Kevan M. Shokat

Also affiliated with University of California System

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 62 papers. Top paper: “Targets of the cyclin-dependent kinase Cdk1”.

Targets of the cyclin-dependent kinase Cdk1

Nature(2003)10.1038/nature02062

N/A

15.0DataRank · unranked

894 citations

Erika L. Woodbury, Phuong N. Quang, Maria Paraz, Justin D. Blethrow, Kavita Shah +3 more

A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.03.22.002386

N/A

14.3DataRank · unranked

456 citations

Gwendolyn M. Jang, Mehdi Bouhaddou, Jiewei Xu, Kirsten Obernier, Matthew J. O’Meara +95 more

The Global Phosphorylation Landscape of SARS-CoV-2 Infection

Cell(2020)10.1016/j.cell.2020.06.034

N/A

10.3DataRank · unranked

1152 citations

Danish Memon, Bjoern Meyer, Kris M. White, Veronica V. Rezelj, Miguel Correa Marrero +73 more

Plitidepsin has potent preclinical efficacy against SARS-CoV-2 by targeting the host protein eEF1A

Science(2021)10.1126/science.abf4058

N/A

9.0DataRank · unranked

365 citations

Romel Rosales, Soner Yildiz, Thomas Kehrer, Lisa Miorin, Elena Moreno +21 more

Evolution of enhanced innate immune evasion by the SARS-CoV-2 B.1.1.7 UK variant

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.06.06.446826

N/A

5.0DataRank · unranked

107 citations

Mehdi Bouhaddou, Ann‐Kathrin Reuschl, Lorena Zuliani‐Alvarez, Benjamin J. Polacco, Adrian Pelin +28 more

Host-directed therapies against early-lineage SARS-CoV-2 retain efficacy against B.1.1.7 variant

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.01.24.427991

N/A

2.4DataRank · unranked

42 citations

Lucy G. Thorne, Lorena Zuliani‐Alvarez, Mehdi Bouhaddou, Kirsten Obernier, Joseph Hiatt +18 more

Proteomic and genetic analyses of influenza A viruses identify pan-viral host targets

Nature Communications(2023)10.1038/s41467-023-41442-z

N/A

1.2DataRank · unranked

62 citations

Michael McGregor, Mehdi Bouhaddou, Benjamin J. Polacco, Eun‐Young Kim, Thông Nguyen +50 more

Evolution of enhanced innate immune evasion by SARS-CoV-2

Nature(2021)10.1038/s41586-021-04352-y

N/A

0.900DataRank · unranked

402 citations

Mehdi Bouhaddou, Ann-Kathrin Reuschl, Lorena Zuliani-Alvarez, Benjamin J. Polacco, Adrian Pelin +41 more

Drug-induced phospholipidosis confounds drug repurposing for SARS-CoV-2

Science(2021)10.1126/science.abi4708

N/A

0.812DataRank · unranked

224 citations

Veronica V. Rezelj, Benoit Fischer, Audrey Fischer, Matthew J. O’Meara, Blandine Monel +24 more

A covalent inhibitor of K-Ras(G12C) induces MHC class I presentation of haptenated peptide neoepitopes targetable by immunotherapy

Cancer Cell(2022)10.1016/j.ccell.2022.07.005

N/A

0.735DataRank · unranked

133 citations

Peter J. Rohweder, Chayanid Ongpipattanakul, Koli Basu, Markus‐Frederik Bohn, Eli Dugan +5 more

PI4KIIIβ is a therapeutic target in chromosome 1q–amplified lung adenocarcinoma

Science Translational Medicine(2020)10.1126/scitranslmed.aax3772

N/A

0.635DataRank · unranked

68 citations

Priyam Banerjee, Edward A. Pham, Florentine U. Rutaganira, Kaustabh Basu, Neus Bota‐Rabassedas +30 more

A reversible SRC-relayed COX2 inflammatory program drives resistance to BRAF and EGFR inhibition in BRAFV600E colorectal tumors

Nature Cancer(2023)10.1038/s43018-022-00508-5

N/A

0.574DataRank · unranked

45 citations

Chloé E. Atreya, Changjun Wang, Bo Pan, Courtney A. Dreyer, Diede Brunen +20 more

