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From sequence to scaffold: Computational design of protein nanoparticle vaccines from AlphaFold2-predicted building blocks

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2409566122Source: DataRank Database

From sequence to scaffold: Computational design of protein nanoparticle vaccines from AlphaFold2-predicted building blocks is a research paper published in Proceedings of the National Academy of Sciences (2025). On theSindex it has a DataRank of 0. It has been cited 8 times.

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Open Access8 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (4 grants)Impact (FWCI 3.46)OA: hybridTopics (37)IDs (PubMed, PMC, OpenAlex)Annotations (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (11)

Naveen Jasti,Annie Dosey ORCID,Joel D. Allen ORCID,Rebecca A. Gillespie ORCID,Jackson McGowan

Live enrichment

PubMed:41183183 PMC:PMC12626006 OpenAlex:https://openalex.org/W4415823398

Bill and Melinda Gates Foundation

Grant: INV-043758

HHS | NIH

Grant: P01AI167966

Gates Foundation

Grant: INV-010680

Gates Foundation

Grant: INV-008813

FWCI

3.46

Citation Percentile

0.9%

Citation Trend

2025

2026

hybridLicense: cc-by

journalhttps://www.pnas.org/doi/pdf/10.1073/pnas.2409566122

publisherhttps://www.pnas.org/doi/pdf/10.1073/pnas.2409566122

publisherhttps://pnas.org/doi/pdf/10.1073/pnas.2409566122

journalhttps://doi.org/10.1073/pnas.2409566122

repositoryhttps://pubmed.ncbi.nlm.nih.gov/41183183

Fields of Study

vaccines and immunoinformatics approachesImmunotherapy and Immune ResponsesBiochemical and Structural CharacterizationNanoparticlesAnimalsMiceCryoelectron MicroscopyInfluenza VaccinesComputational BiologyModels, MolecularHemagglutinin Glycoproteins, Influenza VirusVaccinesMachine LearningNanovaccines

MeSH Terms

Machine LearningNanovaccinesAnimalsInfluenza VaccinesModels, MolecularVaccinesHemagglutinin Glycoproteins, Influenza VirusComputational BiologyCryoelectron MicroscopyMiceNanoparticles

Keywords

Protein designIcosahedral symmetryImmunogenNanoparticleProtein sequencingSequence (biology)Protein engineeringDomain (mathematical analysis)VaccinesInfluenzaNanoparticlesMachine Learning

From sequence to scaffold: Computational design of protein nanoparticle vaccines from AlphaFold2-predicted building blocks

FAIR Checklist

Authors (11)

Funding (4 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)