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Chemical acylation of an acquired serine suppresses oncogenic signaling of K-Ras(G12S)

Nature Chemical Biology(2022)10.1038/s41589-022-01065-9Source: DataRank Database

Chemical acylation of an acquired serine suppresses oncogenic signaling of K-Ras(G12S) is a research paper published in Nature Chemical Biology (2022). On theSindex it has a DataRank of 0. It has been cited 149 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access149 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (9 grants)Impact (FWCI 10.43)OA: hybridTopics (52)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (3)

Keelan Z. Guiley ORCID,Kevan M. Shokat ORCID,Ziyang Zhang ORCID

Live enrichment

PubMed:35864332 PMC:PMC9596369 OpenAlex:https://openalex.org/W4286203125

U.S. Department of Health & Human Services | National Institutes of Health

Grant: R01CA244550

Damon Runyon Cancer Research Foundation

Grant: DRG-2281-17

Damon Runyon Cancer Research Foundation

Grant: DRG-2399-20

National Institutes of Health

Grant: 5R01CA244550-03

Inhibitors of the G protein GNAS which drives pancreatic tumorigenesis

Fundação para a Ciência e a Tecnologia, I.P.

Grant: PTDC/CCI-INF/6762/2020

MS3: New foundations for micro-services and serverless systems

Howard Hughes Medical Institute

Samuel Waxman Cancer Research Foundation

The Emerald Foundation The Mark Foundation

Howard Hughes Medical Institute

FWCI

10.43

Citation Percentile

1.0%

Citation Trend

2022

2023

2024

2025

2026

hybridLicense: cc-by

journalhttps://www.nature.com/articles/s41589-022-01065-9.pdf

publisherhttps://www.nature.com/articles/s41589-022-01065-9.pdf

publisherhttps://www.nature.com/articles/s41589-022-01065-9

journalhttps://doi.org/10.1038/s41589-022-01065-9

repositoryhttps://pubmed.ncbi.nlm.nih.gov/35864332

Fields of Study

Protein Kinase Regulation and GTPase SignalingBiochemical and Molecular ResearchPI3K/AKT/mTOR signaling in cancer0301 basic medicine0303 health sciences03 medical and health sciencesHumansCysteineSerineProto-Oncogene Proteins p21(ras)MutationOncogenesAcylation

MeSH Terms

AcylationCysteineHumansMutationOncogenesSerineProto-Oncogene Proteins p21(ras)

Keywords

KRASSerineSmall moleculeMutantSomatic cellPoint mutationOncogeneCysteineCancer researchBiologyMutationChemistryCell biologyGeneticsBiochemistryGenePhosphorylationEnzymeBiochemistry & Molecular BiologyAcylation610OncogenesArticleProto-Oncogene Proteins p21(ras)Medicinal and Biomolecular ChemistryOrphan DrugRare Diseases5.1 PharmaceuticalsHumansBiochemistry and Cell BiologyDevelopment of treatments and therapeutic interventionsCancer

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being