Frank Rigo

Biochemistry, Genetics and Molecular BiologyMedicineNeuroscience

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 44 papers. Top paper: “Systematic screening identifies therapeutic antisense oligonucleotides for Hutchinson–Gilford progeria syndrome”.

Systematic screening identifies therapeutic antisense oligonucleotides for Hutchinson–Gilford progeria syndrome

Nature Medicine(2021)10.1038/s41591-021-01262-4

N/A

0.654DataRank · unranked

77 citations

Michaela Jackson, Stéphanie Klein, Asaf Shilo, C. Frank Bennett, Leslie B. Gordon +3 more

Suppression of proteolipid protein rescues Pelizaeus–Merzbacher disease

Nature(2020)10.1038/s41586-020-2494-3

N/A

0.654DataRank · unranked

77 citations

Lilianne Barbar, H. Elizabeth Shick, Berit Powers, Yuka Maeno-Hikichi, Mayur Madhavan +16 more

Astrocytic 4R tau expression drives astrocyte reactivity and dysfunction

JCI Insight(2021)10.1172/jci.insight.152012

N/A

0.571DataRank · unranked

44 citations

Kathleen M. Schoch, Chihiro Sato, Mariana Beltcheva, Kanta Horie, Frank Rigo +5 more

Antisense oligonucleotide jacifusen for FUS-ALS: an investigator-initiated, multicentre, open-label case series

The Lancet(2025)10.1016/s0140-6736(25)00513-6

N/A

0.538DataRank · unranked

35 citations

Matthew B. Harms, Vladislav A. Korobeynikov, Olivia M. Rifai, Benjamin N. Hoover, Elizabeth A. Harrington +30 more

Systemic therapy in an RNA toxicity mouse model with an antisense oligonucleotide therapy targeting a non-CUG sequence within the DMPK 3′UTR RNA

Human Molecular Genetics(2020)10.1093/hmg/ddaa060

N/A

0.529DataRank · unranked

33 citations

Qing Yu, Mahua Mandal, Frank Rigo, C. Frank Bennett, Mani S. Mahadevan +1 more

Tau seeds are subject to aberrant modifications resulting in distinct signatures

Cell Reports(2021)10.1016/j.celrep.2021.109037

N/A

0.505DataRank · unranked

28 citations

Aditi Ajit, Zarin Tabassum, Niyati Patel, Xu Tian, Youjun Chen +7 more

Modeling muscle regeneration in RNA toxicity mice

Human Molecular Genetics(2021)10.1093/hmg/ddab108

N/A

0.494DataRank · unranked

13 citations

Mahua Mandal, Jack M Giese, Frank Rigo, C. Frank Bennett, Mani S. Mahadevan +1 more

Reduction of nemo-like kinase increases lysosome biogenesis and ameliorates TDP-43–related neurodegeneration

Journal of Clinical Investigation(2023)10.1172/jci138207

N/A

0.425DataRank · unranked

16 citations

Youngseob Jung, Hiroshi Kokubu, Sowmithra Sowmithra, Luhan Ni, Chang‐Woo Lee +15 more

Modeling antisense oligonucleotide therapy in MECP2 duplication syndrome human iPSC-derived neurons reveals gene expression programs responsive to MeCP2 levels

Human Molecular Genetics(2024)10.1093/hmg/ddae135

N/A

0.383DataRank · unranked

10 citations

Yehezkel Sztainberg, Alexander J. Trostle, Harini P Tirumala, Ying‐Wooi Wan, Caroline L Harrop +10 more

Antisense oligonucleotides targeting UBE3A-ATS restore expression of UBE3A by relieving transcriptional interference

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.07.09.451826

N/A

0.292DataRank · unranked

6 citations

Dea Gorka, Ryan Drennan, Paymaan Jafar‐Nejad, Amanda J. Whipple, Leighton J. Core +4 more

Antisense oligonucleotides targeting the miR-29b binding site in the GRN mRNA increase progranulin translation

