James A. Wells

Also affiliated with Cellular Research (United States)

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 66 papers. Top paper: “Modular cytokine receptor-targeting chimeras for targeted degradation of cell surface and extracellular proteins”.

Modular cytokine receptor-targeting chimeras for targeted degradation of cell surface and extracellular proteins

Nature Biotechnology(2022)10.1038/s41587-022-01456-2

N/A

0.834DataRank · unranked

259 citations

Josef A. Gramespacher, James R. Byrnes, Fernando Salangsang, Juan A. Cámara, Adam D. Cotton +3 more

Adaptor-Specific Antibody Fragment Inhibitors for the Intracellular Modulation of p97 (VCP) Protein–Protein Interactions

Journal of the American Chemical Society(2022)10.1021/jacs.2c03665

N/A

0.678DataRank · unranked

14 citations

Yu‐Hsuan Kuo, Mengqi Zhong, Jianchao Zhang, Xin Zhou, Lijuan Xing +4 more

Competitive SARS-CoV-2 Serology Reveals Most Antibodies Targeting the Spike Receptor-Binding Domain Compete for ACE2 Binding

mSphere(2020)10.1128/msphere.00802-20

N/A

0.650DataRank · unranked

75 citations

Xin Zhou, Irene Lui, Susanna K. Elledge, Jeff E. Glasgow, Shion A. Lim +7 more

BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2

Nature Cell Biology(2022)10.1038/s41556-021-00821-8

N/A

0.639DataRank · unranked

70 citations

Quang Tran, Rémy Robinot, Lucia Carrau, Veronica V. Rezelj, Alice Mac Kain +22 more

Cleavage of talin by calpain promotes platelet-mediated fibrin clot contraction

Blood Advances(2021)10.1182/bloodadvances.2021004582

N/A

0.614DataRank · unranked

18 citations

Kathleen S. Molnar, Nicholas J. Agard, Rustem I. Litvinov, Oleg V. Kim, James A. Wells +4 more

Trimeric SARS-CoV-2 Spike interacts with dimeric ACE2 with limited intra-Spike avidity

10.1101/2020.05.21.109157

N/A

0.590DataRank · unranked

50 citations

Xin Zhou, Shion A. Lim, Susanna K. Elledge, Paige Solomon, Nicholas J. Rettko +16 more

Theranostic Targeting of CUB Domain–Containing Protein 1 (CDCP1) in Multiple Subtypes of Bladder Cancer

Clinical Cancer Research(2023)10.1158/1078-0432.ccr-22-1973

N/A

0.553DataRank · unranked

11 citations

Kai Trepka, Sasank Sakhamuri, Alberto Carretero-González, Jun Zhu, Emily A. Egusa +9 more

Identification of a Covalent Molecular Inhibitor of Anti-apoptotic BFL-1 by Disulfide Tethering

Cell chemical biology(2020)10.1016/j.chembiol.2020.04.004

N/A

0.546DataRank · unranked

37 citations

Zachary J. Hauseman, Daniel T. Cohen, T.J. Rettenmaier, Susan Lee, Annissa J. Huhn +11 more

Redox priming promotes Aurora A activation during mitosis

Science Signaling(2020)10.1126/scisignal.abb6707

N/A

0.524DataRank · unranked

32 citations

Vladimir Joukov, T.J. Rettenmaier, Akiko Kumagai, William G. Dunphy, James A. Wells +2 more

SARS-CoV-2 antibody magnitude and detectability are driven by disease severity, timing, and assay

medRxiv(2021)10.1101/2021.03.03.21251639

N/A

0.520DataRank · unranked

31 citations

Saki Takahashi, Jill Hakim, J. Daniel Kelly, Leonel Torres, Nikita S. Iyer +40 more

CUB Domain-Containing Protein 1 (CDCP1) Is a Target for Radioligand Therapy in Castration-Resistant Prostate Cancer, including PSMA Null Disease

Clinical Cancer Research(2022)10.1158/1078-0432.ccr-21-3858

N/A

0.515DataRank · unranked

30 citations

Shalini Chopra, Kai Trepka, Yung-Hua Wang, Sasank Sakhamuri, Nima Hooshdaran +18 more

Antibody discovery identifies regulatory mechanisms of protein arginine deiminase 4

