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The histone methyltransferase DOT1L prevents antigen-independent differentiation and safeguards epigenetic identity of CD8 + T cells

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.1920372117Source: DataRank Database

The histone methyltransferase DOT1L prevents antigen-independent differentiation and safeguards epigenetic identity of CD8 + T cells is a research paper published in Proceedings of the National Academy of Sciences (2020). On theSindex it has a DataRank of 0.596. It has been cited 52 times.

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0.596DataRank · unranked

Scored on demand from live citation data

Open Access52 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (5 grants)OA: bronzeTopics (47)IDs (PubMed)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 100%Citation Network 0%

Base Score Contribution

0.596

From this paper's citation signal

Citation Network Contribution

Citation network not refreshed for this result

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Authors (17)

Muhammad Assad Aslam ORCID,Mir Farshid Alemdehy ORCID,Teun van den Brand ORCID,Chelsea McLean ORCID,Hanneke Vlaming ORCID

Live enrichment

PubMed:32764145

KWF Kankerbestrijding

Grant: NKI2014-7232

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

Grant: NWO-VICI-016.130.627

ZonMw

Grant: Top 91213018

ZonMw

Grant: Top 91218022

Wellcome Trust

Grant: unidentified

unidentified

bronzeLicense: CC BY NC ND

publisherhttps://www.pnas.org/content/pnas/117/34/20706.full.pdf

publisherhttp://www.pnas.org/syndication/doi/10.1073/pnas.1920372117

publisherhttps://pnas.org/doi/pdf/10.1073/pnas.1920372117

repositoryhttps://research.vumc.nl/en/publications/4b380fc8-fdda-4de8-98c1-50952a6e7fe4

repositoryhttps://pure.amsterdamumc.nl/files/137964378/The-histone-methyltransferase-dot1l-prevents-antigen-independent-differentiation-and-safeguards-epigenetic-identity-of-c.pdf

Fields of Study

03 medical and health sciences0302 clinical medicineAnimalsAntigens, DifferentiationCD8-Positive T-LymphocytesCell DifferentiationEpigenesis, GeneticEpigenomicsFemaleHistone MethyltransferasesHistone-Lysine N-MethyltransferaseHistonesMaleMethyltransferasesMice

MeSH Terms

AnimalsAntigens, DifferentiationCD8-Positive T-LymphocytesCell DifferentiationEpigenesis, GeneticEpigenomicsFemaleHistone MethyltransferasesHistone-Lysine N-MethyltransferaseHistonesMaleMethyltransferasesMice

Keywords

H3K79me2EpigenomicsMaleepigeneticsT cellCell DifferentiationVirtual memoryDOT1LHistone-Lysine N-MethyltransferaseMethyltransferasesBiological SciencesCD8-Positive T-LymphocytesAntigens, DifferentiationEpigenesis, GeneticHistonesMiceHistone MethyltransferasesAnimalsFemale

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SDG 2: 2. Zero hungerSDG 3: 3. Good health