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Resetting proteostasis with ISRIB promotes epithelial differentiation to attenuate pulmonary fibrosis

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2101100118Source: DataRank Database

Resetting proteostasis with ISRIB promotes epithelial differentiation to attenuate pulmonary fibrosis is a research paper published in Proceedings of the National Academy of Sciences (2021). On theSindex it has a DataRank of 0.688. It has been cited 97 times.

N/A

0.688DataRank · unranked

Scored on demand from live citation data

Open Access97 citations

Cite:

Linked data & code

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (40 grants)Impact (FWCI 7.45)OA: greenTopics (64)IDs (PubMed, PMC, OpenAlex)Annotations (4)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 100%Citation Network 0%

Base Score Contribution

0.688

From this paper's citation signal

Citation Network Contribution

0

Citation network not refreshed for this result

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Authors (24)

Nikolay S. Markov ORCID,Ziyan Lu ORCID,Raul Piseaux Aillon,Saul Soberanes ORCID,Constance E. Runyan ORCID

Live enrichment

PubMed:33972447 PMC:PMC8157939 OpenAlex:https://openalex.org/W3163126369

HHS | NIH | National Institute of Environmental Health Sciences

Grant: ES013995

HHS | NIH | National Heart, Lung, and Blood Institute

Grant: HL071643

HHS | NIH | National Institute on Aging

Grant: AG049665

U.S. Department of Veterans Affairs

Grant: BX000201

HHS | NIH | National Heart, Lung, and Blood Institute

Grant: HL135124

HHS | NIH | National Heart, Lung, and Blood Institute

Grant: HL153312

HHS | NIH | National Institute of Allergy and Infectious Diseases

Grant: AI135964

HHS | NIH | National Heart, Lung, and Blood Institute

Grant: K08HL146943

HHS | NIH | National Heart, Lung, and Blood Institute

Grant: T32HL076139

HHS | NIH | National Heart, Lung, and Blood Institute

Grant: F32HL136111

HHS | NIH | National Institute on Aging

Grant: T32AG020506

NIA NIH HHS

Grant: P01 AG049665

NHLBI NIH HHS

Grant: P01 HL071643

NCI NIH HHS

Grant: P30 CA060553

NIGMS NIH HHS

Grant: R01 GM129312

NHLBI NIH HHS

Grant: R01 HL134800

BLRD VA

Grant: I01 BX000201

NIEHS NIH HHS

Grant: R01 ES013995

NIA NIH HHS

Grant: RF1 AG057296

NIH HHS

Grant: S10 OD010398

NHLBI NIH HHS

Grant: R01 HL153312

NHLBI NIH HHS

Grant: R56 HL135124

NIA NIH HHS

Grant: F31 AG071225

NIA NIH HHS

Grant: R37 AG026647

NIAID NIH HHS

Grant: U19 AI135964

National Institutes of Health

Grant: 1F32HL136111-01A1

A Systems Biology Approach to Mapping Aging in the lung

National Institutes of Health

Grant: 5T32HL076139-13

Training Program In Lung Sciences

National Institutes of Health

Grant: 1R01GM129312-01

Cadherin-catenin regulation in dividing epithelial cells

National Institutes of Health

Grant: 1R01HL134800-01A1

Wnt-beta-catenin cross interactions in alveolar macrophages and epithelial cells in persistence of SSc-ILD

National Institutes of Health

Grant: 5R01ES013995-02

Mechanisms of Particulate Matter Induced Death

National Institutes of Health

Grant: 1R56HL135124-01

Differential role of tissue-resident and monocyte-derived alveolar macrophages in the development of pulmonary fibrosis

National Institutes of Health

Grant: 5R01HL153312-04

Lung transplant injury drives chronic lung allograft dysfunction via recruitment ofmonocyte-derived alveolar macrophages

National Institutes of Health

Grant: 5P01HL071643-04

Pathophysiology of Alveolar Epithelial Lung Injury

National Institutes of Health

Grant: 5P30CA060553-12

The Robert H.Lurie Comprehensive Cancer Center

National Institutes of Health

Grant: 5K08HL146943-02

Single-Cell Transcriptomic Analysis to Identify Drivers of Pulmonary Fibrosis

National Institutes of Health

Grant: 1F31AG071225-01

Dysfunction of microglial proteostasis drives neuroinflammation and cognitive decline following pneumonia

National Institutes of Health

Grant: 5P01AG049665-05

Disordered Proteostasis as a Driver of Disease in the Aging Lung

National Institutes of Health

Grant: 1S10OD010398-01

Olympus FV1000MPE Multiphoton Microscope

National Institutes of Health

Grant: 5T32AG020506-03

Mechanisms of Aging and Dementia Training Program

National Institutes of Health

Grant: 5U19AI135964-02

Successful Clinical Response In Pneumonia Therapy (SCRIPT) Systems Biology Center

FWCI

7.45

Citation Percentile

1.0%

Citation Trend

2020

2021

2022

2023

2024

2025

2026

greenLicense: cc-by-nc-nd

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8157939

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8157939

publisherhttp://www.pnas.org/syndication/doi/10.1073/pnas.2101100118

publisherhttps://pnas.org/doi/pdf/10.1073/pnas.2101100118

journalhttps://doi.org/10.1073/pnas.2101100118

Fields of Study

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisInhalation and Respiratory Drug DeliveryExtracellular vesicles in disease0301 basic medicine0303 health sciences03 medical and health sciencesAcetamidesAge FactorsAlveolar Epithelial CellsAnimalsAsbestosBleomycinCell DifferentiationCell MovementCyclohexylaminesMacrophages, AlveolarMiceMice, Inbred C57BLProteostasisPulmonary FibrosisStress, Physiological

MeSH Terms

ProteostasisAcetamidesAge FactorsAnimalsAsbestosBleomycinCell DifferentiationCell MovementCyclohexylaminesMice, Inbred C57BLPulmonary FibrosisStress, PhysiologicalMacrophages, AlveolarMiceAlveolar Epithelial Cells

Keywords

ProteostasisPulmonary fibrosisIdiopathic pulmonary fibrosisFibrosisImmunologyInflammationCell biologyCancer researchBiologyMedicineLungPathologyInternal medicineIsribCyclohexylaminesAge FactorsAsbestosCell DifferentiationBiological SciencesMice, Inbred C57BLBleomycinMiceCell MovementStress, PhysiologicalAlveolar Epithelial CellsAcetamidesMacrophages, AlveolarAnimals

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being