IFITM proteins assist cellular uptake of diverse linked chemotypes

Science(2022)10.1126/science.abl5829

N/A

0.550DataRank · unranked

38 citations

Douglas R. Wassarman, Tangpo Yang, YiTing Paung, Ziyang Zhang, Thomas O’loughlin +9 more

mTOR inhibition reprograms cellular proteostasis by regulating eIF3D-mediated selective mRNA translation and promotes cell phenotype switching

Cell Reports(2023)10.1016/j.celrep.2023.112868

N/A

0.505DataRank · unranked

28 citations

Min-Joon Han, Mark P. Jedrychowski, Ziyang Zhang, Kevan M. Shokat, David R. Plas +3 more

Direct Modulators of K-Ras–Membrane Interactions

ACS Chemical Biology(2023)10.1021/acschembio.3c00413

N/A

0.483DataRank · unranked

24 citations

Rebika Shrestha, Que N. Van, César A. López, Neha Arora, Marco Tonelli +8 more

Targeting a splicing-mediated drug resistance mechanism in prostate cancer by inhibiting transcriptional regulation by PKCβ1

Oncogene(2022)10.1038/s41388-022-02179-z

N/A

0.434DataRank · unranked

17 citations

Veronica Steri, Hao G. Nguyen, Yeonjoo Hwang, John D. Gordan, Byron Hann +3 more

Genome-scale CRISPR screens identify PTGES3 as a direct modulator of androgen receptor function in advanced prostate cancer

Nature Genetics(2025)10.1038/s41588-025-02388-8

N/A

0.312DataRank · unranked

7 citations

James E. Melnyk, Becky Xu Hua Fu, Raunak Shrestha, Meng Zhang, Martin Sjöström +34 more

Phospholipidosis is a shared mechanism underlying the in vitro antiviral activity of many repurposed drugs against SARS-CoV-2

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.03.23.436648

N/A

0.292DataRank · unranked

6 citations

Veronica V. Rezelj, Benoit Fischer, Audrey Fischer, Matthew J. O’Meara, Blandine Monel +18 more

Chemical Genetic Identification of PKC Epsilon Substrates in Mouse Brain

Molecular & Cellular Proteomics(2023)10.1016/j.mcpro.2023.100522

N/A

0.241DataRank · unranked

4 citations

Laura B. Ferguson, Nicholas T. Hertz, Robert J. Chalkley, Alma L. Burlingame, Kevan M. Shokat +3 more

HBV Remodels PP2A Complexes to Rewire Kinase Signaling in Hepatocellular Carcinoma

Cancer Research(2024)10.1158/0008-5472.can-24-0456

N/A

0.218DataRank · unranked

3 citations

Adriana Pitea, Gwendolyn M. Jang, Zhong Xu, Huat Chye Lim, Alex L. Choi +22 more

KRAS is vulnerable to reversible switch-II pocket engagement in cells

Nature Chemical Biology(2022)10.1038/s41589-022-00985-w

N/A

0DataRank · unranked

111 citations

D. Matthew Peacock, Qinheng Zheng, Joel A. Walker, Ziyang Zhang, Chad Zimprich +7 more

Brain-restricted mTOR inhibition with binary pharmacology

Nature(2022)10.1038/s41586-022-05213-y

N/A

0DataRank · unranked

86 citations

Qi-Wen Fan, Xujun Luo, Kevin Lou, William A. Weiss, Kevan M. Shokat +1 more

State-selective modulation of heterotrimeric Gαs signaling with macrocyclic peptides

Cell(2022)10.1016/j.cell.2022.09.019

N/A

0DataRank · unranked

64 citations

Qi Hu, Rong Gao, Emily E. Blythe, Kouki K Touhara, Hayden Peacock +5 more

Cold shock domain–containing protein E1 is a posttranscriptional regulator of the LDL receptor

