James W. MacDonald

Also affiliated with University of Washington, University of Washington Applied Physics Laboratory

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 2%percentile

2.4Author DataRank

Indexed papers

5in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 5 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Genome-wide analyses characterize shared heritability among cancers and identify novel cancer susceptibility regions

JNCI Journal of the National Cancer Institute(2023)10.1093/jnci/djad043

Top 25%

0.804DataRank

Top 25%33 citations

Lu Wang, Helian Feng, Arunabha Majumdar, Sijia Huo, James W. MacDonald +56 more

Papers

Driven by 49 papers — median percentile 61. Top paper: “Genome-wide analyses characterize shared heritability among cancers and identify novel cancer susceptibility regions”.

Genome-wide analyses characterize shared heritability among cancers and identify novel cancer susceptibility regions

JNCI Journal of the National Cancer Institute(2023)10.1093/jnci/djad043

Top 25%

0.804DataRank

Top 25%33 citations

Lu Wang, Helian Feng, Arunabha Majumdar, Sijia Huo, James W. MacDonald +56 more

Transcriptome data of temporal and cingulate cortex in the Rett syndrome brain

Scientific Data(2020)10.1038/s41597-020-0527-2

Top 38%

0.505DataRank

Top 38%17 citations

Andrew E. Timms, James W. MacDonald, Hanna K. McNamara, Jennifer Herstein, Theo K. Bammler +4 more

A genome scale transcriptional regulatory model of the human placenta

Science Advances(2024)10.1126/sciadv.adf3411

Top 39%

0.489DataRank

Top 39%18 citations

Kylia Ahuna, Yeon Mi Hwang, Jocelynn R. Pearl, Hanna Liao, Paul Shannon +21 more

A transcriptomic comparison of in vitro models of the human placenta

Placenta(2024)10.1016/j.placenta.2024.11.007

Top 41%

0.467DataRank

Top 41%13 citations

S.K. Nair, Evan J. Firsick, James W. MacDonald, Ciara Thoreson, James A. Litch +8 more

A Genome Scale Transcriptional Regulatory Model of the Human Placenta

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.09.27.509541

Top 70%

0.165DataRank

Top 70%2 citations

Kylia Ahuna, Yeon Mi Hwang, Jocelynn R. Pearl, Hanna Liao, Paul Shannon +21 more

Associations between maternal plasma concentrations of corticotrophin releasing hormone and the placental transcriptome

Placenta(2024)10.1016/j.placenta.2024.12.021

N/A

0.104DataRank · unranked

1 citations

Mariana Parenti, Samantha Lapehn, Chaini Konwar, Leena Kadam, Evan J. Firsick +17 more

Placental transcriptomic signatures of spontaneous preterm birth

American Journal of Obstetrics and Gynecology(2022)10.1016/j.ajog.2022.07.015

N/A

0DataRank · unranked

58 citations

James W. MacDonald, Theo K. Bammler, Drew B. Day, Christine T. Loftus, Erin Buth +9 more

Prenatal exposure to particulate matter and placental gene expression

Environment International(2022)10.1016/j.envint.2022.107310

N/A

0DataRank · unranked

41 citations

James W. MacDonald, Michael Hussey, Theo K. Bammler, Christine T. Loftus, Alison G. Paquette +10 more

Prolonged, Low-Level Exposure to the Marine Toxin, Domoic Acid, and Measures of Neurotoxicity in Nonhuman Primates

Environmental Health Perspectives(2022)10.1289/ehp10923

N/A

0DataRank · unranked

19 citations

Christopher Williams, Jian‐Liang Li, James W. MacDonald, Theo K. Bammler, Todd L. Richards +11 more

Symptomatic and asymptomatic domoic acid exposure in zebrafish (Danio rerio) revealed distinct non-overlapping gene expression patterns in the brain

Aquatic Toxicology(2022)10.1016/j.aquatox.2022.106310

N/A

0DataRank · unranked

4 citations

Kathi A. Lefebvre, James W. MacDonald, Theo K. Bammler, Neelakanteswar Aluru, Alia S. Hidayat

An optimized proteomics-based approach to estimate blood contamination and cellular heterogeneity of frozen placental tissue

Placenta(2022)10.1016/j.placenta.2022.12.007

N/A

0DataRank · unranked

4 citations

Guihua Yue, Alison G. Paquette, Sheela Sathyanarayana, Daniel A. Enquobahrie, Theo K. Bammler +4 more