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.01.12.476053

N/A

0.241DataRank · unranked

4 citations

Subhashis Banerjee, Spencer A. Jones, Yousri Benchaar, Jasmine Bélanger, Myriam Sévigny +15 more

Corticosteroid sensitization drives opioid addiction

Molecular Psychiatry(2022)10.1038/s41380-022-01501-1

N/A

0DataRank · unranked

29 citations

Janaina C. M. Vendruscolo, M. Adrienne McGinn, Jorge Miranda‐Barrientos, Vez Repunte‐Canonigo, Gabriel D. Bossé +16 more

Premature transcription termination at the expanded GAA repeats and aberrant alternative polyadenylation contributes to theFrataxintranscriptional deficit in Friedreich’s ataxia

Human Molecular Genetics(2022)10.1093/hmg/ddac134

N/A

0DataRank · unranked

21 citations

Jixue Li, Jun Wang, Siyuan Zhang, Keith E. Giles, Thazha P. Prakash +4 more

Genetic interaction between Scn8a and potassium channel genes Kcna1 and Kcnq2

Epilepsia(2022)10.1111/epi.17374

N/A

0DataRank · unranked

19 citations

Julie Ziobro, Paymaan Jafar‐Nejad, Frank Rigo, Miriam H. Meisler, Sophie F. Hill

Difficulties translating antisense-mediated activation of Frataxin expression from cell culture to mice

RNA Biology(2022)10.1080/15476286.2022.2043650

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0DataRank · unranked

7 citations

Jun Wang, Xiulong Shen, Frank Rigo, Thahza P. Prakash, Марек Напиерала +2 more

HDAC6 Interacts With Poly (GA) and Modulates its Accumulation in c9FTD/ALS

Frontiers in Cell and Developmental Biology(2022)10.3389/fcell.2021.809942

N/A

0DataRank · unranked

6 citations

Yari Carlomagno, Tiffany W. Todd, Caroline Y. Jones, Mercedes Prudencio, Lillian M. Daughrity +16 more

Stathmin-2 loss leads to neurofilament-dependent axonal collapse driving motor and sensory denervation

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.12.11.519794

N/A

0DataRank · unranked

9 citations

Mariana Bravo‐Hernández, Maximiliano Presa, Michael W. Baughn, Ze’ev Melamed, Melinda S. Beccari +19 more

The RNA binding proteins hnRNP H and F regulate splicing of a MYC dependent HRAS exon in Prostate Cancer Cells

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.11.29.518269

N/A

0DataRank · unranked

1 citations

Harry Yang, Beatrice Zhang, John W. Phillips, Donghui Cheng, Frank Rigo +4 more

Mechanism of STMN2 cryptic splice-polyadenylation and its correction for TDP-43 proteinopathies

Science(2023)10.1126/science.abq5622

N/A

0DataRank · unranked

253 citations

Ze’ev Melamed, Jone López‐Erauskin, Melinda S. Beccari, Karen Ling, Aamir Zuberi +19 more

Stathmin-2 loss leads to neurofilament-dependent axonal collapse driving motor and sensory denervation

Nature Neuroscience(2023)10.1038/s41593-023-01496-0

N/A

0DataRank · unranked

49 citations

Mariana Bravo‐Hernández, Maximiliano Presa, Michael W. Baughn, Ze’ev Melamed, Melinda S. Beccari +21 more

G2C4 targeting antisense oligonucleotides potently mitigate TDP-43 dysfunction in human C9orf72 ALS/FTD induced pluripotent stem cell derived neurons

Acta Neuropathologica(2023)10.1007/s00401-023-02652-3

N/A

0DataRank · unranked

38 citations

Victoria Baskerville, Sampath Rapuri, Emma Mehlhop, Paymaan Jafar‐Nejad, Frank Rigo +5 more

The RNA-binding proteins hnRNP H and F regulate splicing of a MYC-dependent HRAS exon in prostate cancer cells

