Monte Carlo Simulations of Nucleosome Chains to Identify Factors that Control DNA Compaction and Access is a research paper published in Innovations in Biomolecular Modeling and Simulations (2012). On theSindex it has a DataRank of 0.360. It has been cited 6 times, with 2 citing works in its 1-hop citation network.
Despite extensive research over the last three decades, the spatial organization of the nucleosome chain in chromatin is still only partially understood, although the nucleosome structure as its basic building block is known at atomic resolution. Here, we discuss the application of Monte Carlo simulations to investigate the conformational flexibility of the nucleosome chain in a systematic manner. Its folding into compacted structures provides an additional layer for regulating access to the DNA sequence information. The contributions of nucleosome positioning, local nucleosome geometry, nucleosome-nucleosome and histone octamer-DNA interactions into MC models are considered. It is discussed how relatively minor local variations of the nucleosome structure can translate into large changes of the overall conformation of the nucleosome chain.
FAIR checklist signals are shown for context only and do not affect DataRank scoring.
Base Score Contribution
0.292
From this paper's citation signal
Citation Network Contribution
0.0681
From 2 citing papers with measurable signal
Ranked by citation count — the same ordering the engine uses when summing log1p(Cq) over citers.
DataRank blends this paper's own citation count with the influence of the papers that cite it. Here, roughly 81% comes from its base citations and 19% from the citation network (2 citing papers contributed measurable signal).
Citers are pulled from OpenAlex sorted by cited_by_count:descand capped per paper, so when the cap binds we keep the highest-signal references and the score is reproducible across reruns.
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