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Shock-and-kill versus block-and-lock: Targeting the fluctuating and heterogeneous HIV-1 gene expression

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2103692118Source: DataRank Database

Shock-and-kill versus block-and-lock: Targeting the fluctuating and heterogeneous HIV-1 gene expression is a research paper published in Proceedings of the National Academy of Sciences (2021). On theSindex it has a DataRank of 0. It has been cited 27 times.

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Open Access27 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (16 grants)Impact (FWCI 2.89)OA: bronzeTopics (28)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (2)

Ya‐Chi Ho ORCID,Yang-Hui Jimmy Yeh ORCID

Live enrichment

PubMed:33758027 PMC:PMC8072369 OpenAlex:https://openalex.org/W3136035560

NIDA NIH HHS

Grant: U01 DA053628

NIDA NIH HHS

Grant: R61 DA047037

NIAID NIH HHS

Grant: P50 AI150464

NIDA NIH HHS

Grant: R01 DA051906

NIDA NIH HHS

Grant: UM1 DA051410

NIAID NIH HHS

Grant: UM1 AI126620

NIAID NIH HHS

Grant: R01 AI141009

NIAID NIH HHS

Grant: R37 AI147868

NCATS NIH HHS

Grant: UL1 TR001863

National Institutes of Health

Grant: 3P50AI150464-14S1

Center for the Structural Biology of Cellular Host Elements in Egress, Trafficking, and Assembly of HIV (CHEETAH Center)

National Institutes of Health

Grant: 5UM1AI126620-05

BEAT-HIV: Delaney Collaboratory to Cure HIV-1 Infection by Combination Immunotherapy

National Institutes of Health

Grant: 5R61DA047037-03

Evaluating the role of opioid medication assisted therapies in HIV-1 Persistence for persons living with HIV and opioid use disorders

National Institutes of Health

Grant: 5UM1DA051410-03

The Y-SCORCH Data Generation Center at Yale for Single-Cell Opioid Responses in the Context of HIV

National Institutes of Health

Grant: 1R01DA051906-01

A Big Data Approach to Identify Epigenetic, Transcriptomic, and Network Dynamics as Immune Dysfunction Drivers Associated with HIV Infection and Substance Use Disorder

National Institutes of Health

Grant: 5R01AI141009-07

Role of clonal expansion in HIV-1 persistence

National Institutes of Health

Grant: 5R37AI147868-05

The HUSH complex in HIV-1 latency

FWCI

2.89

Citation Percentile

0.9%

Citation Trend

2021

2022

2023

2024

2025

2026

bronzeLicense: https://www.pnas.org/site/aboutpnas/licenses.xhtml

journalhttps://www.pnas.org/doi/pdf/10.1073/pnas.2103692118

publisherhttps://www.pnas.org/doi/pdf/10.1073/pnas.2103692118

publisherhttps://pnas.org/doi/pdf/10.1073/pnas.2103692118

journalhttps://doi.org/10.1073/pnas.2103692118

repositoryhttps://pubmed.ncbi.nlm.nih.gov/33758027

Fields of Study

HIV Research and TreatmentCRISPR and Genetic Engineering0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

HumansVirus ActivationHIV-1HIV InfectionsGene ExpressionGene Expression Regulation, ViralVirus LatencyAnti-HIV Agents

Keywords

Human immunodeficiency virus (HIV)Gene expressionBiologyBlock (permutation group theory)GeneticsGeneVirologyComputational biologyGene Expression Regulation, ViralAnti-HIV AgentsHIV-1HumansHIV InfectionsVirus ActivationVirus Latency

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being