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CUX1 and IκBζ (NFKBIZ) mediate the synergistic inflammatory response to TNF and IL-17A in stromal fibroblasts

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.1912702117Source: DataRank Database

CUX1 and IκBζ (NFKBIZ) mediate the synergistic inflammatory response to TNF and IL-17A in stromal fibroblasts is a research paper published in Proceedings of the National Academy of Sciences (2020). On theSindex it has a DataRank of 2.8. It has been cited 95 times, with 83 citing works in its 1-hop citation network.

N/A

2.8DataRank · unranked

Scored on demand from live citation data

Open Access95 citations · 83 citing works in its network

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (11 grants)Impact (FWCI 4.02)OA: greenTopics (63)Linked Datasets (20)DataCite Reuse (20)IDs (PubMed, OpenAlex)SDGs (3)

FAIR Checklist

Context only (not used in score)

Findable (2/2)

Has DOI
Indexed in repositories

Accessible (1/2)

Open Access

Interoperable (2/2)

DataCite relations
Linked datasets

Reusable (0/3)

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DataRank Breakdown

Base Score 24%Citation Network 76%

Base Score Contribution

0.685

From this paper's citation signal

Citation Network Contribution

2.2

From 64 citing papers with measurable signal

Learn more about DataRank methodology →

Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 83 citers.

Periplocin inhibits hepatocellular carcinoma progression and reduces the recruitment of MDSCs through AKT/NF-κB pathway
Life Sciences202326 citations27 referencesContributes 0.122
Drivers of heterogeneity in synovial fibroblasts in rheumatoid arthritis
Nature Immunology2023180 citations64 referencesContributes 0.081
Sensing plasma membrane pore formation induces chemokine production in survivors of regulated necrosis
Developmental Cell202254 citations50 referencesContributes 0.080
Membrane Fusion‐Mediated Loading of Therapeutic siRNA into Exosome for Tissue‐Specific Application
Advanced Materials202487 citations56 referencesContributes 0.080
Ginkgo biloba Extract GBE50 ameliorates cerebrovascular dysfunction and cognitive impairment in a mouse model of Alzheimer's disease
Phytomedicine202514 citations34 referencesContributes 0.080

Authors (9)

Hung N. Nguyen ORCID,Erika H. Noss ORCID,Daimon P. Simmons ORCID,Fumitaka Mizoguchi ORCID,Gerald F. Watts ORCID

Live enrichment

PubMed:32079724 OpenAlex:https://openalex.org/W3007823876

HHS | National Institutes of Health

Grant: U01GM092691

HHS | National Institutes of Health

Grant: R01AR063709

HHS | National Institutes of Health

Grant: F31AR070582

HHS | National Institutes of Health

Grant: T32HL007627

national institutes of health

Grant: RO1AR073833

National Institutes of Health

Grant: 5U19AI111224-05

Metabolic factors that control the spectrum of human tuberculosis

National Institutes of Health

Grant: 5T32HL007627-27

Vascular, Pulmonary and Renal Injury

National Institutes of Health

Grant: 5R01AR063709-09

Expanded fibroblast subset drives pathology in rheumatoid arthritis

National Institutes of Health

Grant: 5F31AR070582-02

Transcriptomics in synoviocytes defines pathogenesis of rheumatoid arthritis

National Institutes of Health

Grant: 1UH2AR067677-01

RA-SLE Molecular Deconstruction Leadership Center

National Institutes of Health

Grant: 1U01GM092691-01

Genetic predictors of response to anti-TNF therapy in rheumatoid arthritis

FWCI

4.02

Citation Percentile

1.0%

Citation Trend

2020

2021

2022

2023

2024

2025

2026

greenLicense: https://www.pnas.org/site/aboutpnas/licenses.xhtml

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7071902

publisherhttp://www.pnas.org/syndication/doi/10.1073/pnas.1912702117

publisherhttps://pnas.org/doi/pdf/10.1073/pnas.1912702117

journalhttps://doi.org/10.1073/pnas.1912702117

Fields of Study

NF-κB Signaling PathwaysImmune Response and InflammationCytokine Signaling Pathways and Interactions0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