Placental transcriptomic signatures of prenatal exposure to Hydroxy-Polycyclic aromatic hydrocarbons

Environment International(2023)10.1016/j.envint.2023.107763

N/A

0DataRank · unranked

36 citations

Samantha Lapehn, Sophia L Freije, James W. MacDonald, Theo K. Bammler, Drew B. Day +9 more

Mono(2-ethylhexyl) phthalate induces transcriptomic changes in placental cells based on concentration, fetal sex, and trophoblast cell type

Archives of Toxicology(2023)10.1007/s00204-023-03444-0

N/A

0DataRank · unranked

21 citations

Scott Houghtaling, Kylia Ahuna, Leena Kadam, James W. MacDonald, Theo K. Bammler +5 more

Characterization of Xenobiotic and Steroid Disposition Potential of Human Placental Tissue and Cell Lines (BeWo, JEG-3, JAR, and HTR-8/SVneo) by Quantitative Proteomics

Drug Metabolism and Disposition(2023)10.1124/dmd.123.001345

N/A

0DataRank · unranked

11 citations

Samantha Lapehn, Alison G. Paquette, Dilip Kumar Singh, James W. MacDonald, Theo K. Bammler +6 more

Identification of prognostic biomarkers for antibiotic associated nephrotoxicity in cystic fibrosis

Journal of Cystic Fibrosis(2023)10.1016/j.jcf.2023.10.021

N/A

0DataRank · unranked

4 citations

Francine Cesar, Leila R. Zelnick, Nicholas G. O’Connor, Zoie A. Bailey, J.L. Lo +11 more

Associations of prenatal exposure to NO2 and near roadway residence with placental gene expression

Placenta(2023)10.1016/j.placenta.2023.05.004

N/A

0DataRank · unranked

2 citations

Daniel A. Enquobahrie, Christine T. Loftus, James W. MacDonald, Theo K. Bammler, Alison G. Paquette +10 more

Glucocerebrosidase deficiency leads to neuropathology via cellular immune activation

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.13.571406

N/A

0DataRank · unranked

1 citations

Ruth E. Thomas, Gillian Milstein, Gautam Pareek, Theo K. Bammler, James W. MacDonald +2 more

Mouse sarcopenia model reveals sex- and age-specific differences in phenotypic and molecular characteristics

Journal of Clinical Investigation(2024)10.1172/jci172890

N/A

0DataRank · unranked

45 citations

Kora Krumm, Bárbara Anderson, Anthony Christiani, Lena Strait, Theresa Li +12 more

Challenges and Opportunities for the Clinical Translation of Spatial Transcriptomics Technologies

Glomerular Diseases(2024)10.1159/000538344

N/A

0DataRank · unranked

44 citations

David K. Prince, James W. MacDonald, Theo K. Bammler, Shreeram Akilesh, Kelly D. Smith

Placental transcriptomic signatures of prenatal and preconceptional maternal stress

Molecular Psychiatry(2024)10.1038/s41380-023-02403-6

N/A

0DataRank · unranked

19 citations

Sophia L Freije, James W. MacDonald, Theo K. Bammler, Ciara Benson, Kecia N. Carroll +8 more

Human enteroid monolayers: A novel, functionally stable model for investigating oral drug disposition

Drug Metabolism and Disposition(2024)10.1124/dmd.124.001551

N/A

0DataRank · unranked

13 citations

Eimear T O'Mahony, James W. MacDonald, Theo K. Bammler, Mark Donowitz, Edward J. Kelly +2 more

Associations Between Prenatal Vitamin D and Placental Gene Expression

Journal of Nutrition(2024)10.1016/j.tjnut.2024.10.019

N/A

0DataRank · unranked

9 citations

Melissa M. Melough, Samantha Lapehn, James W. MacDonald, Theo K. Bammler, Evan J. Firsick +10 more

Cystic fibrosis-related diabetes is associated with reduced islet protein expression of GLP-1 receptor and perturbation of cell-specific transcriptional programs

Scientific Reports(2024)10.1038/s41598-024-76722-1

N/A

0DataRank · unranked

8 citations

Rachna Vemireddy, Joseph Castillo, Brendy S Fountaine, Theo K. Bammler, James W. MacDonald +3 more

Glucocerebrosidase deficiency leads to neuropathology via cellular immune activation

PLoS Genetics(2024)10.1371/journal.pgen.1011105

N/A

0DataRank · unranked

6 citations

Ruth E. Thomas, Gillian Milstein, Gautam Pareek, Theo K. Bammler, James W. MacDonald +2 more

