FAVOR 2.0: A reengineered functional annotation of variants online resource for interpreting genomic variation is a dataset published in Nucleic Acids Research (2025). On theSindex it has a DataRank of 0.115, placing it in the top 71.8% of the data-sharing corpus. It has been cited 1 time, with 1 citing works in its 1-hop citation network. Its calibrated FAIR score is 52/100.
Ranks in the top 72% for downstream scientific impact
DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?
FAIR checklist signals are shown for context only and do not affect DataRank scoring.
Full FAIR picture · advisory
The headline score is computed from the scored criteria — the fact-shaped checks (a repository, an accession, a licence) that two independent models agree on. The advisory criteria below are real FAIR guidance but rest on judgment calls that models read differently, so they inform without moving the number.
“The FAVOR database can also be accessed at https://dataverse.harvard.edu/dataverse/favor”
The paper gives a web address for the data, not a persistent identifier scheme such as a DOI or accession.
RDA-F1-01D — FAIR Data Maturity Model: 'Data is identified by a persistent identifier' (priorit · RDA-F1-02D — FAIR Data Maturity Model: 'Data is identified by a globally unique identifier' · FsF-F1-02D — F-UJI/FAIRsFAIR: 'Data is assigned a persistent identifier'
“The FAVOR database can also be accessed at https://dataverse.harvard.edu/dataverse/favor”
Harvard Dataverse is a named data repository listed in re3data and FAIRsharing.
RDA-F4-01M — FAIR Data Maturity Model: metadata is offered so it can be harvested and indexed ( · NIH DMS Policy Element 4 (NOT-OD-21-014) — name the repository where data will be archived · NSTC Desirable Characteristics of Data Repositories (2022) — 'Long-Term Sustainability', 'Reten
“The FAVOR database can also be accessed at https://dataverse.harvard.edu/dataverse/favor”
The dataset's identifier (URL) appears only in body text, not as a reference-list entry.
FORCE11 Joint Declaration of Data Citation Principles (2014) — data should be cited as a first- · RDA-F3-01M — metadata clearly and explicitly includes the identifier of the data it describes · FsF-F3-01M — F-UJI: 'Metadata includes the identifier of the data it describes'
Advisory · not in the published score
“The FAVOR portal is freely available at https://favor.genohub.org/ with detailed documentation. The FAVOR database can also be accessed at https://dataverse.harvard.edu/dataverse/favor . FAVOR-API can be found at https://docs.genohub.org/”
The data-availability statement points to a repository record (Harvard Dataverse) with a link, which is Colavizza category 3. [majority verdict 'yes' (4/5 passes agreed)]
Colavizza, Hrynaszkiewicz, Staden, Whitaker & McGillivray (2020), 'The citation advantage of li · Springer Nature research data policy — Data Availability Statements: standard statement templat · RDA-F3-01M — metadata clearly and explicitly includes the identifier of the data it describes
“The new FAVOR database includes (i) comprehensive gene and protein annotations; (ii) a significantly expanded collection of global variant functional annotations; (iii) tissue- and cell-type–specific variant functional annotations; and (iv) support for both hg38 and hg19 reference genomes.”
The dataset content is described in running prose, not in an itemised inventory such as a table or section.
RDA-F2-01M — 'Rich metadata is provided to allow discovery' (priority Essential) · FsF-F2-01M — F-UJI: 'Metadata includes descriptive core elements to support data findability' · FsF-R1-01MD — F-UJI: 'Metadata specifies the content of the data'
“The FAVOR portal is freely available at https://favor.genohub.org/ with detailed documentation.”
The text provides a route to the data with no stated precondition; it is described as 'freely available'.
RDA-A1.1-01D — 'Data is accessible through a free access protocol' · FsF-A1-01M — F-UJI: 'Metadata contains access level and access conditions of the data' · NSTC Desirable Characteristics of Data Repositories (2022) — 'Free and Easy Access'
Advisory · not in the published score
“As a fully open-access resource, FAVOR database files are available in a compressed form on the Harvard Dataverse for efficient and effortless downloads.”
The paper explicitly labels the data as 'fully open-access', which is a standard access-level label.
FsF-A1-01M — F-UJI: 'Metadata contains access level and access conditions of the data' · RDA-A1-01M — metadata contains information to enable the user to get access to the data · COAR Controlled Vocabularies — Access Rights v1.0 (open / embargoed / restricted / metadata-onl
“The FAVOR portal is freely available at https://favor.genohub.org/ with detailed documentation.”
The data are not sensitive human-subject data; the paper states they are freely available with no gatekeeper, so no gatekeeper is named.
NIH Genomic Data Sharing Policy (NOT-OD-14-124) — controlled-access via a Data Access Committee · RDA-A1.2-01D — 'Data is accessible through an access protocol that supports authentication and · NIH DMS Policy Element 5 (NOT-OD-21-014) — Access, Distribution, or Reuse Considerations (conse
No sentence states when the data become available or how long they persist. [majority verdict 'no' (2/5 passes agreed)]
NIH DMS Plan Element 4 (NOT-OD-21-014) — Data Preservation, Access, and Associated Timelines · NSTC Desirable Characteristics (2022), Organizational Infrastructure: 'Retention Policy' · RDA-A2-01M — 'Metadata is guaranteed to remain available after data is no longer available'
“database files are available in a compressed form on the Harvard Dataverse for efficient and effortless downloads.”
No file format token is named for the released data; the form is described only as 'compressed'.
