of Study
MeSH Terms
Keywords
Sustainable Development Goals