Nature Chemical Biology(2024)10.1038/s41589-023-01535-8

N/A

0.500DataRank · unranked

27 citations

Sophie Kong, Allison Maker, Soumya G. Remesh, Kevin Leung, Kliment A. Verba +2 more

Discovery of VH domains that allosterically inhibit ENPP1

Nature Chemical Biology(2023)10.1038/s41589-023-01368-5

N/A

0.477DataRank · unranked

23 citations

Colton J. Bracken, Jacqueline A. Carozza, Haoqing Wang, Elizabeth P. Young, Alon Wellner +5 more

Mechanism-guided engineering of a minimal biological particle for genome editing

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2413519121

N/A

0.470DataRank · unranked

22 citations

Julia Peukes, Alisha Baldwin, Zhiwei Wayne Xue, Sidney Hwang, Robert R. Stickels +7 more

Multi-scale photocatalytic proximity labeling reveals cell surface neighbors on and between cells

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.28.564055

N/A

0.425DataRank · unranked

16 citations

Kaitlin Schaefer, Irene Lui, Zi Yao, Andrea Fossati, Danielle L. Swaney +4 more

Challenges in the discovery of tumor-specific alternative splicing-derived cell-surface antigens in glioma

Scientific Reports(2024)10.1038/s41598-024-56684-0

N/A

0.406DataRank · unranked

14 citations

Lin Wang, Kevin Leung, Albert Wang, Senthilnath Lakshmanachetty, Marco Gallus +19 more

β-Amyloid induces microglial expression of GPC4 and APOE leading to increased neuronal tau pathology and toxicity

Molecular Neurodegeneration(2025)10.1186/s13024-025-00883-4

N/A

0.292DataRank · unranked

6 citations

Thaddeus K. Weigel, Jesseca M. Chung, Sarah K. Kaufman, Brandon I. Apresa, James R. Byrnes +17 more

Challenges in the discovery of tumor-specific alternative splicing-derived cell-surface antigens in glioma

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.26.564156

N/A

0.269DataRank · unranked

5 citations

Lin Wang, Kevin Leung, Albert Wang, Senthilnath Lakshmanachetty, Marco Gallus +19 more

Computational pipeline provides mechanistic understanding of Omicron variant of concern neutralizing engineered ACE2 receptor traps

Structure(2023)10.1016/j.str.2023.01.009

N/A

0.241DataRank · unranked

4 citations

Gregory E. Merz, Axel F. Brilot, Un Seng Chio, Alexandrea N. Rizo, Thomas H. Pospiech +21 more

CRISPRi-based screen of Autism Spectrum Disorder risk genes in microglia uncovers roles of ADNP in microglia endocytosis and synaptic pruning

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.06.01.596962

N/A

0.208DataRank · unranked

3 citations

Amanda McQuade, Venus Hagan, Weiwei Liang, Nina M. Dräger, Sydney M. Sattler +9 more

High-affinity CD16A polymorphism associated with reduced risk ofsevere COVID-19

JCI Insight(2025)10.1172/jci.insight.191314

N/A

0.104DataRank · unranked

1 citations

Tasha Tsao, Irene Lui, Shion A. Lim, Yapeng Su, Ernie Chen +51 more

Cell-surface tethered promiscuous biotinylators enable small-scale surface proteomics of human exosomes

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.22.461393

N/A

0DataRank · unranked

1 citations

Susanna K. Elledge, Jiuling Yang, James R. Byrnes, Jeff E. Glasgow, Robert Blelloch +2 more

CUB domain containing protein 1 (CDPC1) is a target for radioligand therapy in castration resistant prostate cancer

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.06.17.448569

N/A

0DataRank · unranked

0 citations

Kai Trepka, Yung-Hua Wang, Shalini Chopra, Nima Hooshdaran, Hyun‐Jung Kim +14 more

Hypoxia is a dominant remodeler of the CD8 + T cell surface proteome relative to activation and regulatory T cell-mediated suppression

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.06.07.447379

N/A

0DataRank · unranked

0 citations

Amy M. Weeks, Eric Shifrut, Julia Carnevale, Lisa L. Kirkemo, Alan Ashworth +3 more

Engineering luminescent biosensors for point-of-care SARS-CoV-2 antibody detection

Nature Biotechnology(2021)10.1038/s41587-021-00878-8

N/A

0DataRank · unranked

144 citations

Xin Zhou, James R. Byrnes, Alexander J. Martinko, Irene Lui, Katarina Pance +14 more