Science Translational Medicine(2022)10.1126/scitranslmed.abj8670

N/A

0DataRank · unranked

23 citations

Arun Padmanabhan, Bryan H. Lau, Akhil Pampana, Li Li, Clara Youngna Lee +12 more

Tissue-restricted inhibition of mTOR using chemical genetics

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2204083119

N/A

0DataRank · unranked

8 citations

Kondalarao Bankapalli, Leo J. Pallanck, Kevan M. Shokat, Douglas R. Wassarman

Probing the KRas Switch II Groove by Fluorine NMR Spectroscopy

ACS Chemical Biology(2022)10.1021/acschembio.2c00566

N/A

0DataRank · unranked

11 citations

Mark J. S. Kelly, Kevan M. Shokat, D. Matthew Peacock

Tissue-Restricted Inhibition of mTOR Using Chemical Genetics

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.08.483534

N/A

0DataRank · unranked

1 citations

Kondalarao Bankapalli, Leo J. Pallanck, Kevan M. Shokat, Douglas R. Wassarman

A reversible SRC-relayed COX2-inflammatory program drives therapeutic resistance in BRAF V600E colorectal tumors

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.20.512885

N/A

0DataRank · unranked

0 citations

Chloé E. Atreya, Changjun Wang, Bo Pan, Courtney A. Dreyer, Diede Brunen +20 more

Cellpanelr: identify predictive biomarkers from cell line panel response data

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.11.02.514913

N/A

0DataRank · unranked

0 citations

Taiasean Wu, Kevan M. Shokat, Douglas R. Wassarman

Evolutionarily divergent mTOR remodels translatome for tissue regeneration

Nature(2023)10.1038/s41586-023-06365-1

N/A

0DataRank · unranked

70 citations

Hannah D. Rosenblatt, Leila Shokat, Shizhong Dai, Duygu Kuzuoğlu‐Öztürk, Zijian Zhang +4 more

Protocol for performing and optimizing differential scanning fluorimetry experiments

STAR Protocols(2023)10.1016/j.xpro.2023.102688

N/A

0DataRank · unranked

53 citations

Michael Hornsby, Lawrence Zhu, Joshua C. Yu, Kevan M. Shokat, Jason E. Gestwicki +1 more

Data from Phosphorylation of the src Epithelial Substrate Trask Is Tightly Regulated in Normal Epithelia but Widespread in Many Human Epithelial Cancers

(2023)10.1158/1078-0432.c.6517638

N/A

0DataRank · unranked

0 citations

Frederick L. Baehner, Danislav S. Spassov, Deepika Ahuja, Donghui Wang, Byron Hann +5 more

Data from Phosphorylation of the src Epithelial Substrate Trask Is Tightly Regulated in Normal Epithelia but Widespread in Many Human Epithelial Cancers

(2023)10.1158/1078-0432.c.6517638.v1

N/A

0DataRank · unranked

0 citations

Frederick L. Baehner, Danislav S. Spassov, Deepika Ahuja, Donghui Wang, Byron Hann +5 more

Strain-release alkylation of Asp12 enables mutant selective targeting of K-Ras-G12D

Nature Chemical Biology(2024)10.1038/s41589-024-01565-w

N/A

0DataRank · unranked

74 citations

Ziyang Zhang, Keelan Z. Guiley, Kevan M. Shokat, Qinheng Zheng

Targeting Ras-, Rho-, and Rab-family GTPases via a conserved cryptic pocket

Cell(2024)10.1016/j.cell.2024.08.017

N/A

0DataRank · unranked

56 citations

Victoria Bowcut, Micah C. Fernando, Yue Yang, Lawrence Zhu, Meredith L. Jenkins +12 more

The structure of KRAS G12C bound to divarasib highlights features of potent switch-II pocket engagement

Small GTPases(2024)10.1080/21541248.2025.2505441

N/A

0DataRank · unranked

8 citations

Gregory B. Craven, Kevan M. Shokat, Micah C. Fernando

IL-13 and IL-17A activate β1 integrin through an NF-kB/Rho kinase/PIP5K1γ pathway to enhance force transmission in airway smooth muscle

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2401251121

N/A

0DataRank · unranked

14 citations

Ying Shi, Prescott G. Woodruff, Kevan M. Shokat, William F. DeGrado, Hyunil Jo +3 more

Absence of ABL1 exon 2-encoded SH3 residues in BCR::ABL1 destabilizes the autoinhibited kinase conformation and confers resistance to asciminib