Sex-specific associations between placental corticotropin releasing hormone and problem behaviors in childhood

Psychoneuroendocrinology(2024)10.1016/j.psyneuen.2024.106994

N/A

0DataRank · unranked

3 citations

Alexandra D. W. Sullivan, Tomomi Workman, Yuhong Zhang, Christine T. Loftus, Adam A. Szpiro +14 more

RNAseqCovarImpute: a multiple imputation procedure that outperforms complete case and single imputation differential expression analysis

Genome biology(2024)10.1186/s13059-024-03376-7

N/A

0DataRank · unranked

2 citations

Sheela Sathyanarayana, Adam A. Szpiro, James W. MacDonald, Alison G. Paquette, Brennan H. Baker

Transcriptomic comparison of in vitro models of the human placenta

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.06.14.598695

N/A

0DataRank · unranked

2 citations

S.K. Nair, Evan J. Firsick, James W. MacDonald, Ciara Thoreson, James A. Litch +8 more

Associations Between Prenatal Vitamin D and Placental Gene Expression

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.05.10.593571

N/A

0DataRank · unranked

1 citations

Melissa M. Melough, Samantha Lapehn, James W. MacDonald, Theo K. Bammler, Evan J. Firsick +10 more

Mitochondrial Calcium Signaling Regulates Branched-Chain Amino Acid Catabolism in Fibrolamellar Carcinoma

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.05.27.596106

N/A

0DataRank · unranked

1 citations

Melissa J. S. MacEwen, Jane Chea, Heidi L. Kenerson, Albert A. Kwong, Timothy M. Locke +13 more

Associations of maternal blood biomarkers of prenatal APAP exposure with placental gene expression and child attention deficit hyperactivity disorder

Nature Mental Health(2025)10.1038/s44220-025-00387-6

N/A

0DataRank · unranked

9 citations

Theo K. Bammler, Emily S. Barrett, Nicole R. Bush, Brent R. Collett, Karen J. Derefinko +11 more

An assessment of organophosphate ester mixtures and the placental transcriptome

Environment International(2025)10.1016/j.envint.2025.109402

N/A

0DataRank · unranked

7 citations

Mariana Parenti, Evan J. Firsick, Dennis Khodasevich, Brennan H. Baker, Drew B. Day +14 more

Mitochondrial calcium signaling regulates branched-chain amino acid catabolism in fibrolamellar carcinoma

Science Advances(2025)10.1126/sciadv.adu9512

N/A

0DataRank · unranked

6 citations

Melissa J. S. MacEwen, Jane Chea, Heidi L. Kenerson, Albert A. Kwong, Timothy M. Locke +13 more

Rigor and Reproducibility of Spatial Transcriptomics Performed on Clinically Sourced Human Tissues

Laboratory Investigation(2025)10.1016/j.labinv.2025.104190

N/A

0DataRank · unranked

4 citations

James W. MacDonald, Xianwu Li, Emily Beirne, Galen Stewart, Theo K. Bammler +2 more

Associations of placental lncRNA expression with maternal pre-pregnancy BMI and infant birthweight in two birth cohorts

Journal of Developmental Origins of Health and Disease(2025)10.1017/s204017442500011x

N/A

0DataRank · unranked

1 citations

James W. MacDonald, Theo K. Bammler, Fasil Tekola‐Ayele, Kathleen F. Kerr, Alison G. Paquette +7 more

A Flexible and Responsive Remote Study Design to Assess Gene Expression Changes During Wildfire Smoke Exposure with homeRNA, an At-home Blood Sampling Kit

medRxiv(2025)10.1101/2025.10.11.25337783

N/A

0DataRank · unranked

4 citations

Lauren G. Brown, Yuting Zeng, Taushif Khan, Ingrid H Robertson, Dakota S. Kennedy +16 more

Butyrate rescues chlorpyrifos-induced social deficits through inhibition of class I histone deacetylases

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.10.19.683261

N/A

0DataRank · unranked

3 citations

Ally Xinyi Kong, Ping Zhang, Jinhua Chi, Khoa Pham, M. S. Johnson +9 more

Placental Gene Expression Associated With Early Childhood Growth Trajectories and Obesity Risk

Obesity(2025)10.1002/oby.70000

N/A

0DataRank · unranked

0 citations

Luhang Han, Alison G. Paquette, James W. MacDonald, Theo K. Bammler, Christine T. Loftus +7 more

