Transcriptome data of temporal and cingulate cortex in the Rett syndrome brain is a dataset published in Scientific Data (2020). On theSindex it has a DataRank of 0.505, placing it in the top 38.1% of the data-sharing corpus. It has been cited 17 times, with 11 citing works in its 1-hop citation network. Its calibrated FAIR score is 65/100.
Ranks in the top 38% for downstream scientific impact
Linked data & code
DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?
FAIR checklist signals are shown for context only and do not affect DataRank scoring.
Full FAIR picture · advisory
The headline score is computed from the scored criteria — the fact-shaped checks (a repository, an accession, a licence) that two independent models agree on. The advisory criteria below are real FAIR guidance but rest on judgment calls that models read differently, so they inform without moving the number.
“Count matrix and normalized count matrix were submitted to the NCBI Gene Expression Omnibus (GEO) under accession number GSE12838024.”
The paper provides a GEO accession (GSE128380) and an SRA accession (SRP188555), both persistent identifiers. [majority verdict 'yes' (3/5 passes agreed)]
RDA-F1-01D — FAIR Data Maturity Model: 'Data is identified by a persistent identifier' (priorit · RDA-F1-02D — FAIR Data Maturity Model: 'Data is identified by a globally unique identifier' · FsF-F1-02D — F-UJI/FAIRsFAIR: 'Data is assigned a persistent identifier'
“Count matrix and normalized count matrix were submitted to the NCBI Gene Expression Omnibus (GEO) under accession number GSE12838024.”
The paper names the NCBI Gene Expression Omnibus (GEO) as the repository. [majority verdict 'yes' (4/5 passes agreed)]
RDA-F4-01M — FAIR Data Maturity Model: metadata is offered so it can be harvested and indexed ( · NIH DMS Policy Element 4 (NOT-OD-21-014) — name the repository where data will be archived · NSTC Desirable Characteristics of Data Repositories (2022) — 'Long-Term Sustainability', 'Reten
“24. Aldinger, K. A. Transcriptome data of temporal and cingulate cortex in the Rett syndrome brain. Gene Expression Omnibus https://identifiers.org/geo:GSE128380 (2019).”— not found in the paper; verdict downgraded
The dataset appears as a reference list entry (reference 24). [downgraded to 'partial' — no verifiable quote from the paper] [majority verdict 'partial' (4/5 passes agreed)]
FORCE11 Joint Declaration of Data Citation Principles (2014) — data should be cited as a first- · RDA-F3-01M — metadata clearly and explicitly includes the identifier of the data it describes · FsF-F3-01M — F-UJI: 'Metadata includes the identifier of the data it describes'
Advisory · not in the published score
“Count matrix and normalized count matrix were submitted to the NCBI Gene Expression Omnibus (GEO) under accession number GSE12838024. The raw FASTQ files can be downloaded from the Sequence Read Archive (SRA) under accession number SRP18855525.”
The Data Records section points to repository records with accessions. [majority verdict 'yes' (3/5 passes agreed)]
Colavizza, Hrynaszkiewicz, Staden, Whitaker & McGillivray (2020), 'The citation advantage of li · Springer Nature research data policy — Data Availability Statements: standard statement templat · RDA-F3-01M — metadata clearly and explicitly includes the identifier of the data it describes
“Table 2. RNA Sample Characteristics.”
The paper includes Table 2, an itemised inventory of the samples.
RDA-F2-01M — 'Rich metadata is provided to allow discovery' (priority Essential) · FsF-F2-01M — F-UJI: 'Metadata includes descriptive core elements to support data findability' · FsF-R1-01MD — F-UJI: 'Metadata specifies the content of the data'
“Count matrix and normalized count matrix were submitted to the NCBI Gene Expression Omnibus (GEO) under accession number GSE12838024. The raw FASTQ files can be downloaded from the Sequence Read Archive (SRA) under accession number SRP18855525.”
The paper states the data are deposited in public repositories with no precondition. [majority verdict 'yes' (3/5 passes agreed)]
RDA-A1.1-01D — 'Data is accessible through a free access protocol' · FsF-A1-01M — F-UJI: 'Metadata contains access level and access conditions of the data' · NSTC Desirable Characteristics of Data Repositories (2022) — 'Free and Easy Access'
Advisory · not in the published score
“The raw FASTQ files can be downloaded from the Sequence Read Archive (SRA) under accession number SRP18855525.”
The paper does not use an explicit access-level label but describes the action of downloading from repositories. [majority verdict 'partial' (3/5 passes agreed)]
FsF-A1-01M — F-UJI: 'Metadata contains access level and access conditions of the data' · RDA-A1-01M — metadata contains information to enable the user to get access to the data · COAR Controlled Vocabularies — Access Rights v1.0 (open / embargoed / restricted / metadata-onl
“The raw FASTQ files can be downloaded from the Sequence Read Archive (SRA) under accession number SRP18855525.”
The data are deposited in public repositories with no gatekeeper named.
