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A functional mammalian display screen identifies rare antibodies that stimulate NK cell–mediated cytotoxicity

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2104099118Source: DataRank Database

A functional mammalian display screen identifies rare antibodies that stimulate NK cell–mediated cytotoxicity is a research paper published in Proceedings of the National Academy of Sciences (2021). On theSindex it has a DataRank of 0. It has been cited 6 times.

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Open Access6 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (11 grants)OA: bronzeTopics (67)IDs (PubMed, PMC)SDGs (1)

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Authors (5)

Cigall Kadoch ORCID,James L. Rubenstein ORCID,Lewis L. Lanier ORCID,James A. Wells ORCID,Emily L. Kang ORCID

Live enrichment

PubMed:34330834 PMC:PMC8346823

HHS | National Institutes of Health

Grant: 5R35GM122451

HHS | National Institutes of Health

Grant: AI068129

HHS | NIH | National Cancer Institute

Grant: R01CA248323

Center for Strategic Scientific Initiatives, National Cancer Institute

Grant: R01CA139-83-01A1

NIGMS NIH HHS

Grant: R35 GM122451

NCI NIH HHS

Grant: R01 CA139083

NCI NIH HHS

Grant: R01 CA239462

NIAID NIH HHS

Grant: R01 AI068129

National Institutes of Health

Grant: 5R01AI068129-15

NK Cell Receptors and their Ligands

National Institutes of Health

Grant: 5R35GM122451-05

Discovering how oncogenes remodel the surfaceome of cells

National Institutes of Health

Grant: 5R01CA248323-04

New protein engineering-based tools and technologies for characterizing cell surface proteolysis in cancer cells for novel neo-epitope biomarkers and drug targets

bronzeLicense: https://www.pnas.org/site/aboutpnas/licenses.xhtml

publisherhttps://www.pnas.org/content/pnas/118/31/e2104099118.full.pdf

publisherhttp://www.pnas.org/syndication/doi/10.1073/pnas.2104099118

publisherhttps://pnas.org/doi/pdf/10.1073/pnas.2104099118

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8346823

https://doi.org/10.1073/pnas.2104099118

Fields of Study

0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

Killer Cells, NaturalCell Line, TumorHumansLymphoma, B-CellBreast NeoplasmsReceptors, Cell SurfaceReceptors, IgGAntibodiesReproducibility of ResultsAntibody AffinityAntibody-Dependent Cell CytotoxicityGene Expression RegulationGene Expression Regulation, NeoplasticFemaleInterferon-gammaGPI-Linked ProteinsRituximabErb-b2 Receptor Tyrosine Kinases

Keywords

AntibodyImmunotherapyNatural killer cellsBispecific AntibodiesLymphomaAntibody AffinityErbB-2Receptors2.1 Biological and endogenous factorsKiller CellsAetiologyCancerTumorGene Expression Regulation, NeoplasticKiller Cells, NaturalCell SurfaceNaturalFemaleDevelopment of treatments and therapeutic interventionsRituximabReceptorLymphoma, B-CellIgG1.1 Normal biological development and functioningBreast NeoplasmsReceptors, Cell SurfaceGPI-Linked ProteinsErb-b2 Receptor Tyrosine KinasesAntibodiesCell LineVaccine RelatedInterferon-gammaRare DiseasesUnderpinning researchCell Line, TumorBreast CancerHumansNeoplastic5.2 Cellular and gene therapiesReceptors, IgGB-CellAntibody-Dependent Cell CytotoxicityReproducibility of ResultsOrphan DrugGene Expression RegulationImmunization

Sustainable Development Goals

SDG 3: 3. Good health