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Novel drug discovery platform for spinocerebellar ataxia, using fluorescence technology targeting β-III-spectrin

Journal of Biological Chemistry(2020)10.1074/jbc.ra120.015417Source: DataRank Database

Novel drug discovery platform for spinocerebellar ataxia, using fluorescence technology targeting β-III-spectrin is a research paper published in Journal of Biological Chemistry (2020). On theSindex it has a DataRank of 0. It has been cited 11 times.

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Open Access11 citations

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Enrichment:Funding (8 grants)OA: hybridTopics (31)IDs (PubMed, PMC)Annotations (2)

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Open Access

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Reusable (0/3)

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Authors (8)

Anna Andrick,Sarah A. Denha,Bengt Svensson ORCID,Piyali Guhathakurta,David D. Thomas ORCID

Live enrichment

PubMed:33839680 PMC:PMC7948455

National Institutes of Health

Grant: R37AG026160

National Institutes of Health

Grant: R01HL139065

National Institutes of Health

Grant: R01GM044757

National Institutes of Health

Grant: R15NS116511

National Institutes of Health

Grant: R61NS111075

National Institutes of Health

Grant: GM027906

NIGMS NIH HHS

Grant: R01 GM027906

NINDS NIH HHS

Grant: R33 NS111075

hybridLicense: cc-by

publisherhttps://doi.org/10.1074/jbc.ra120.015417

publisherhttps://api.elsevier.com/content/article/PII:S0021925820002112?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0021925820002112?httpAccept=text/plain

publisherhttps://syndication.highwire.org/content/doi/10.1074/jbc.RA120.015417

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7948455

MeSH Terms

HumansSpinocerebellar AtaxiasActinsSpectrinLuminescent ProteinsGreen Fluorescent ProteinsRecombinant Fusion ProteinsNeuroprotective AgentsMarine ToxinsFluorescence Resonance Energy TransferReproducibility of ResultsGene ExpressionBinding SitesProtein BindingKineticsMutationModels, BiologicalModels, MolecularProtein Interaction Domains and MotifsHigh-Throughput Screening AssaysHEK293 CellsProtein Conformation, alpha-HelicalProtein Conformation, beta-StrandRed Fluorescent Protein

Keywords

FluorescenceDrug screeningFluorescence lifetimeTime-resolved FretActin BindingHek293-6e CellsSwinholide A