Leukemia(2024)10.1038/s41375-024-02353-0

N/A

0DataRank · unranked

11 citations

RosaAnna DeFilippis, Ian R Outhwaite, Isabelle Kwan, Ji Young Lee, Carlyn Leavitt +11 more

IL-13 and IL-17A Activate β1 Integrin through an NF-kB/Rho kinase/PIP5K1γ pathway to Enhance Force Transmission in Airway Smooth Muscle

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.05.01.592042

N/A

0DataRank · unranked

0 citations

Ying Shi, Prescott G. Woodruff, Kevan M. Shokat, W.F. DeGrado, Hyunil Jo +3 more

Deazaguanylation is a nucleobase-protein conjugation required for type IV CBASS immunity

Science(2025)10.1126/science.adx6053

N/A

0DataRank · unranked

4 citations

Patrick Pfaff, Joao A. Paulo, Steven P. Gygi, Kevan M. Shokat, Philip J. Kranzusch +1 more

Programmable translational inhibition by a molecular glue-oligonucleotide conjugate

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.07.15.664547

N/A

0DataRank · unranked

0 citations

Joanna Kovalski, Francisco J. Zapatero‐Belinchón, Maxwell R. Bennett, Duygu Kuzuoğlu‐Öztürk, Qiongyu Li +9 more

Figure S2 from HBV Remodels PP2A Complexes to Rewire Kinase Signaling in Hepatocellular Carcinoma

Figshare(2025)10.1158/0008-5472.28428328

N/A

0DataRank · unranked

0 citations

Adriana Pitea, Gwendolyn M. Jang, Zhong Xu, Huat Chye Lim, Alex L. Choi +22 more

Single-sequence deep learning delivers crystal-quality models of covalent K-Ras G12 hotspot complexes

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.09.16.676163

N/A

0DataRank · unranked

0 citations

Qinheng Zheng, Kevan M. Shokat, Sungwon Jung

Supplementary text from HBV Remodels PP2A Complexes to Rewire Kinase Signaling in Hepatocellular Carcinoma

(2025)10.1158/0008-5472.28431528

N/A

0DataRank · unranked

0 citations

Adriana Pitea, Gwendolyn M. Jang, Zhong Xu, Huat Chye Lim, Alex L. Choi +22 more

Figure S1 from HBV Remodels PP2A Complexes to Rewire Kinase Signaling in Hepatocellular Carcinoma

Figshare(2025)10.1158/0008-5472.28431549

N/A

0DataRank · unranked

0 citations

Adriana Pitea, Gwendolyn M. Jang, Zhong Xu, Huat Chye Lim, Alex L. Choi +22 more

Supplementary Tables 1-8 from HBV Remodels PP2A Complexes to Rewire Kinase Signaling in Hepatocellular Carcinoma

Figshare(2025)10.1158/0008-5472.28428319

N/A

0DataRank · unranked

0 citations

Adriana Pitea, Gwendolyn M. Jang, Zhong Xu, Huat Chye Lim, Alex L. Choi +22 more

Figure S3 from HBV Remodels PP2A Complexes to Rewire Kinase Signaling in Hepatocellular Carcinoma

Figshare(2025)10.1158/0008-5472.28428325

N/A

0DataRank · unranked

0 citations

Adriana Pitea, Gwendolyn M. Jang, Zhong Xu, Huat Chye Lim, Alex L. Choi +22 more

Figure S3 from HBV Remodels PP2A Complexes to Rewire Kinase Signaling in Hepatocellular Carcinoma

Figshare(2025)10.1158/0008-5472.28431540

N/A

0DataRank · unranked

0 citations

Adriana Pitea, Gwendolyn M. Jang, Zhong Xu, Huat Chye Lim, Alex L. Choi +22 more

Supplementary text from HBV Remodels PP2A Complexes to Rewire Kinase Signaling in Hepatocellular Carcinoma

(2025)10.1158/0008-5472.28428316

N/A

0DataRank · unranked

0 citations

Adriana Pitea, Gwendolyn M. Jang, Zhong Xu, Huat Chye Lim, Alex L. Choi +22 more

HBV rewires liver cancer signaling by altering PP2A complexes

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.15.532845

N/A

0DataRank · unranked

0 citations

Rigney E. Turnham, Manon Eckhardt, Gwendolyn M. Jang, Zhong Xu, Alex Choi +23 more