The Placental Transcriptome Serves as a Mechanistic Link between Prenatal Phthalate Exposure and Placental Efficiency

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.08.05.664214

N/A

0DataRank · unranked

0 citations

Samantha Lapehn, James W. MacDonald, Theo K. Bammler, Adam A. Szpiro, Marnie F. Hazlehurst +9 more

Evaluation of toxicological mechanisms of ochratoxin-A in human primary proximal tubule epithelial cells

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.08.29.673189

N/A

0DataRank · unranked

0 citations

Theo K. Bammler, James W. MacDonald, Angela Zheng, Catherine K. Yeung, Jonathan Himmelfarb +2 more

From Home to Transcriptome: Comparing the transcriptomic profile of induced immune response via lipopolysaccharide stimulation in homeRNA and venous blood

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.09.27.678977

N/A

0DataRank · unranked

0 citations

Xiaofu Wei, Laura A. Milton, M Yunos Alizai, James W. MacDonald, Theo K. Bammler +9 more

Pervasive food contaminant ochratoxin‐A induces energy crisis: Mitochondrial dysfunction in human primary proximal tubule cells

Toxicology Reports(2025)10.1016/j.toxrep.2025.102169

N/A

0DataRank · unranked

0 citations

Theo K. Bammler, James W. MacDonald, Angela Zheng, Catherine K. Yeung, Jonathan Himmelfarb +2 more

The placental transcriptome serves as a mechanistic link between prenatal phthalate exposure and placental efficiency

Environment International(2025)10.1016/j.envint.2025.109949

N/A

0DataRank · unranked

0 citations

Samantha Lapehn, James W. MacDonald, Theo K. Bammler, Adam A. Szpiro, Marnie F. Hazlehurst +9 more

Short Report: Circulating microRNAs are associated with incident diabetes over 10 years in Japanese Americans

Scientific Reports(2020)10.1038/s41598-020-63606-3

N/A

0DataRank · unranked

14 citations

Daniel A. Enquobahrie, Theo K. Bammler, Sengkeo Srinouanprachanh, James W. MacDonald, Steven E. Kahn +4 more

Placental proteomic signatures of preterm birth, gestational age, and birthweight

BMC Pregnancy and Childbirth(2025)10.1186/s12884-025-08558-0

N/A

0DataRank · unranked

0 citations

Laken Kruger, Bhagwat Prasad, James W. MacDonald, Theo K. Bammler, Chaini Konwar +7 more

A Comprehensive Assessment of Associations between Prenatal Phthalate Exposure and the Placental Transcriptomic Landscape

Environmental Health Perspectives(2021)10.1289/ehp8973

N/A

0DataRank · unranked

50 citations

James W. MacDonald, Samantha Lapehn, Theo K. Bammler, Laken Kruger, Drew B. Day +13 more

Spiny mice activate unique transcriptional programs after severe kidney injury regenerating organ function without fibrosis

iScience(2021)10.1016/j.isci.2021.103269

N/A

0DataRank · unranked

50 citations

Chris M. Brewer, Paul Wakenight, Nadia M. Bahrami, Kristina G. Bernardi, Amy Tran +14 more

Neonatal Exposure to BPA, BDE-99, and PCB Produces Persistent Changes in Hepatic Transcriptome Associated With Gut Dysbiosis in Adult Mouse Livers

Toxicological Sciences(2021)10.1093/toxsci/kfab104

N/A

0DataRank · unranked

23 citations

Moumita Dutta, Joseph L. Dempsey, Hans‐Joachim Lehmler, James W. MacDonald, Theo K. Bammler +6 more

Persistence of improved glucose homeostasis in Gclm null mice with age and cadmium treatment

Redox Biology(2021)10.1016/j.redox.2021.102213

N/A

0DataRank · unranked

17 citations

Dianne Botta, Collin C. White, David Scoville, Sengkeo Srinouanprachanh, Theo K. Bammler +3 more

Whole genome methylation and transcriptome analyses to identify risk for cerebral palsy (CP) in extremely low gestational age neonates (ELGAN)

Scientific Reports(2021)10.1038/s41598-021-84214-9

N/A

0DataRank · unranked

15 citations

Theo K. Bammler, James W. MacDonald, Krystle Perez, Bryan A. Comstock, Sandra E. Juul +1 more

James W. MacDonald

Indexed papers

Top data-sharing exemplar

Papers