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Molecular imaging of Alzheimer’s disease–related gamma-secretase in mice and nonhuman primates

The Journal of Experimental Medicine(2020)10.1084/jem.20182266Source: DataRank Database

Molecular imaging of Alzheimer’s disease–related gamma-secretase in mice and nonhuman primates is a research paper published in The Journal of Experimental Medicine (2020). On theSindex it has a DataRank of 0. It has been cited 32 times.

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Scored on demand from live citation data

Open Access32 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (25 grants)Impact (FWCI 2.15)OA: greenTopics (62)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (15)

Changning Wang ORCID,Hsiao‐Ying Wey ORCID,Yingxia Liang ORCID,Zude Chen,Se Hoon Choi ORCID

Live enrichment

PubMed:32936886 PMC:PMC7553790 OpenAlex:https://openalex.org/W3087696848

National Institutes of Health

Grant: P01 AG015379

National Institutes of Health

Grant: U01 NS074501

National Institutes of Health

Grant: R01AG055784

National Institutes of Health

Grant: R21AG062913

Massachusetts General Hospital

Grant: P41EB015896

National Institutes of Health

Grant: S10RR017208

National Institutes of Health

Grant: S10RR026666

National Institutes of Health

Grant: S10RR022976

National Institutes of Health

Grant: S10RR019933

National Institutes of Health

Grant: S10RR023401

NIH HHS

Grant: S10 OD023517

NIDA NIH HHS

Grant: R03 DA048123

National Institutes of Health

Grant: 1S10RR017208-01A1

Cyclotron and Radiochemistry

National Institutes of Health

Grant: 1S10RR019933-01A1

PET CAMERA FOR BRAIN IMAGING: NEUROSCIENCE

National Institutes of Health

Grant: 1S10RR023401-01A2

A Storage Area Network for Structural and Functional Image Analysis

National Institutes of Health

Grant: 1S10RR026666-01

Carbon-11 Radiopharmaceutical Production System

National Institutes of Health

Grant: 5R01AG055784-03

Characterizing the roles of novel soluble GSMs in AD pathology.

National Institutes of Health

Grant: 5U01NS074501-03

Optimization of Soluble Gamma-secretase Modulators for the Treatment of Alzheimer

National Institutes of Health

Grant: 1S10RR022976-01

Combined MRI/PET Imager for Simultaneous Acquisition of PET/MRI Data

National Institutes of Health

Grant: 2P01AG015379-11

Presenilin Biology and the Mechanism of Alzheimers Disease

National Institutes of Health

Grant: 5P41EB015896-18

Center for Functional Imaging Technologies

National Institutes of Health

Grant: 5R21AG062913-02

Molecular imaging of PS1/gamma-secretase and analysis of Alzheimer's disease.

Cure Alzheimer's Fund

Massachusetts General Hospital

National Institutes of Health

FWCI

2.15

Citation Percentile

0.9%

Influential Citations

Citation Trend

2021

2022

2023

2024

2025

2026

greenLicense: CC BY NC SA

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7553790

HYBRIDhttps://doi.org/10.1084/jem.20182266

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7553790

publisherhttps://rupress.org/jem/article-pdf/doi/10.1084/jem.20182266/1815901/jem_20182266.pdf

repositoryhttps://pubmed.ncbi.nlm.nih.gov/32936886

Fields of Study

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration MechanismsNeuroscience and Neuropharmacology ResearchBiologyMedicine0301 basic medicine0303 health sciences03 medical and health sciencesAlzheimer DiseaseAmyloid Precursor Protein SecretasesAnimalsBrainHumansMacaca mulattaMagnetic Resonance ImagingMaleMice, TransgenicMolecular ImagingPositron Emission Tomography Computed TomographyPresenilin-1

MeSH Terms

Positron Emission Tomography Computed TomographyAlzheimer DiseaseAnimalsBrainHumansMacaca mulattaMagnetic Resonance ImagingMaleMice, TransgenicPresenilin-1Amyloid Precursor Protein SecretasesMolecular Imaging

Keywords

Amyloid precursor protein secretaseGamma secretaseNeuroscienceAmyloid precursor proteinPresenilinGenetically modified mouseAmyloid (mycology)Alzheimer's diseaseBiologyChemistryTransgeneDiseaseCell biologyMedicineBiochemistryGenePathologyMaleBrief Definitive ReportBrainMice, TransgenicMacaca mulattaMagnetic Resonance ImagingMolecular ImagingAlzheimer DiseasePositron Emission Tomography Computed TomographyPresenilin-1AnimalsHumansAmyloid Precursor Protein Secretases

Sustainable Development Goals

SDG 3: 3. Good health