Ribosome stalling during selenoprotein translation exposes a ferroptosis vulnerability

Nature Chemical Biology(2022)10.1038/s41589-022-01033-3

N/A

0DataRank · unranked

134 citations

Lucas Ferguson, Kirandeep K. Deol, Melissa A. Roberts, Leslie Magtanong, Joseph M. Hendricks +10 more

The surfaceome of multiple myeloma cells suggests potential immunotherapeutic strategies and protein markers of drug resistance

Nature Communications(2022)10.1038/s41467-022-31810-6

N/A

0DataRank · unranked

130 citations

Bonell Patiño-Escobar, Sami T. Tuomivaara, Yu-Hsiu T. Lin, Matthew A. Nix, Kevin Leung +24 more

Roadmap for Optimizing and Broadening Antibody-Based PROTACs for Degradation of Cell Surface Proteins

ACS Chemical Biology(2022)10.1021/acschembio.2c00185

N/A

0DataRank · unranked

96 citations

Adam D. Cotton, Paul W. W. Burroughs, Ian B. Seiple, James A. Wells, Josef A. Gramespacher

SARS-CoV-2 antibody magnitude and detectability are driven by disease severity, timing, and assay

Science Advances(2021)10.1126/sciadv.abh3409

N/A

0DataRank · unranked

151 citations

Saki Takahashi, Jill Hakim, J. Daniel Kelly, Leonel Torres, Nikita S. Iyer +41 more

Targeting a proteolytic neoepitope on CUB domain containing protein 1 (CDCP1) for RAS-driven cancers

Journal of Clinical Investigation(2022)10.1172/jci154604

N/A

0DataRank · unranked

39 citations

Jie Zhou, Alexander J. Martinko, Yung-Hua Wang, E.V. Filippova, Veronica Steri +9 more

MEK inhibition enhances presentation of targetable MHC-I tumor antigens in mutant melanomas

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2208900119

N/A

0DataRank · unranked

38 citations

Nicholas J. Rettko, Owen Leddy, Joshua M. Mesfin, Eric N. Brown, Shannon L. Winski +4 more

Mapping proteolytic neo-N termini at the surface of living cells

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.02.23.961904

N/A

0DataRank · unranked

3 citations

James R. Byrnes, Irene Lui, James A. Wells, Amy M. Weeks

Direct Identification of Proteolytic Cleavages on Living Cells Using a Glycan-Tethered Peptide Ligase

ACS Central Science(2022)10.1021/acscentsci.2c00899

N/A

0DataRank · unranked

20 citations

Irene Lui, James R. Byrnes, Emily L. Kang, Jie Zhou, Amy M. Weeks +2 more

Deep profiling of protease substrate specificity enabled by dual random and scanned human proteome substrate phage libraries

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.09.086264

N/A

0DataRank · unranked

4 citations

Shantao Li, Kevin Leung, Brian D. O’Donovan, James Zou, Joseph L. DeRisi +2 more

Discovery Proteomics Analysis Determines That Driver Oncogenes Suppress Antiviral Defense Pathways Through Reduction in Interferon-β Autocrine Stimulation

Molecular & Cellular Proteomics(2022)10.1016/j.mcpro.2022.100247

N/A

0DataRank · unranked

9 citations

Lisa L. Kirkemo, Gary M. Wilson, Kevin Leung, M. Almond, Leanne C. Sayles +5 more

Using Split Luminescent Biosensors for SARS‐CoV‐2 Antibody Detection in Serum, Plasma, and Blood Samples

Current Protocols(2022)10.1002/cpz1.521

N/A

0DataRank · unranked

7 citations

Ian Eigl, Maíra Phelps, Khayla McClinton, Xin Zhou, Kevin Leung +3 more

MEK inhibition enhances presentation of targetable MHC-I tumor antigens in mutant melanomas

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.01.10.475285

N/A

0DataRank · unranked

2 citations

Nicholas J. Rettko, Owen Leddy, Joshua M. Mesfin, Eric N. Brown, Shannon L. Winski +4 more

A general approach for selection of epitope-directed binders to proteins

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.24.513434

N/A

0DataRank · unranked

0 citations

Chau Q. Le, Yun Zhang, James A. Wells, Jie Zhou

Engineering luminescent biosensors for point-of-care SARS-CoV-2 antibody detection