Arthritis, RheumatoidCells, CulturedChemotactic FactorsFibroblastsHumansInflammationMonocytesRepressor ProteinsSynovial FluidTranscription FactorsTumor Necrosis Factor-alphaInterleukin-6Stromal CellsHomeodomain ProteinsMatrix Metalloproteinase 3Chemokines, CXCInterleukin-17RNA, Small InterferingAdaptor Proteins, Signal TransducingTranscription Factor RelAChemokine CXCL1Chemokine CXCL2Transcriptome

Keywords

CXCL1CXCL2Tumor necrosis factor alphaTranscription factorCell biologyCytokineInflammationGene silencingBiologyCancer researchChemokineImmunologyChemistryGeneGeneticsHomeodomain ProteinsChemotactic FactorsInterleukin-6Chemokine CXCL1Chemokine CXCL2Interleukin-17Transcription Factor RelAFibroblastsMonocytesArthritis, RheumatoidRepressor ProteinsSynovial FluidHumansMatrix Metalloproteinase 3RNA, Small InterferingStromal CellsChemokines, CXCCells, CulturedAdaptor Proteins, Signal Transducing

Sustainable Development Goals

SDG 2: 2. Zero hungerSDG 3: 3. Good healthSDG 0: Good health and well-being

Additional file 3 of Identification of monocyte-associated genes as predictive biomarkers of heart failure after acute myocardial infarction

10.6084/m9.figshare.13843522.v1figshare

Additional file 3 of Identification of monocyte-associated genes as predictive biomarkers of heart failure after acute myocardial infarction

10.6084/m9.figshare.13843522figshare

Additional file 4 of Identification of monocyte-associated genes as predictive biomarkers of heart failure after acute myocardial infarction

10.6084/m9.figshare.13843525.v1figshare

Additional file 4 of Identification of monocyte-associated genes as predictive biomarkers of heart failure after acute myocardial infarction

10.6084/m9.figshare.13843525figshare

Additional file 1 of CUX1 attenuates the apoptosis of renal tubular epithelial cells induced by contrast media through activating the PI3K/AKT signaling pathway

10.6084/m9.figshare.25996953.v1figshare

Additional file 1 of CUX1 attenuates the apoptosis of renal tubular epithelial cells induced by contrast media through activating the PI3K/AKT signaling pathway

10.6084/m9.figshare.25996953figshare

Additional file 8 of Identification of monocyte-associated genes as predictive biomarkers of heart failure after acute myocardial infarction

10.6084/m9.figshare.13843540figshare

Additional file 5 of Identification of monocyte-associated genes as predictive biomarkers of heart failure after acute myocardial infarction

10.6084/m9.figshare.13843531figshare

Additional file 2 of Identification of monocyte-associated genes as predictive biomarkers of heart failure after acute myocardial infarction

10.6084/m9.figshare.13843519figshare

Additional file 1 of Identification of monocyte-associated genes as predictive biomarkers of heart failure after acute myocardial infarction

10.6084/m9.figshare.13843516.v1figshare

Additional file 8 of Identification of monocyte-associated genes as predictive biomarkers of heart failure after acute myocardial infarction

10.6084/m9.figshare.13843540.v1figshare

Additional file 6 of Identification of monocyte-associated genes as predictive biomarkers of heart failure after acute myocardial infarction

10.6084/m9.figshare.13843534.v1figshare

Additional file 6 of Identification of monocyte-associated genes as predictive biomarkers of heart failure after acute myocardial infarction

10.6084/m9.figshare.13843534figshare

Additional file 7 of Identification of monocyte-associated genes as predictive biomarkers of heart failure after acute myocardial infarction

10.6084/m9.figshare.13843537.v1figshare

Additional file 7 of Identification of monocyte-associated genes as predictive biomarkers of heart failure after acute myocardial infarction

10.6084/m9.figshare.13843537figshare

Additional file 1 of Identification of monocyte-associated genes as predictive biomarkers of heart failure after acute myocardial infarction

10.6084/m9.figshare.13843516figshare

Additional file 2 of Identification of monocyte-associated genes as predictive biomarkers of heart failure after acute myocardial infarction

10.6084/m9.figshare.13843519.v1figshare

Additional file 5 of Identification of monocyte-associated genes as predictive biomarkers of heart failure after acute myocardial infarction

10.6084/m9.figshare.13843531.v1figshare

slowkow/fibrotime: First release

10.5281/zenodo.3647205Zenodo

slowkow/fibrotime: First release

10.5281/zenodo.3647204Zenodo

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