FsF-R1.3-02D — F-UJI: 'Data is available in a file format recommended by the target research co · RDA-R1.3-02D — data is expressed in a machine-understandable community standard · RDA-I1-01D — data uses a knowledge representation expressed in a standardised format
Advisory · not in the published score
“Major annotation sources such as gnomAD, ClinVar, and GTEx will be updated at least annually or as new versions are released.”
The paper names data sources but not a community standard checklist, schema, or ontology applied to the data.
RDA-R1.3-01M — 'Metadata complies with a community standard' (priority Essential) · RDA-R1.3-01D — 'Data complies with a community standard' · RDA-I2-01M — '(Meta)data use vocabularies that follow FAIR principles'
“Major annotation sources such as gnomAD, ClinVar, and GTEx will be updated at least annually or as new versions are released.”
The paper names external resources but does not provide their identifiers (accessions or DOIs). [majority verdict 'no' (4/5 passes agreed)]
RDA-I3-01M — '(meta)data include references to other (meta)data' · RDA-I3-03M — 'metadata includes qualified references to other metadata' · FsF-I3-01M — F-UJI: 'Metadata includes links between the data and its related entities'
“As a fully open-access resource, FAVOR database files are available in a compressed form on the Harvard Dataverse for efficient and effortless downloads.”
The paper labels the resource as 'open-access' but does not name a standard licence (e.g., CC0, CC BY) for the data.
RDA-R1.1-01M — 'Metadata includes information about the licence under which the data can be reu · RDA-R1.1-02M — 'Metadata refers to a standard reuse licence' · RDA-R1.1-03M — 'Metadata refers to a machine-understandable reuse licence'
“The new release of the FAVOR database provides far more comprehensive functional annotations of variants, genes, and proteins across the genome.”— not found in the paper; verdict downgraded
The paper identifies the snapshot as 'the new release' and 'FAVOR 2.0', which is a version token. [downgraded to 'partial' — no verifiable quote from the paper] [majority verdict 'partial' (3/5 passes agreed)]
DataCite Metadata Schema 4.6 — the 'Version' property · RDA-R1.2-01M — provenance information (which version was used is provenance) · NSTC Desirable Characteristics of Data Repositories (2022) — 'Provenance', 'Retention Policy'
“FAVOR-API can be found at https://docs.genohub.org/”
The paper gives a URL for API documentation but not a code repository or archive DOI for the software.
NIH DMS Policy Element 2 (NOT-OD-21-014) — 'Related Tools, Software and/or Code' · FAIR4RS Principles v1.0 (Chue Hong et al., 2022; RDA/FORCE11/ReSA) — FAIR Principles for Resear · FORCE11 Software Citation Principles (Smith, Katz & Niemeyer, 2016, PeerJ CS 2:e86)
“This work was supported by National Institute of Health (NIH) grant nos R35–CA197449, P01–CA134294, U19–CA203654, and R01–HL113338 (to X. Lin), U01–HG012064 (to Z. Weng and X. Lin), U01–HG009088 (to X. Lin, S.R.S., and B.M.N.).”
The paper provides specific grant numbers from a named funder (NIH).
DataCite Metadata Schema 4.6 — 'FundingReference' property (funderName, funderIdentifier, award · Crossref Funder Registry — canonical funder identifiers for funding metadata · RDA-F2-01M — rich metadata provided to allow discovery (funding is part of the descriptive reco
Advisory · not in the published score
No specific instruments, tools, or software used to produce the data are named. [majority verdict 'no' (2/5 passes agreed)]
RDA-R1.2-01M — 'Metadata includes provenance information according to community- specific standa · FsF-R1.2-01M — F-UJI: 'Metadata includes provenance information about data creation or generati · W3C PROV-O (W3C Recommendation, 2013) — the entity/activity/agent model of provenance
“The FAVOR portal is freely available at https://favor.genohub.org/ with detailed documentation.”
The paper mentions 'detailed documentation' but does not specify that a codebook or data dictionary accompanies the deposited data. [majority verdict 'no' (4/5 passes agreed)]
RDA-R1-01M — '(Meta)data are richly described with a plurality of accurate and relevant attribu · FsF-R1-01MD — F-UJI: 'Metadata specifies the content of the data' · NIH DMS Policy Element 3 (NOT-OD-21-014) — Standards (documentation and metadata to accompany t
Calibrated FAIR score — a parallel quality metric, independent of the DataRank citation score. See the full evaluation →
Base Score Contribution
0.104
From this paper's citation signal
Citation Network Contribution
0.0107
From 1 citing papers with measurable signal
Ranked by each citer's contribution to N(p) — log1p(Cq) divided by its reference count — out of 1 citer.
NIH
Grant: R35–CA197449
NIH
Grant: P01–CA134294
NIH
Grant: U19–CA203654
NIH
Grant: R01–HL113338
NIH
Grant: U01–HG012064
NIH
Grant: U01–HG009088
NHLBI NIH HHS
Grant: R01 HL113338
NHGRI NIH HHS
Grant: U01 HG012064
NCI NIH HHS
Grant: U19 CA203654
NIH HHS
Grant: P01-CA134294
NIEHS NIH HHS
Grant: P42 ES030990
NIH HHS
Grant: R35-CA197449
NHGRI NIH HHS
Grant: U01 HG009088
NIH HHS
Grant: U01-HG009088
NCI NIH HHS
Grant: P01 CA134294
NIH HHS
Grant: U19-CA203654
NIH HHS
Grant: R01-HL113338
NCI NIH HHS
Grant: R35 CA197449
NIH HHS
Grant: U01-HG012064
MeSH Terms