Estudios de derecho judicial(2020)10.1101/2020.08.17.20176925

N/A

0DataRank · unranked

15 citations

Xin Zhou, James R. Byrnes, Alexander J. Martinko, Irene Lui, Katarina Pance +14 more

A SARS-CoV-2 serological assay to determine the presence of blocking antibodies that compete for human ACE2 binding

medRxiv(2020)10.1101/2020.05.27.20114652

N/A

0DataRank · unranked

18 citations

Xin Zhou, Irene Lui, Susanna K. Elledge, Jeff E. Glasgow, Shion A. Lim +6 more

Quitting smoking after a cancer diagnosis is associated with high-risk neutrophil-to-lymphocyte ratio among tobacco use-related cancer survivors

Scientific Reports(2023)10.1038/s41598-023-27624-1

N/A

0DataRank · unranked

7 citations

Katherine Kwong, James A. Wells, A. David Edwards, Zhong Chen, Tung‐Sung Tseng +2 more

Engineered ACE2 receptor traps potently neutralize SARS-CoV-2

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.2016093117

N/A

0DataRank · unranked

265 citations

Jeff E. Glasgow, Daniel Limonta, Paige Solomon, Irene Lui, Sunny Zhang +15 more

Secreted HLA-Fc fusion profiles immunopeptidome in hypoxic PDAC and cellular senescence

PNAS Nexus(2023)10.1093/pnasnexus/pgad400

N/A

0DataRank · unranked

5 citations

Lisa L. Kirkemo, James A. Wells, Nicholas J. Rettko

Engineered ACE2 receptor traps potently neutralize SARS-CoV-2

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.07.31.231746

N/A

0DataRank · unranked

38 citations

Jeff E. Glasgow, Daniel Limonta, Paige Solomon, Irene Lui, Yang Zhang +15 more

Theranostic Targeting of CUB Domain Containing Protein 1 (CDCP1) in Pancreatic Cancer

Clinical Cancer Research(2020)10.1158/1078-0432.ccr-20-0268

N/A

0DataRank · unranked

36 citations

Yung-Hua Wang, Jeremy Sharib, Junnian Wei, Ning Zhao, Yangjie Huang +13 more

Multiscale photocatalytic proximity labeling reveals cell surface neighbors on and between cells

Science(2024)10.1126/science.adl5763

N/A

0DataRank · unranked

123 citations

Kaitlin Schaefer, Irene Lui, Zi Yao, Andrea Fossati, Danielle L. Swaney +4 more

Oxidative cyclization reagents reveal tryptophan cation–π interactions

Nature(2024)10.1038/s41586-024-07140-6

N/A

0DataRank · unranked

68 citations

Patrick J. Moon, Steven W. M. Crossley, Amanda J. Bischoff, Dan He, Gen Li +9 more

Split enzymes: Design principles and strategy

Methods in enzymology on CD-ROM/Methods in enzymology(2020)10.1016/bs.mie.2020.05.001

N/A

0DataRank · unranked

13 citations

James A. Wells, Shion A. Lim

Transcobalamin receptor antibodies in autoimmune vitamin B12 central deficiency

Science Translational Medicine(2024)10.1126/scitranslmed.adl3758

N/A

0DataRank · unranked

22 citations

Thomas Ngo, Camille Fouassier, Maura A. McDonagh, Brandon B. Holmes, Christopher M. Bartley +41 more

Systematic identification of engineered methionines and oxaziridines for efficient, stable, and site-specific antibody bioconjugation

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.1920561117

N/A

0DataRank · unranked

58 citations

Hai L. Tran, Alec H. Christian, Veronica Steri, Byron Hann, F. Dean Toste +3 more

Covalent inhibition of pro-apoptotic BAX

Nature Chemical Biology(2024)10.1038/s41589-023-01537-6

N/A

0DataRank · unranked

23 citations

Peiwen Shi, Christina M. Camara, Daniel T. Cohen, T.J. Rettenmaier, Utsarga Adhikary +8 more

Deep profiling of protease substrate specificity enabled by dual random and scanned human proteome substrate phage libraries

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.2009279117

N/A

0DataRank · unranked

59 citations

Shantao Li, Kevin Leung, Brian D. O’Donovan, James Zou, Joseph L. DeRisi +2 more

PVRL2 Suppresses Antitumor Immunity through PVRIG- and TIGIT-independent Pathways