Data from HBV Remodels PP2A Complexes to Rewire Kinase Signaling in Hepatocellular Carcinoma

(2025)10.1158/0008-5472.c.7676185

N/A

0DataRank · unranked

0 citations

Adriana Pitea, Gwendolyn M. Jang, Zhong Xu, Huat Chye Lim, Alex L. Choi +22 more

Figure S1 from HBV Remodels PP2A Complexes to Rewire Kinase Signaling in Hepatocellular Carcinoma

Figshare(2025)10.1158/0008-5472.28428331

N/A

0DataRank · unranked

0 citations

Adriana Pitea, Gwendolyn M. Jang, Zhong Xu, Huat Chye Lim, Alex L. Choi +22 more

Figure S4 from HBV Remodels PP2A Complexes to Rewire Kinase Signaling in Hepatocellular Carcinoma

Figshare(2025)10.1158/0008-5472.28428322

N/A

0DataRank · unranked

0 citations

Adriana Pitea, Gwendolyn M. Jang, Zhong Xu, Huat Chye Lim, Alex L. Choi +22 more

Figure S4 from HBV Remodels PP2A Complexes to Rewire Kinase Signaling in Hepatocellular Carcinoma

(2025)10.1158/0008-5472.28431537

N/A

0DataRank · unranked

0 citations

Adriana Pitea, Gwendolyn M. Jang, Zhong Xu, Huat Chye Lim, Alex L. Choi +22 more

Unbiased Proteomic Profiling Uncovers a Targetable GNAS/PKA/PP2A Axis in Small Cell Lung Cancer Stem Cells

Cancer Cell(2020)10.1016/j.ccell.2020.05.003

N/A

0DataRank · unranked

86 citations

Sandra Cristea, James T. Webber, Rebecca S. Levin, Steven M. Moss, Andy He +23 more

Brain-Restricted mTOR Inhibition with Binary Pharmacology

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.10.12.336677

N/A

0DataRank · unranked

10 citations

Qi-Wen Fan, Xujun Luo, Kevin Lou, William A. Weiss, Kevan M. Shokat +1 more

State-selective Modulation of Heterotrimeric Gαs Signaling with Macrocyclic Peptides

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.25.054080

N/A

0DataRank · unranked

5 citations

Qi Hu, Rong Gao, Hayden Peacock, Emily E. Blythe, Ziyang Zhang +4 more

Brain-Specific Inhibition of mTORC1 by a Dual Drug Strategy: A Novel Approach for the Treatment of Alcohol Use Disorder

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.10.12.336701

N/A

0DataRank · unranked

2 citations

Ziyang Zhang, Khanhky Phamluong, Drishti Soneja, Kevan M. Shokat, Dorit Ron +1 more

Brain-Restricted mTOR Inhibition with Binary Pharmacology

Research Square(2020)10.21203/rs.3.rs-92256/v1

N/A

0DataRank · unranked

2 citations

Ziyang Zhang, Qi-Wen Fan, Xujun Luo, Kevin Lou, William A. Weiss +1 more

KRAS is vulnerable to reversible switch-II pocket engagement in cells

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.15.464544

N/A

0DataRank · unranked

9 citations

D. Matthew Peacock, Qinheng Zheng, Joel A. Walker, Ziyang Zhang, Chad Zimprich +7 more

Evolutionarily divergent mTOR remodels the translatome to drive rapid wound closure and regeneration

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.28.465024

N/A

0DataRank · unranked

3 citations

Hannah D. Rosenblatt, Leila Shokat, Shizhong Dai, Duygu Kuzuoğlu‐Öztürk, Zijian Zhang +4 more

Chemical acylation of an acquired serine suppresses oncogenic signaling of K-Ras(G12S)

Nature Chemical Biology(2022)10.1038/s41589-022-01065-9

N/A

0DataRank · unranked

149 citations

Keelan Z. Guiley, Kevan M. Shokat, Ziyang Zhang