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2220190120

N/A

0DataRank · unranked

33 citations

Harry Yang, Beatrice Zhang, John W. Phillips, Donghui Cheng, Frank Rigo +4 more

Differential effects of SARM1 inhibition in traumatic glaucoma and EAE optic neuropathies

Molecular Therapy — Nucleic Acids(2023)10.1016/j.omtn.2023.02.029

N/A

0DataRank · unranked

32 citations

Wei Chen, Haowen Jiang, Haoliang Huang, Liping Liu, Fang Fang +11 more

Antisense oligonucleotides targeting the miR-29b binding site in the GRN mRNA increase progranulin translation

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.105475

N/A

0DataRank · unranked

13 citations

Subhashis Banerjee, Spencer A. Jones, Yousri Benchaar, Jasmine Bélanger, Myriam Sévigny +15 more

ASO silencing of a glycosyltransferase, Poglut1, improves the liver phenotypes in mouse models of Alagille syndrome

Hepatology(2023)10.1097/hep.0000000000000380

N/A

0DataRank · unranked

9 citations

Duncan Fox, Jennifer L. Burwinkel, Neda Zarrin‐Khameh, Soomin Cho, Armand Soriano +8 more

Modulation of Gene Expression in the Eye with Antisense Oligonucleotides

Nucleic Acid Therapeutics(2023)10.1089/nat.2023.0044

N/A

0DataRank · unranked

9 citations

Xin Gong, Fan Yan, Selina Aguilar, Frank Rigo, Thahza P. Prakash +3 more

Targeting nonsense-mediated RNA decay does not increase progranulin levels in the Grn R493X mouse model of frontotemporal dementia

PLoS ONE(2023)10.1371/journal.pone.0282822

N/A

0DataRank · unranked

5 citations

Michael L. Niehoff, Karen Ling, Paymaan Jafar‐Nejad, Frank Rigo, Susan A. Farr +3 more

G 2 C 4 targeting antisense oligonucleotides potently mitigate TDP-43 dysfunction in C9orf72 ALS/FTD human neurons

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.26.546581

N/A

0DataRank · unranked

0 citations

Victoria Baskerville, Sampath Rapuri, Emma Mehlhop, Paymaan Jafar‐Nejad, Frank Rigo +5 more

Employing splice-switching oligonucleotides and AAVrh74.U7 snRNA to target insulin receptor splicing and cancer hallmarks in osteosarcoma

Molecular Therapy Oncology(2024)10.1016/j.omton.2024.200908

N/A

0DataRank · unranked

7 citations

Akila S. Venkataramany, Matías Montes, John F. Kipp, Ryan D. Roberts, Nicolas Wein +5 more

Elevating microRNA levels by targeting biogenesis with steric-blocking antisense oligonucleotides

RNA(2024)10.1261/rna.080021.124

N/A

0DataRank · unranked

2 citations

Anthony J. Hinrich, Frank Rigo, Michelle L. Hastings, Mallory A. Havens

Antisense oligonucleotide therapy for patients with Friedreich’s ataxia carrying the c.165+5G>C splicing mutation

Molecular Therapy — Nucleic Acids(2025)10.1016/j.omtn.2025.102617

N/A

0DataRank · unranked

5 citations

Selina Aguilar, Thazha P. Prakash, Frank Rigo, David R. Lynch, Jill S. Napierala +2 more

Therapeutic antisense oligonucleotide mitigates retinal dysfunction in a pig model of CLN3 Batten disease

Nucleic Acids Research(2025)10.1093/nar/gkaf1141

N/A

0DataRank · unranked

2 citations

Jessica L. Centa, Vicki J. Swier, Wanda Pfeifer, Clarissa D. Booth, Karlee Albert +11 more

G4C2 Repeat RNA Initiates a POM121-Mediated Reduction in Specific Nucleoporins in C9orf72 ALS/FTD

Neuron(2020)10.1016/j.neuron.2020.06.027

N/A

0DataRank · unranked

169 citations

Benjamin L. Zaepfel, Lindsey R. Hayes, Boris Fitchman, Yuval Salzberg, En‐Ching Luo +10 more