Cancer Immunology Research(2024)10.1158/2326-6066.cir-23-0722

N/A

0DataRank · unranked

12 citations

Li Wang, James R. Byrnes, Lisa L. Kirkemo, Hannah Driks, Cassandra D. Belair +6 more

A general approach for selection of epitope-directed binders to proteins

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2317307121

N/A

0DataRank · unranked

12 citations

Chau Q. Le, Yun Zhang, James A. Wells, Jie Zhou

Chemoproteomics reveals immunogenic and tumor-associated cell surface substrates of ectokinase CK2α

Cell chemical biology(2024)10.1016/j.chembiol.2024.07.018

N/A

0DataRank · unranked

4 citations

Sophie Kong, Jeff E. Glasgow, Rita P. Loudermilk, Lisa L. Kirkemo, Fangzhu Zhao +6 more

Spatiotemporal photocatalytic proximity labeling proteomics reveals ligand-activated extracellular and intracellular EGFR neighborhoods

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.12.21.629933

N/A

0DataRank · unranked

1 citations

Wayne Ngo, Yu‐Ting Chou, Harry X. Wu, Katherine J. Susa, Young-wook Jun +4 more

PVRL2 Suppresses Anti-tumor Immunity Through PVRIG- and TIGIT-Independent Pathways

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.26.577132

N/A

0DataRank · unranked

0 citations

Li Wang, James R. Byrnes, Lisa L. Kirkemo, Hannah Driks, Cassandra D. Belair +6 more

Chemoproteomics reveals immunogenic and tumor-associated cell surface substrates of ectokinase CK2α

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.20.585970

N/A

0DataRank · unranked

0 citations

Sophie Kong, Jeff E. Glasgow, Rita P. Loudermilk, Lisa L. Kirkemo, Fangzhu Zhao +6 more

Hijacking Extracellular Targeted Protein Degrader–Drug Conjugates for Enhanced Drug Delivery

Journal of the American Chemical Society(2025)10.1021/jacs.5c15047

N/A

0DataRank · unranked

15 citations

Yan Wu, Kaitlin Schaefer, Yun Zhang, Kun Miao, Zi Yao +8 more

Temporal photoproximity labeling of ligand-activated EGFR neighborhoods using MultiMap

Nature Chemical Biology(2025)10.1038/s41589-025-02076-y

N/A

0DataRank · unranked

7 citations

Wayne Ngo, Yu‐Ting Chou, Harry X. Wu, Katherine J. Susa, Young-wook Jun +4 more

De Novo Design of Proteins That Bind Naphthalenediimides, Powerful Photooxidants with Tunable Photophysical Properties

Journal of the American Chemical Society(2025)10.1021/jacs.4c18151

N/A

0DataRank · unranked

13 citations

Zhi Lin, Sophia K. Tan, Jiaqi Zhu, Zachary X. W. Widel, Ian Bakanas +8 more

Broad and thematic remodeling of the surfaceome and glycoproteome on isogenic cells transformed with driving proliferative oncogenes

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.1917947117

N/A

0DataRank · unranked

85 citations

Gary M. Wilson, Lisa L. Kirkemo, Nicholas M. Riley, Joshua J. Coon, James A. Wells +1 more

A cytokine receptor-targeting chimera (kineTAC) toolbox for expanding extracellular targeted protein degradation

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.09.02.673832

N/A

0DataRank · unranked

0 citations

Zi Yao, Brandon B. Holmes, Fangzhu Zhao, Yun Zhang, Emilio Ferrara +4 more

A functional mammalian display screen identifies rare antibodies that stimulate NK cell–mediated cytotoxicity

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2104099118

N/A

0DataRank · unranked

6 citations

Cigall Kadoch, James L. Rubenstein, Lewis L. Lanier, James A. Wells, Emily L. Kang

ReScan, a Multiplex Diagnostic Pipeline, Pans Human Sera for SARS-CoV-2 Antigens

Cell Reports Medicine(2020)10.1016/j.xcrm.2020.100123

N/A

0DataRank · unranked

97 citations

Jayant V. Rajan, Kevin A. Yamauchi, Sabrina A Mann, Rita P. Loudermilk, Gavin M. Sowa +17 more

BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.01.19.427194

N/A

0DataRank · unranked

13 citations

Quang Tran, Rémy Robinot, Lucía Carrau, Veronica V. Rezelj, Alice Mac Kain +22 more