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Comparison of the efficacy of MOE and PMO modifications of systemic antisense oligonucleotides in a severe SMA mouse model

Nucleic Acids Research(2020)10.1093/nar/gkaa126Source: DataRank Database

Comparison of the efficacy of MOE and PMO modifications of systemic antisense oligonucleotides in a severe SMA mouse model is a research paper published in Nucleic Acids Research (2020). On theSindex it has a DataRank of 0. It has been cited 83 times.

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Open Access83 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (8 grants)OA: goldTopics (42)IDs (PubMed, PMC)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (5)

Frank Rigo ORCID,C. Frank Bennett ORCID,Adrian R. Krainer,Yimin Hua ORCID,Lei Sheng ORCID

Live enrichment

PubMed:32103257 PMC:PMC7102994

National Natural Science Foundation of China

Grant: 81271423

National Natural Science Foundation of China

Grant: 81471298

National Natural Science Foundation of China

Grant: 81530035

National Institutes of Health

Grant: GM42699

NIGMS NIH HHS

Grant: R01 GM042699

NCI NIH HHS

Grant: P30 CA045508

NIGMS NIH HHS

Grant: R37 GM042699

National Institutes of Health

Grant: 1R01GM042699-01

BIOCHEMISTRY OF PRE-MRNA SPLICING

goldLicense: cc-by

publisherhttps://doi.org/10.1093/nar/gkaa126

publisherhttp://academic.oup.com/nar/article-pdf/48/6/2853/32977916/gkaa126.pdf

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7102994

Europe_PMChttps://europepmc.org/articles/PMC7102994

Europe_PMChttps://europepmc.org/articles/PMC7102994?pdf=render

Fields of Study

0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

MusclesSpinal CordMotor NeuronsNeuromuscular JunctionAnimalsMice, TransgenicHumansMuscular Atrophy, SpinalDisease Models, AnimalPhosphoric AcidsAmidesOligonucleotides, AntisenseTreatment OutcomeMotor ActivityRNA SplicingPhenotypeExonsSurvival of Motor Neuron 2 ProteinMorpholinos

Keywords

Motor NeuronsMusclesRNA SplicingNeuromuscular JunctionMice, TransgenicExonsMotor ActivityOligonucleotides, AntisenseAmidesMorpholinosMuscular Atrophy, SpinalSurvival of Motor Neuron 2 ProteinDisease Models, AnimalPhenotypeTreatment OutcomeChemical Biology and Nucleic Acid ChemistrySpinal CordAnimalsHumansPhosphoric Acids

Sustainable Development Goals

SDG 3: 3. Good health