Therapeutic antisense oligonucleotide mitigates retinal dysfunction in a pig model of CLN3 Batten disease

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.30.656864

N/A

0DataRank · unranked

0 citations

Jessica L. Centa, Vicki J. Swier, Wanda Pfeifer, Clarissa D. Booth, Karlee Albert +11 more

Scn8a Antisense Oligonucleotide Is Protective in Mouse Models of SCN8A Encephalopathy and Dravet Syndrome

Annals of Neurology(2020)10.1002/ana.25676

N/A

0DataRank · unranked

141 citations

Paymaan Jafar‐Nejad, Sophie F. Hill, Lucas D. Huffman, Corrine Smolen, Jacy L. Wagnon +9 more

Comparison of the efficacy of MOE and PMO modifications of systemic antisense oligonucleotides in a severe SMA mouse model

Nucleic Acids Research(2020)10.1093/nar/gkaa126

N/A

0DataRank · unranked

83 citations

Frank Rigo, C. Frank Bennett, Adrian R. Krainer, Yimin Hua, Lei Sheng

Direct Delivery of Antisense Oligonucleotides to the Middle and Inner Ear Improves Hearing and Balance in Usher Mice

Molecular Therapy(2020)10.1016/j.ymthe.2020.08.002

N/A

0DataRank · unranked

56 citations

Bifeng Pan, Abhilash Ponnath, Christopher M. Tran, Carl Nist-Lund, Alice Galvin +12 more

Therapeutic efficacy of antisense oligonucleotides in mouse models of CLN3 Batten disease

Nature Medicine(2020)10.1038/s41591-020-0986-1

N/A

0DataRank · unranked

53 citations

Francine M. Jodelka, Anthony J. Hinrich, Tyler B. Johnson, Joseph Ochaba, Michaela Jackson +5 more

Progress towards drug discovery for Friedreich’s Ataxia: Identifying synthetic oligonucleotides that more potently activate expression of human frataxin protein

Bioorganic & Medicinal Chemistry(2020)10.1016/j.bmc.2020.115472

N/A

0DataRank · unranked

17 citations

Johnathan Wong, Thahza P. Prakash, Frank Rigo, Yanjie Li, Марек Напиерала +2 more

ALS-associated genes in SCA2 mouse spinal cord transcriptomes

Human Molecular Genetics(2020)10.1093/hmg/ddaa072

N/A

0DataRank · unranked

31 citations

Warunee Dansithong, Lance Pflieger, Sharan Paul, Mandi Gandelman, Karla P. Figueroa +4 more

G 4 C 2 repeat RNA mediates the disassembly of the nuclear pore complex in C9orf72 ALS/FTD

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.02.13.947721

N/A

0DataRank · unranked

3 citations

Benjamin L. Zaepfel, Lindsey R. Hayes, Boris Fitchman, Yuval Salzberg, Kelly Bowen +7 more

Reduction of Nemo-like kinase increases lysosome biogenesis and ameliorates TDP-43-related neurodegeneration

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.19.049395

N/A

0DataRank · unranked

1 citations

Hiroshi Kokubu, Paul J. Lee, Yangfei Xiang, Kimberly P. Luttik, Armand Soriano +10 more

Nuclear accumulation of CHMP7 initiates nuclear pore complex injury and subsequent TDP-43 dysfunction in sporadic and familial ALS

Science Translational Medicine(2021)10.1126/scitranslmed.abe1923

N/A

0DataRank · unranked

148 citations

Victoria Baskerville, Benjamin L. Zaepfel, Dennis W. Dickson, Frank Rigo, Frank Bennett +3 more

Antisense oligonucleotide therapy in a humanized mouse model of MECP2 duplication syndrome

Science Translational Medicine(2021)10.1126/scitranslmed.aaz7785

N/A

0DataRank · unranked

60 citations

Yehezkel Sztainberg, Qi Wang, Sameer S. Bajikar, Alexander J. Trostle, Ying‐Wooi Wan +6 more