NIH Genomic Data Sharing Policy (NOT-OD-14-124) — controlled-access via a Data Access Committee · RDA-A1.2-01D — 'Data is accessible through an access protocol that supports authentication and · NIH DMS Policy Element 5 (NOT-OD-21-014) — Access, Distribution, or Reuse Considerations (conse
The paper does not state any timeframe for data availability or persistence commitment. [majority verdict 'no' (4/5 passes agreed)]
NIH DMS Plan Element 4 (NOT-OD-21-014) — Data Preservation, Access, and Associated Timelines · NSTC Desirable Characteristics (2022), Organizational Infrastructure: 'Retention Policy' · RDA-A2-01M — 'Metadata is guaranteed to remain available after data is no longer available'
“The raw FASTQ files can be downloaded from the Sequence Read Archive (SRA) under accession number SRP18855525.”
FASTQ is an open, community-standard format, and the paper states that raw FASTQ files are available. [majority verdict 'yes' (3/5 passes agreed)]
FsF-R1.3-02D — F-UJI: 'Data is available in a file format recommended by the target research co · RDA-R1.3-02D — data is expressed in a machine-understandable community standard · RDA-I1-01D — data uses a knowledge representation expressed in a standardised format
Advisory · not in the published score
The paper does not name a data or metadata community standard or manuscript reporting guideline.
RDA-R1.3-01M — 'Metadata complies with a community standard' (priority Essential) · RDA-R1.3-01D — 'Data complies with a community standard' · RDA-I2-01M — '(Meta)data use vocabularies that follow FAIR principles'
“The first dataset examined pooled frontal and temporal cortex (FTTX) for each of three individuals with RTT compared to three CTL and is available from the Sequence Read Archive under accession number PRJNA30268529.”
The paper provides SRA accession numbers for external datasets used in the meta-analysis. [majority verdict 'yes' (4/5 passes agreed)]
RDA-I3-01M — '(meta)data include references to other (meta)data' · RDA-I3-03M — 'metadata includes qualified references to other metadata' · FsF-I3-01M — F-UJI: 'Metadata includes links between the data and its related entities'
The paper does not name a license or reuse terms for the data.
RDA-R1.1-01M — 'Metadata includes information about the licence under which the data can be reu · RDA-R1.1-02M — 'Metadata refers to a standard reuse licence' · RDA-R1.1-03M — 'Metadata refers to a machine-understandable reuse licence'
The paper does not provide a version token or date for the data snapshot.
DataCite Metadata Schema 4.6 — the 'Version' property · RDA-R1.2-01M — provenance information (which version was used is provenance) · NSTC Desirable Characteristics of Data Repositories (2022) — 'Provenance', 'Retention Policy'
The paper only lists third-party software URLs and does not provide a locator for its own code.
NIH DMS Policy Element 2 (NOT-OD-21-014) — 'Related Tools, Software and/or Code' · FAIR4RS Principles v1.0 (Chue Hong et al., 2022; RDA/FORCE11/ReSA) — FAIR Principles for Resear · FORCE11 Software Citation Principles (Smith, Katz & Niemeyer, 2016, PeerJ CS 2:e86)
“This work was supported by NIH grant MH067842 to P.L. and an Epilepsy Foundation of Greater Los Angeles fellowship to K.A.A.”— not found in the paper; verdict downgraded
The paper provides the NIH grant number MH067842. [downgraded to 'partial' — no verifiable quote from the paper] [majority verdict 'partial' (4/5 passes agreed)]
DataCite Metadata Schema 4.6 — 'FundingReference' property (funderName, funderIdentifier, award · Crossref Funder Registry — canonical funder identifiers for funding metadata · RDA-F2-01M — rich metadata provided to allow discovery (funding is part of the descriptive reco
Advisory · not in the published score
“Libraries were pooled and sequenced in two lanes using an Illumina HiSeq 2000 sequencer.”
The paper names the sequencing platform and specific software versions used.
RDA-R1.2-01M — 'Metadata includes provenance information according to community- specific standa · FsF-R1.2-01M — F-UJI: 'Metadata includes provenance information about data creation or generati · W3C PROV-O (W3C Recommendation, 2013) — the entity/activity/agent model of provenance
“Data Records”
The paper describes the data within the article (e.g., the 'Data Records' section and tables) but does not mention a separate documentation file that accompanies the data deposit. [majority verdict 'partial' (3/5 passes agreed)]
RDA-R1-01M — '(Meta)data are richly described with a plurality of accurate and relevant attribu · FsF-R1-01MD — F-UJI: 'Metadata specifies the content of the data' · NIH DMS Policy Element 3 (NOT-OD-21-014) — Standards (documentation and metadata to accompany t
Calibrated FAIR score — a parallel quality metric, independent of the DataRank citation score. See the full evaluation →
Base Score Contribution
0.434
From this paper's citation signal
Citation Network Contribution
0.0714
From 5 citing papers with measurable signal
Ranked by each citer's contribution to N(p) — log1p(Cq) divided by its reference count — out of 11 citers.
Epilepsy Foundation
Grant: 188603
U.S. Department of Health & Human Services | NIH | National Institute of Mental Health
Grant: MH067842
NIMH NIH HHS
Grant: R01 MH067842
NIMH NIH HHS
Grant: R56 MH067842
National Institutes of Health
Grant: 5R01MH067842-10
Function and Structure Adaptations in Forebrain Development
Fields of Study
MeSH Terms
Keywords
Metadata record for: Transcriptome data of temporal and cingulate cortex in the Rett syndrome brain
Metadata record for: Transcriptome data of temporal and cingulate cortex in the Rett syndrome brain